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Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) are well-established techniques that provide valuable information in a diverse set of disciplines but are currently limited to macroscopic sample volumes. Here we…

Magnetic spin resonance is a key non-invasive sensing and imaging technique across the life-, material- and fundamental sciences with further medical and commercial applications. Recent advances using paramagnetic color centers enable…

介观与纳米尺度物理 · 物理学 2018-07-24 Florestan Ziem , Marwa Garsi , Helmut Fedder , Jörg Wrachtrup

The field of nanoscale magnetic resonance imaging (NanoMRI) was started 30 years ago. It was motivated by the desire to image single molecules and molecular assemblies, such as proteins and virus particles, with near-atomic spatial…

Magnetic resonance imaging (MRI) revolutionized diagnostic medicine and biomedical research by allowing a noninvasive access to spin ensembles. To enhance MRI resolution to the nanometer scale, new approaches including scanning probe…

介观与纳米尺度物理 · 物理学 2019-10-23 Philip Willke , Kai Yang , Yujeong Bae , Andreas J. Heinrich , Christopher P. Lutz

Magnetic resonance imaging (MRI) is the cornerstone technique for diagnostic medicine, biology, and neuroscience. This imaging method is highly innovative, noninvasive and its impact continues to grow. It can be used for measuring changes…

Molecular imaging refers to a class of noninvasive biomedical imaging techniques with the sensitivity and specificity to image biochemical variations in-vivo. An ideal molecular imaging technique visualizes a biochemical target according to…

医学物理 · 物理学 2013-04-03 Alex Hegyi , Eli Yablonovitch

Conventional nuclear magnetic resonance (NMR) spectroscopy relies on acquiring signal from a macroscopic ensemble of molecules to gain information about molecular structure and dynamics. Transferring this technique to nanoscale sample sizes…

介观与纳米尺度物理 · 物理学 2019-02-06 Jeffrey Holzgrafe , Qiushi Gu , Jan Beitner , Dhiren Kara , Helena S. Knowles , Mete Atatüre

Nanoscale magnetic resonance imaging (NanoMRI) is an active area of applied research with potential use in structural biology and quantum engineering. The success of this technological vision hinges on improving the instrument's sensitivity…

Microscopy enables detailed visualization and understanding of minute structures or processes. While cameras have significantly advanced optical, infrared, and electron microscopy, imaging nuclear magnetic resonance (NMR) signals on a…

We present a new method for high-resolution nanoscale magnetic resonance imaging (nano-MRI) that combines the high spin sensitivity of nanowire-based magnetic resonance detection with high spectral resolution nuclear magnetic resonance…

介观与纳米尺度物理 · 物理学 2018-03-07 William Rose , Holger Haas , Angela Q. Chen , Nari Jeon , Lincoln J. Lauhon , David G. Cory , Raffi Budakian

Magnetic Resonance Imaging (MRI) has become one of the most important tools to screen humans in medicine, virtually every modern hospital is equipped with an NMR tomograph. The potential of NMR in 3D imaging tasks is by far greater, but…

软凝聚态物质 · 物理学 2018-09-14 Ralf Stannarius

Nuclear magnetic resonance (NMR) imaging with nanometer resolution requires new detection techniques with sensitivity well beyond the capability of conventional inductive detection. Here, we demonstrate two dimensional imaging of $^1$H NMR…

介观与纳米尺度物理 · 物理学 2015-06-19 D. Rugar , H. J. Mamin , M. H. Sherwood , M. Kim , C. T. Rettner , K. Ohno , D. D. Awschalom

Magnetic Resonance Imaging (MRI) can characterize and discriminate among tissues using their diverse physical and biochemical properties. Unfortunately, submicrometer screening of biological specimens is presently not possible, mainly due…

介观与纳米尺度物理 · 物理学 2010-11-03 C. A. Meriles , L. Jiang , G. Goldstein , J. S. Hodges , J. R. Maze , M. D. Lukin , P. Cappellaro

Magnetic resonance imaging (MRI) has revolutionized biomedical science by providing non-invasive, three-dimensional biological imaging. However, spatial resolution in conventional MRI systems is limited to tens of microns, which is…

介观与纳米尺度物理 · 物理学 2015-06-18 M. S. Grinolds , M. Warner , K. De Greve , Y. Dovzhenko , L. Thiel , R. L. Walsworth , S. Hong , P. Maletinsky , A. Yacoby

Magnetic resonance imaging (MRI) is a widely used biomedical imaging modality that derives much of its contrast from microscale magnetic field gradients in biological tissues. However, the connection between these sub-voxel field patterns…

Magnetic resonance imaging (MRI) is the method of choice for noninvasive studies of micrometer-scale structures in biological tissues via their effects on the time/frequency-dependent ("restricted") and anisotropic self-diffusion of water.…

The implementation of nuclear magnetic resonance (NMR) at the nanoscale is a major challenge, as conventional systems require relatively large ensembles of spins and limit resolution to mesoscopic scales. New approaches based on quantum…

Nanomagnetometry using the nitrogen-vacancy (NV) centre in diamond has attracted a great deal of interest because of the combined features of room temperature operation, nanoscale resolution and high sensitivity. One of the important goals…

We demonstrate quantitative magnetic field mapping with nanoscale resolution, by applying a lock-in technique on the electron spin resonance frequency of a single nitrogen-vacancy defect placed at the apex of an atomic force microscope tip.…

介观与纳米尺度物理 · 物理学 2015-05-30 L. Rondin , J. -P. Tetienne , P. Spinicelli , C. Dal Savio , K. Karrai , G. Dantelle , A. Thiaville , S. Rohart , J. -F. Roch , V. Jacques

Optically-detected magnetic resonance using Nitrogen Vacancy (NV) color centres in diamond is a leading modality for nanoscale magnetic field imaging, as it provides single electron spin sensitivity, three-dimensional resolution better than…

介观与纳米尺度物理 · 物理学 2015-10-28 K. Arai , C. Belthangady , H. Zhang , N. Bar-Gill , S. J. DeVience , P. Cappellaro , A. Yacoby , R. L. Walsworth
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