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We develop factor copula models for analysing the dependence among mixed continuous and discrete responses. Factor copula models are canonical vine copulas that involve both observed and latent variables, hence they allow tail, asymmetric…

统计方法学 · 统计学 2020-11-18 Sayed H. Kadhem , Aristidis K. Nikoloulopoulos

Even though convolutional neural networks (CNNs) are driving progress in medical image segmentation, standard models still have some drawbacks. First, the use of multi-scale approaches, i.e., encoder-decoder architectures, leads to a…

计算机视觉与模式识别 · 计算机科学 2020-02-18 Ashish Sinha , Jose Dolz

We describe a robust, fast, and memory-efficient procedure that can cluster millions of structures derived from molecular dynamics simulations. The essence of the method is based on a peak-picking algorithm applied to three- and…

生物大分子 · 定量生物学 2015-12-15 Athanasios S. Baltzis , Panagiotis I. Koukos , Nicholas M. Glykos

Multi-view data are increasingly prevalent in practice. It is often relevant to analyze the relationships between pairs of views by multi-view component analysis techniques such as Canonical Correlation Analysis (CCA). However, data may…

机器学习 · 统计学 2019-12-10 Eric Lei , Kyle Miller , Michael R. Pinsky , Artur Dubrawski

Composite development indicators used in policy making often subjectively aggregate a restricted set of indicators. We show, using dimensionality reduction techniques, including Principal Component Analysis (PCA) and for the first time…

综合经济学 · 经济学 2020-03-27 Anshul Verma , Orazio Angelini , Tiziana Di Matteo

Multi-agent imitation learning aims to train multiple agents to perform tasks from demonstrations by learning a mapping between observations and actions, which is essential for understanding physical, social, and team-play systems. However,…

机器学习 · 计算机科学 2021-07-13 Hongwei Wang , Lantao Yu , Zhangjie Cao , Stefano Ermon

Integration of heterogeneous and high-dimensional multi-omics data is becoming increasingly important in understanding genetic data. Each omics technique only provides a limited view of the underlying biological process and integrating…

机器学习 · 计算机科学 2023-04-13 Chen Zhao , Anqi Liu , Xiao Zhang , Xuewei Cao , Zhengming Ding , Qiuying Sha , Hui Shen , Hong-Wen Deng , Weihua Zhou

Capturing complex dependence structures between outcome variables (e.g., study endpoints) is of high relevance in contemporary biomedical data problems and medical research. Distributional copula regression provides a flexible tool to model…

统计方法学 · 统计学 2022-02-28 Nicolai Hans , Nadja Klein , Florian Faschingbauer , Michael Schneider , Andreas Mayr

Molecular structures of RNA molecules reconstructed from X-ray crystallography frequently contain errors. Motivated by this problem we examine clustering on a torus since RNA shapes can be described by dihedral angles. A previously…

生物大分子 · 定量生物学 2021-04-02 Henrik Wiechers , Benjamin Eltzner , Stephan F. Huckemann , Kanti V. Mardia

For the analysis of clustered survival data, two different types of models that take the association into account, are commonly used: frailty models and copula models. Frailty models assume that conditional on a frailty term for each…

统计方法学 · 统计学 2014-01-10 Leen Prenen , Roel Braekers , Luc Duchateau

Genetic data are frequently categorical and have complex dependence structures that are not always well understood. For this reason, clustering and classification based on genetic data, while highly relevant, are challenging statistical…

统计方法学 · 统计学 2016-06-13 Gabriela Bettella Cybis , Marcio Valk , Silvia Regina Costa Lopes

Multi-view clustering has become a significant area of research, with numerous methods proposed over the past decades to enhance clustering accuracy. However, in many real-world applications, it is crucial to demonstrate a clear…

机器学习 · 计算机科学 2025-02-07 Mudi Jiang , Lianyu Hu , Zengyou He , Zhikui Chen

An extension of the latent class model is presented for clustering categorical data by relaxing the classical "class conditional independence assumption" of variables. This model consists in grouping the variables into inter-independent and…

统计计算 · 统计学 2015-10-01 Matthieu Marbac , Christophe Biernacki , Vincent Vandewalle

This paper proposes multivariate copula models for hierarchical data. They account for two types of correlation: one is between variables measured on the same unit and the other is a correlation between units in the same cluster. This model…

统计方法学 · 统计学 2023-04-24 Talagbe Gabin Akpo , Louis-Paul Rivest

A precise assessment of the risk of breast lesions can greatly lower it and assist physicians in choosing the best course of action. To categorise breast lesions, the majority of current computer-aided systems only use characteristics from…

图像与视频处理 · 电气工程与系统科学 2025-08-25 Muhaisin Tiyumba Nantogmah , Abdul-Barik Alhassan , Salamudeen Alhassan

Microbiome data analysis is essential for understanding host health and disease, yet its inherent sparsity and noise pose major challenges for accurate imputation, hindering downstream tasks such as biomarker discovery. Existing imputation…

机器学习 · 计算机科学 2025-08-01 Rabeya Tus Sadia , Qiang Cheng

Diverse applications - particularly in tumour subtyping - have demonstrated the importance of integrative clustering techniques for combining information from multiple data sources. Cluster-Of-Clusters Analysis (COCA) is one such approach…

机器学习 · 统计学 2020-08-05 Alessandra Cabassi , Paul D. W. Kirk

Single-cell multi-view clustering enables the exploration of cellular heterogeneity within the same cell from different views. Despite the development of several multi-view clustering methods, two primary challenges persist. Firstly, most…

基因组学 · 定量生物学 2023-11-30 Dayu Hu , Zhibin Dong , Ke Liang , Jun Wang , Siwei Wang , Xinwang Liu

With the advance of technology, entities can be observed in multiple views. Multiple views containing different types of features can be used for clustering. Although multi-view clustering has been successfully applied in many applications,…

机器学习 · 计算机科学 2016-04-20 Weixiang Shao , Jiawei Zhang , Lifang He , Philip S. Yu

While several Gaussian mixture models-based biclustering approaches currently exist in the literature for continuous data, approaches to handle discrete data have not been well researched. A multivariate Poisson-lognormal (MPLN) model-based…

统计方法学 · 统计学 2025-03-13 Caitlin Kral , Evan Chance , Ryan Browne , Sanjeena Subedi