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Compared to traditional methods, Deep Learning (DL) becomes a key technology for computer vision tasks. Synthetic data generation is an interesting use case for DL, especially in the field of medical imaging such as Magnetic Resonance…
Immunohistochemistry (IHC) is essential for assessing specific immune biomarkers like Human Epidermal growth-factor Receptor 2 (HER2) in breast cancer. However, the traditional protocols of obtaining IHC stains are resource-intensive,…
Digital histology images are amenable to the application of convolutional neural network (CNN) for analysis due to the sheer size of pixel data present in them. CNNs are generally used for representation learning from small image patches…
Histological staining is the gold standard for tissue examination in clinical pathology and life-science research, which visualizes the tissue and cellular structures using chromatic dyes or fluorescence labels to aid the microscopic…
In the last few years, we have witnessed the rise of a series of deep learning methods to generate synthetic images that look extremely realistic. These techniques prove useful in the movie industry and for artistic purposes. However, they…
The proliferative activity of breast tumors, which is routinely estimated by counting of mitotic figures in hematoxylin and eosin stained histology sections, is considered to be one of the most important prognostic markers. However, mitosis…
Micro Abstract: A recent study from GLOBOCAN disclosed that during 2018 two million women worldwide had been diagnosed from breast cancer. This study presents a computer-aided diagnosis system based on convolutional neural networks as an…
Hematoxylin and eosin (H&E) staining visualizes histology but lacks specificity for diagnostic markers. Immunohistochemistry (IHC) staining provides protein-targeted staining but is restricted by tissue availability and antibody…
Deep learning has been shown to be useful to detect breast cancer metastases by analyzing whole slide images of sentinel lymph nodes. However, it requires extensive scanning and analysis of all the lymph nodes slides for each case. Our deep…
Many medical and biological protocols for analyzing individual biological cells involve morphological evaluation based on cell staining, designed to enhance imaging contrast and enable clinicians and biologists to differentiate between…
It is a critical task to evalaute HER2 expression level accurately for breast cancer evaluation and targeted treatment therapy selection. However, the standard multi-step Immunohistochemistry (IHC) staining is resource-intensive, expensive,…
Digitally retouching images has become a popular trend, with people posting altered images on social media and even magazines posting flawless facial images of celebrities. Further, with advancements in Generative Adversarial Networks…
Accurate and fast histological staining is crucial in histopathology, impacting diagnostic precision and reliability. Traditional staining methods are time-consuming and subjective, causing delays in diagnosis. Digital pathology plays a…
Breast cancer is a health problem that affects mainly the female population. An early detection increases the chances of effective treatment, improving the prognosis of the disease. In this regard, computational tools have been proposed to…
Segmentation of histopathology sections is an ubiquitous requirement in digital pathology and due to the large variability of biological tissue, machine learning techniques have shown superior performance over standard image processing…
In the realm of dermatological diagnoses, where the analysis of dermatoscopic and microscopic skin lesion images is pivotal for the accurate and early detection of various medical conditions, the costs associated with creating diverse and…
Breast cancer presents a significant healthcare challenge globally, demanding precise diagnostics and effective treatment strategies, where histopathological examination of Hematoxylin and Eosin (H&E) stained tissue sections plays a central…
Histology method is vital in the diagnosis and prognosis of cancers and many other diseases. For the analysis of histopathological images, we need to detect and segment all gland structures. These images are very challenging, and the task…
Data scarcity and class imbalance are two fundamental challenges in many machine learning applications to healthcare. Breast cancer classification in mammography exemplifies these challenges, with a malignancy rate of around 0.5% in a…
Precision medicine has become a central focus in breast cancer management, advancing beyond conventional methods to deliver more precise and individualized therapies. Traditionally, histopathology images have been used primarily for…