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Sepsis is a leading cause of death in the ICU. It is a disease requiring complex interventions in a short period of time, but its optimal treatment strategy remains uncertain. Evidence suggests that the practices of currently used treatment…

机器学习 · 计算机科学 2022-07-15 Zeyu Wang , Huiying Zhao , Peng Ren , Yuxi Zhou , Ming Sheng

Traditional Chinese medicine, as an essential component of traditional medicine, contains active ingredients that serve as a crucial source for modern drug development, holding immense therapeutic potential and development value. A…

机器学习 · 计算机科学 2025-05-02 Leifeng Zhang , Xin Dong , Shuaibing Jia , Jianhua Zhang

Engineering simulators used for steady-state multiphase pipe flows are commonly utilized to predict pressure drop. Such simulators are typically based on either empirical correlations or first-principles mechanistic models. The simulators…

数据分析、统计与概率 · 物理学 2019-06-04 Evgenii Kanin , Andrei Osiptsov , Albert Vainshtein , Evgeny Burnaev

In this study, we developed and tested machine learning models to predict epilepsy surgical outcome using noninvasive clinical and demographic data from patients. Methods: Seven dif-ferent categorization algorithms were used to analyze the…

Long-term chemical durability of glass, crucial for immobilizing nuclear waste, is governed by glass properties such as composition, surface geometry, as well as external factors like thermodynamic conditions and surrounding medium. Despite…

Metabolic (dysfunction) associated fatty liver disease (MAFLD) establishes new criteria for diagnosing fatty liver disease independent of alcohol consumption and concurrent viral hepatitis infection. However, the long-term outcome of MAFLD…

Machine Learning (ML) and Deep Learning (DL) based framework have evolved rapidly and generated considerable interests for predicting the properties of materials. In this work, we utilize ML-DL framework to predict the electrochemical…

Sepsis is a life-threatening condition triggered by an extreme infection response. Our objective is to forecast sepsis patient outcomes using their medical history and treatments, while learning interpretable state representations to assess…

机器学习 · 计算机科学 2023-11-17 Anna Wong , Shu Ge , Nassim Oufattole , Adam Dejl , Megan Su , Ardavan Saeedi , Li-wei H. Lehman

The in-vivo identification of the kidney stone types during an ureteroscopy would be a major medical advance in urology, as it could reduce the time of the tedious renal calculi extraction process, while diminishing infection risks.…

Diabetes is a chronic disease characterised by a high risk of developing diabetic nephropathy, which, in turn, is the leading cause of end-stage chronic kidney disease. The early identification of individuals at heightened risk of such…

定量方法 · 定量生物学 2024-09-24 Davide Dei Cas , Barbara Di Camillo , Gian Paolo Fadini , Giovanni Sparacino , Enrico Longato

Molecular docking is a structure-based computational drug design technique for predicting the interaction between a small molecule (ligand) and a macromolecule (receptor). Over the past three decades various docking software programs have…

定量方法 · 定量生物学 2023-10-18 Katherine Ge , Dayna Olson , Michel F. Sanner

Causal inference from electronic health records (EHR) is fundamentally limited by unmeasured confounding: critical clinical states such as frailty, goals of care, and mental status are documented in free-text notes but absent from…

机器学习 · 计算机科学 2026-04-22 Lei Liu , Jialin Chen , Kathy Macropol

One of the key requirements for incorporating machine learning into the drug discovery process is complete reproducibility and traceability of the model building and evaluation process. With this in mind, we have developed an end-to-end…

Global oil demand is rapidly increasing and is expected to reach 106.3 million barrels per day by 2040. Thus, it is vital for hydrocarbon extraction industries to forecast their production to optimize their operations and avoid losses. Big…

机器学习 · 计算机科学 2023-08-31 Siavash Hosseini , Thangarajah Akilan

Chemical design of SiO2-based glasses with high elastic moduli and low weight is of great interest. However, it is difficult to find a universal expression to predict the elastic moduli according to the glass composition before synthesis…

Liver transplant is an essential therapy performed for severe liver diseases. The fact of scarce liver resources makes the organ assigning crucial. Model for End-stage Liver Disease (MELD) score is a widely adopted criterion when making…

人工智能 · 计算机科学 2023-02-21 Sirui Ding , Ruixiang Tang , Daochen Zha , Na Zou , Kai Zhang , Xiaoqian Jiang , Xia Hu

Diabetes, especially T2DM, continues to be a significant health problem. One of the major concerns associated with diabetes is the development of its complications. Diabetic nephropathy, one of the chronic complication of diabetes,…

Cervical cancer, the fourth leading cause of cancer in women globally, requires early detection through Pap smear tests to identify precancerous changes and prevent disease progression. In this study, we performed a focused analysis by…

图像与视频处理 · 电气工程与系统科学 2025-05-22 Abdul Samad Shaik , Shashaank Mattur Aswatha , Rahul Jashvantbhai Pandya

Significant advancements in type 1 diabetes treatment have been made in the development of state-of-the-art Artificial Pancreas Systems (APS). However, lapses currently exist in the timely treatment of unsafe blood glucose (BG) levels,…

机器学习 · 计算机科学 2023-03-20 Chloe Smith , Maxfield Kouzel , Xugui Zhou , Homa Alemzadeh

Machine Learning Interatomic Potentials (MLIP) are a novel in silico approach for molecular property prediction, creating an alternative to disrupt the accuracy/speed trade-off of empirical force fields and density functional theory (DFT).…