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The detection of nuclei and cells in histology images is of great value in both clinical practice and pathological studies. However, multiple reasons such as morphological variations of nuclei or cells make it a challenging task where…

计算机视觉与模式识别 · 计算机科学 2021-06-28 Yibao Sun , Xingru Huang , Huiyu Zhou , Qianni Zhang

In healthcare, it is essential to explain the decision-making process of machine learning models to establish the trustworthiness of clinicians. This paper introduces BI-RADS-Net, a novel explainable deep learning approach for cancer…

计算机视觉与模式识别 · 计算机科学 2021-10-11 Boyu Zhang , Aleksandar Vakanski , Min Xian

The segmentation of diseases is a popular topic explored by researchers in the field of machine learning. Brain tumors are extremely dangerous and require the utmost precision to segment for a successful surgery. Patients with tumors…

图像与视频处理 · 电气工程与系统科学 2022-04-05 Sanskriti Singh

Nuclei segmentation is a fundamental task in digital pathology analysis and can be automated by deep learning-based methods. However, the development of such an automated method requires a large amount of data with precisely annotated masks…

计算机视觉与模式识别 · 计算机科学 2021-11-25 Jiangbo Shi , Chang Jia , Zeyu Gao , Tieliang Gong , Chunbao Wang , Chen Li

Recent advances in machine learning are transforming medical image analysis, particularly in cancer detection and classification. Techniques such as deep learning, especially convolutional neural networks (CNNs) and vision transformers…

图像与视频处理 · 电气工程与系统科学 2024-11-05 Arezoo Borji , Gernot Kronreif , Bernhard Angermayr , Sepideh Hatamikia

Accurately and quickly binuclear cell (BC) detection plays a significant role in predicting the risk of leukemia and other malignant tumors. However, manual microscopy counting is time-consuming and lacks objectivity. Moreover, with the…

计算机视觉与模式识别 · 计算机科学 2022-08-29 Baomin Wang , Geng Hu , Dan Chen , Lihua Hu , Cheng Li , Yu An , Guiping Hu , Guang Jia

Digital pathology is one of the most significant developments in modern medicine. Pathological examinations are the gold standard of medical protocols and play a fundamental role in diagnosis. Recently, with the advent of digital scanners,…

图像与视频处理 · 电气工程与系统科学 2021-12-09 Mahdi Arab Loodaricheh , Nader Karimi , Shadrokh Samavi

Background and Aim: Recently, deep learning using convolutional neural network has been used successfully to classify the images of breast cells accurately. However, the accuracy of manual classification of those histopathological images is…

图像与视频处理 · 电气工程与系统科学 2021-08-11 Ashu Thapa , Abeer Alsadoon , P. W. C. Prasad , Simi Bajaj , Omar Hisham Alsadoon , Tarik A. Rashid , Rasha S. Ali , Oday D. Jerew

In this study, we present an interpretable deep learning framework for the early detection of breast cancer using quantitative features extracted from digitized fine needle aspirate (FNA) images of breast masses. Our deep neural network,…

计算机视觉与模式识别 · 计算机科学 2025-10-28 Bishal Chhetri , B. V. Rathish Kumar

Identification and counting of cells and mitotic figures is a standard task in diagnostic histopathology. Due to the large overall cell count on histological slides and the potential sparse prevalence of some relevant cell types or mitotic…

计算机视觉与模式识别 · 计算机科学 2017-09-08 Marc Aubreville , Maximilian Krappmann , Christof Bertram , Robert Klopfleisch , Andreas Maier

Computer-aided diagnosis (CAD) based on histopathological imaging has progressed rapidly in recent years with the rise of machine learning based methodologies. Traditional approaches consist of training a classification model using features…

计算机视觉与模式识别 · 计算机科学 2019-03-29 Junaid Malik , Serkan Kiranyaz , Suchitra Kunhoth , Turker Ince , Somaya Al-Maadeed , Ridha Hamila , Moncef Gabbouj

Microscopic histology image analysis is a cornerstone in early detection of breast cancer. However these images are very large and manual analysis is error prone and very time consuming. Thus automating this process is in high demand. We…

计算机视觉与模式识别 · 计算机科学 2018-10-23 Ismaël Koné , Lahsen Boulmane

With the increase in the use of deep learning for computer-aided diagnosis in medical images, the criticism of the black-box nature of the deep learning models is also on the rise. The medical community needs interpretable models for both…

图像与视频处理 · 电气工程与系统科学 2020-12-21 Mookund Sureka , Abhijeet Patil , Deepak Anand , Amit Sethi

Accurate and scalable cancer diagnosis remains a critical challenge in modern pathology, particularly for malignancies such as breast, prostate, bone, and cervical, which exhibit complex histological variability. In this study, we propose a…

图像与视频处理 · 电气工程与系统科学 2025-08-18 Faisal Ahmed

Breast cancer is one of the most common and dangerous cancers in women, while it can also afflict men. Breast cancer treatment and detection are greatly aided by the use of histopathological images since they contain sufficient phenotypic…

图像与视频处理 · 电气工程与系统科学 2023-04-12 Md Ishtyaq Mahmud , Muntasir Mamun , Ahmed Abdelgawad

Accurate subtyping of renal cell carcinoma (RCC) is of crucial importance for understanding disease progression and for making informed treatment decisions. New discoveries of significant alterations to mitochondria between subtypes make…

机器学习 · 计算机科学 2016-08-03 Peter J. Schüffler , Judy Sarungbam , Hassan Muhammad , Ed Reznik , Satish K. Tickoo , Thomas J. Fuchs

Automated detection of cervical cancer cells or cell clumps has the potential to significantly reduce error rate and increase productivity in cervical cancer screening. However, most traditional methods rely on the success of accurate cell…

计算机视觉与模式识别 · 计算机科学 2019-12-24 Yixiong Liang , Zhihong Tang , Meng Yan , Jialin Chen , Qing Liu , Yao Xiang

Hematoxylin and Eosin (H&E)-stained images are commonly used to detect nuclear or cancerous regions in cells from images captured by a microscope. Identifying cancer cytoplasm is crucial for determining the type of cancer; hence, obtaining…

图像与视频处理 · 电气工程与系统科学 2025-07-08 Rebeka Sultana , Hibiki Horibe , Tomoaki Murakami , Ikuko Shimizu

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and…

计算机视觉与模式识别 · 计算机科学 2023-06-06 Yang Zhou , Yongjian Wu , Zihua Wang , Bingzheng Wei , Maode Lai , Jianzhong Shou , Yubo Fan , Yan Xu

Simultaneous segmentation and classification of nuclei in digital histology play an essential role in computer-assisted cancer diagnosis; however, it remains challenging. The highest achieved binary and multi-class Panoptic Quality (PQ)…

计算机视觉与模式识别 · 计算机科学 2024-04-29 Ibtihaj Ahmad , Syed Muhammad Israr , Zain Ul Islam