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Ultrasound localization microscopy offers new radiation-free diagnostic tools for vascular imaging deep within the tissue. Sequential localization of echoes returned from inert microbubbles with low-concentration within the bloodstream…

医学物理 · 物理学 2018-04-11 Oren Solomon , Ruud J. G. van Sloun , Hessel Wijkstra , Massimo Mischi , Yonina C. Eldar

Ultrasound localization microscopy has enabled super-resolution vascular imaging through precise localization of individual ultrasound contrast agents (microbubbles) across numerous imaging frames. However, analysis of high-density regions…

信号处理 · 电气工程与系统科学 2018-12-14 Ruud J. G. van Sloun , Oren Solomon , Matthew Bruce , Zin Z. Khaing , Hessel Wijkstra , Yonina C. Eldar , Massimo Mischi

Ultrasound Localization Microscopy (ULM) offers a cost-effective modality for microvascular imaging by using intravascular contrast agents (microbubbles). However, ULM has a fundamental trade-off between acquisition time and spatial…

信号处理 · 电气工程与系统科学 2021-01-26 Ufuk Soylu , Yoram Bresler

Ultrasound Localization Microscopy can resolve the microvascular bed down to a few micrometers. To achieve such performance microbubble contrast agents must perfuse the entire microvascular network. Microbubbles are then located…

Super-resolution ultrasound can image microvascular structure and flow at sub-wave-diffraction resolution based on localising and tracking microbubbles. Currently, tracking microbubbles accurately under limited imaging frame rates and high…

图像与视频处理 · 电气工程与系统科学 2023-04-04 Biao Huang , Jipeng Yan , Megan Morris , Victoria Sinnett , Navita Somaiah , Meng-Xing Tang

Resolving arterial flows is essential for understanding cardiovascular pathologies, improving diagnosis, and monitoring patient condition. Ultrasound contrast imaging uses microbubbles to enhance the scattering of the blood pool, allowing…

Generation of super-resolution (SR) ultrasound (US) images, created from the successive local-ization of individual microbubbles in the circulation, has enabled the visualization of microvascular structure and flow at a level of detail that…

图像与视频处理 · 电气工程与系统科学 2024-06-19 Scott Schoen , Zhigen Zhao , Ashley Alva , Chengwu Huang , Shigao Chen , Costas Arvanitis

Recently, super-resolution ultrasound imaging with ultrasound localization microscopy (ULM) has received much attention. However, ULM relies on low concentrations of microbubbles in the blood vessels, ultimately resulting in long…

Super-Resolution Ultrasound (SRUS) imaging through localising and tracking microbubbles, also known as Ultrasound Localisation Microscopy (ULM), has demonstrated significant potential for reconstructing microvasculature and flows with…

图像与视频处理 · 电气工程与系统科学 2025-03-26 Jipeng Yan , Qingyuan Tan , Shusei Kawara , Jingwen Zhu , Bingxue Wang , Matthieu Toulemonde , Honghai Liu , Ying Tan , Meng-Xing Tang

Convection of liquid metals drives large natural processes and is important in technical processes. Model experiments are conducted for research purposes where simulations are expensive and the clarification of open questions requires novel…

流体动力学 · 物理学 2024-04-18 David Weik , Zehua Dou , Dirk Räbiger , Tobias Vogt , Sven Eckert , Jürgen Czarske , Lars Büttner

Identifying and visualizing vasculature within organs and tumors has major implications in managing cardiovascular diseases and cancer. Contrast-enhanced ultrasound scans detect slow-flowing blood, facilitating non-invasive perfusion…

医学物理 · 物理学 2018-09-18 Avinoam Bar-Zion , Oren Solomon , Charles Tremblay-Darveau , Dan Adam , Yonina C. Eldar

Ultrasound super-localization microscopy techniques presented in the last few years enable non-invasive imaging of vascular structures at the capillary level by tracking the flow of ultrasound contrast agents (gas microbubbles). However,…

组织与器官 · 定量生物学 2016-08-10 Avinoam Bar-Zion , Charles Tremblay-Darveau , Oren Solomon , Dan Adam , Yonina C. Eldar

High resolution transcranial ultrasound imaging in humans has been a persistent challenge for ultrasound due to the imaging degradation effects from aberration and reverberation. These mechanisms depend strongly on skull morphology and they…

医学物理 · 物理学 2018-11-28 Danai E. Soulioti , David Espíndola , Paul A. Dayton , Gianmarco Pinton

Super-resolution ultrasound (SRUS) imaging through localising and tracking sparse microbubbles has been shown to reveal microvascular structure and flow beyond the wave diffraction limit. Most SRUS studies use standard delay and sum (DAS)…

High frame rate 3-D ultrasound imaging technology combined with super-resolution processing method can visualize 3-D microvascular structures by overcoming the diffraction limited resolution in every spatial direction. However, 3-D…

The purpose of this study is to enable in-vivo three-dimensional (3-D) ultrasound localization microscopy (ULM) of posterior ocular microvasculature using a 256-channel system and a 1024-element matrix array, and to overcome limitations of…

Ultrasound Localization Microscopy (ULM) has recently enabled the mapping of the cerebral vasculature in vivo with a resolution ten times smaller than the wavelength used, down to ten microns. However, with frame rates up to 20.000 frames…

医学物理 · 物理学 2023-10-23 Erwan Hardy , Jonathan Poree , Hatim Belgharbi , Chloe Bourquin , Frederic Lesage , Jean Provost

Focused ultrasound stimulated microbubbles have been shown to be capable of inducing blood flow shutdown and necrosis in a range of tissue types in an approach termed antivascular ultrasound or mechanical ablation. In oncology, this…

医学物理 · 物理学 2022-10-17 Xiaoxiao Zhao , Carly Pellow , David E. Goertz

While the ultrasound and cavitation based therapies have mushroomed over the years, there is a lack of online monitoring the cavitation bubble dynamics in biological tissue. {\color{black}Here we demonstrate that with ultrasonic plane wave…

流体动力学 · 物理学 2023-05-26 S. Izak Ghasemian , F. Reuter , C. D. Ohl

The regulation of intestinal blood flow is critical to gastrointestinal function. Imaging the intestinal mucosal micro-circulation in vivo has the potential to provide new insight into the gut physiology and pathophysiology. We aimed to…

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