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The emergence and development of cancer is a consequence of the accumulation over time of genomic mutations involving a specific set of genes, which provides the cancer clones with a functional selective advantage. In this work, we model…

机器学习 · 计算机科学 2017-03-10 Daniele Ramazzotti , Marco S. Nobile , Paolo Cazzaniga , Giancarlo Mauri , Marco Antoniotti

Bayesian inference is a powerful tool for combining information in complex settings, a task of increasing importance in modern applications. However, Bayesian inference with a flawed model can produce unreliable conclusions. This review…

统计方法学 · 统计学 2023-05-22 David J. Nott , Christopher Drovandi , David T. Frazier

Inverse problems arise almost everywhere in science and engineering where we need to infer on a quantity from indirect observation. The cases of medical, biomedical, and industrial imaging systems are the typical examples. A very high…

机器学习 · 计算机科学 2025-02-20 Ali Mohammad-Djafari

Black box neural networks are an indispensable part of modern robots. Nevertheless, deploying such high-stakes systems in real-world scenarios poses significant challenges when the stakeholders, such as engineers and legislative bodies,…

机器人学 · 计算机科学 2025-10-10 Som Sagar , Aditya Taparia , Harsh Mankodiya , Pranav Bidare , Yifan Zhou , Ransalu Senanayake

With the availability of large databases and recent improvements in deep learning methodology, the performance of AI systems is reaching or even exceeding the human level on an increasing number of complex tasks. Impressive examples of this…

人工智能 · 计算机科学 2017-08-29 Wojciech Samek , Thomas Wiegand , Klaus-Robert Müller

Deep neural networks (NNs) are powerful black box predictors that have recently achieved impressive performance on a wide spectrum of tasks. Quantifying predictive uncertainty in NNs is a challenging and yet unsolved problem. Bayesian NNs,…

机器学习 · 统计学 2017-11-07 Balaji Lakshminarayanan , Alexander Pritzel , Charles Blundell

We extend Probability Bracket Notation (PBN), inspired by the Dirac notation in quantum mechanics, to multivariable probability systems and static Bayesian networks (BNs). By defining probability distributions and conditional expectations…

人工智能 · 计算机科学 2026-05-12 Xing M. Wang

Bayesian Networks may be appealing for clinical decision-making due to their inclusion of causal knowledge, but their practical adoption remains limited as a result of their inability to deal with unstructured data. While neural networks do…

机器学习 · 计算机科学 2022-11-16 Paloma Rabaey , Cedric De Boom , Thomas Demeester

We developed the language of Modifiable Temporal Belief Networks (MTBNs) as a structural and temporal extension of Bayesian Belief Networks (BNs) to facilitate normative temporal and causal modeling under uncertainty. In this paper we…

人工智能 · 计算机科学 2013-02-18 Constantin F. Aliferis , Gregory F. Cooper

The application of Bayesian networks (BNs) to cognitive assessment and intelligent tutoring systems poses new challenges for model construction. When cognitive task analyses suggest constructing a BN with several latent variables, empirical…

人工智能 · 计算机科学 2013-01-18 David M. Williamson , Russell Almond , Robert Mislevy

Modern data analytics underpinned by machine learning techniques has become a key enabler to the automation of data-led decision making. As an important branch of state-of-the-art data analytics, business process predictions are also faced…

人工智能 · 计算机科学 2021-07-22 Chun Ouyang , Renuka Sindhgatta , Catarina Moreira

In this paper we examine the problem of inference in Bayesian Networks with discrete random variables that have very large or even unbounded domains. For example, in a domain where we are trying to identify a person, we may have variables…

人工智能 · 计算机科学 2012-12-12 Rita Sharma , David L Poole

A hybrid model involves the cooperation of an interpretable model and a complex black box. At inference, any input of the hybrid model is assigned to either its interpretable or complex component based on a gating mechanism. The advantages…

机器学习 · 计算机科学 2023-03-09 Julien Ferry , Gabriel Laberge , Ulrich Aïvodji

In many complex, real-world situations, problem solving and decision making require effective reasoning about causation and uncertainty. However, human reasoning in these cases is prone to confusion and error. Bayesian networks (BNs) are an…

Bayesian Neural Networks (BNNs) have recently received increasing attention for their ability to provide well-calibrated posterior uncertainties. However, model selection---even choosing the number of nodes---remains an open question. In…

机器学习 · 统计学 2017-05-31 Soumya Ghosh , Finale Doshi-Velez

Bayesian Neural Networks (BNNs) offer a principled and natural framework for proper uncertainty quantification in the context of deep learning. They address the typical challenges associated with conventional deep learning methods, such as…

统计计算 · 统计学 2024-11-13 Zahra Moslemi , Yang Meng , Shiwei Lan , Babak Shahbaba

As machine learning models and autonomous agents are increasingly deployed in high-stakes, real-world domains such as healthcare, security, finance, and robotics, the need for transparent and trustworthy explanations has become critical. To…

人工智能 · 计算机科学 2025-05-29 Haishi Bai , Jozo Dujmovic , Jianwu Wang

Artificial intelligence (AI) has huge potential to improve the health and well-being of people, but adoption in clinical practice is still limited. Lack of transparency is identified as one of the main barriers to implementation, as…

人工智能 · 计算机科学 2021-01-06 Aniek F. Markus , Jan A. Kors , Peter R. Rijnbeek

Conformal prediction has emerged as a cutting-edge methodology in statistics and machine learning, providing prediction intervals with finite-sample frequentist coverage guarantees. Yet, its interplay with Bayesian statistics, often…

统计方法学 · 统计学 2026-03-27 Nina Deliu , Brunero Liseo

Bayesian inference allows expressing the uncertainty of posterior belief under a probabilistic model given prior information and the likelihood of the evidence. Predominantly, the likelihood function is only implicitly established by a…