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We develop a flexible framework for modeling high-dimensional imaging data observed longitudinally. The approach decomposes the observed variability of repeatedly measured high-dimensional observations into three additive components: a…

Deformable templates, or atlases, are images that represent a prototypical anatomy for a population, and are often enhanced with probabilistic anatomical label maps. They are commonly used in medical image analysis for population studies…

计算机视觉与模式识别 · 计算机科学 2025-11-18 Marianne Rakic , Andrew Hoopes , S. Mazdak Abulnaga , Mert R. Sabuncu , John V. Guttag , Adrian V. Dalca

T2-weighted magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI) are essential components for cervical cancer diagnosis. However, combining these channels for training deep learning models are challenging due to…

图像与视频处理 · 电气工程与系统科学 2023-06-21 Reza Kalantar , Sebastian Curcean , Jessica M Winfield , Gigin Lin , Christina Messiou , Matthew D Blackledge , Dow-Mu Koh

Accurate spatial correspondence between medical images is essential for longitudinal analysis, lesion tracking, and image-guided interventions. Medical image registration methods rely on local intensity-based similarity measures, which fail…

计算机视觉与模式识别 · 计算机科学 2026-02-24 Xingyu Zhang , Anna Reithmeir , Fryderyk Kögl , Rickmer Braren , Julia A. Schnabel , Daniel M. Lang

Accurate and realistic simulation of high-dimensional medical images has become an important research area relevant to many AI-enabled healthcare applications. However, current state-of-the-art approaches lack the ability to produce…

图像与视频处理 · 电气工程与系统科学 2021-09-30 Daniele Ravi , Stefano B. Blumberg , Silvia Ingala , Frederik Barkhof , Daniel C. Alexander , Neil P. Oxtoby

Deep Implicit Functions (DIFs) represent 3D geometry with continuous signed distance functions learned through deep neural nets. Recently DIFs-based methods have been proposed to handle shape reconstruction and dense point correspondences…

计算机视觉与模式识别 · 计算机科学 2022-03-23 Shanlin Sun , Kun Han , Deying Kong , Hao Tang , Xiangyi Yan , Xiaohui Xie

Diffusion tensor imaging (DTI) provides crucial insights into the microstructure of the human brain, but it can be time-consuming to acquire compared to more readily available T1-weighted (T1w) magnetic resonance imaging (MRI). To address…

计算机视觉与模式识别 · 计算机科学 2025-04-22 Shaorong Zhang , Tamoghna Chattopadhyay , Sophia I. Thomopoulos , Jose-Luis Ambite , Paul M. Thompson , Greg Ver Steeg

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized by atypical functional brain connectivity and subtle structural alterations. rs-fMRI has been widely used to identify disruptions in large-scale brain…

计算机视觉与模式识别 · 计算机科学 2026-03-17 Ansar Rahman , Hassan Shojaee-Mend , Sepideh Hatamikia

Deep Implicit Functions (DIFs) have gained popularity in 3D computer vision due to their compactness and continuous representation capabilities. However, addressing dense correspondences and semantic relationships across DIF-encoded shapes…

计算机视觉与模式识别 · 计算机科学 2023-07-06 Kun Han , Shanlin Sun , Xiaohui Xie

Longitudinal fMRI datasets hold great promise for the study of neurodegenerative diseases, but realizing their potential depends on extracting accurate fMRI-based brain measures in individuals over time. This is especially true for rare,…

\hspace{2mm} Diffusion-weighted magnetic resonance imaging (dMRI) of the brain offers unique capabilities including noninvasive probing of tissue microstructure and structural connectivity. It is widely used for clinical assessment of…

图像与视频处理 · 电气工程与系统科学 2025-12-30 Davood Karimi , Simon K. Warfield

In this paper, we introduce a novel structural holistic Atlas (holiAtlas) of the human brain anatomy based on multimodal and high-resolution MRI that covers several anatomical levels from the organ to the substructure level, using a new…

Portable, ultra-low-field (ULF) magnetic resonance imaging has the potential to expand access to neuroimaging but currently suffers from coarse spatial and angular resolutions and low signal-to-noise ratios. Diffusion tensor imaging (DTI),…

Diffusion Magnetic Resonance Imaging (DMRI) is the only non-invasive imaging technique which is able to detect the principal directions of water diffusion as well as neurites density in the human brain. Exploiting the ability of Spherical…

计算机视觉与模式识别 · 计算机科学 2017-09-04 Mauro Zucchelli , Maxime Descoteaux , Gloria Menegaz

Anatomy shape modeling is a fundamental problem in medical data analysis. However, the geometric complexity and topological variability of anatomical structures pose significant challenges to accurate anatomical shape generation. In this…

计算机视觉与模式识别 · 计算机科学 2026-03-13 Guoqing Zhang , Jingyun Yang , Siqi Chen , Anping Zhang , Yang Li

Major depressive disorder (MDD) is a common neuropsychiatric condition whose accurate diagnosis from resting-state functional magnetic resonance imaging (rs-fMRI) remains difficult. Dynamic functional connectivity (DFC) captures…

计算机视觉与模式识别 · 计算机科学 2026-05-26 Muhammad Asif Hasan , Yanming Zhu , Xuefei Yin , Alan Wee-Chung Liew

Temporal volume images with 3D+t (4D) information are often used in medical imaging to statistically analyze temporal dynamics or capture disease progression. Although deep-learning-based generative models for natural images have been…

图像与视频处理 · 电气工程与系统科学 2022-06-28 Boah Kim , Jong Chul Ye

The structural network of the brain, or structural connectome, can be represented by fiber bundles generated by a variety of tractography methods. While such methods give qualitative insights into brain structure, there is controversy over…

计算机视觉与模式识别 · 计算机科学 2022-06-15 Kristen M. Campbell , Haocheng Dai , Zhe Su , Martin Bauer , P. Thomas Fletcher , Sarang C. Joshi

Joint registration of a stack of 2D histological sections to recover 3D structure (``3D histology reconstruction'') finds application in areas such as atlas building and validation of \emph{in vivo} imaging. Straightforward pairwise…

图像与视频处理 · 电气工程与系统科学 2021-12-02 Adrià Casamitjana , Marco Lorenzi , Sebastiano Ferraris , Loc Peter , Marc Modat , Allison Stevens , Bruce Fischl , Tom Vercauteren , Juan Eugenio Iglesias

Deformable image registration and regression are important tasks in medical image analysis. However, they are computationally expensive, especially when analyzing large-scale datasets that contain thousands of images. Hence, cluster…

计算机视觉与模式识别 · 计算机科学 2017-11-17 Zhipeng Ding , Greg Fleishman , Xiao Yang , Paul Thompson , Roland Kwitt , Marc Niethammer