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Learning interpretable representations of neural dynamics at a population level is a crucial first step to understanding how observed neural activity relates to perception and behavior. Models of neural dynamics often focus on either…

机器学习 · 统计学 2025-01-13 Noga Mudrik , Yenho Chen , Eva Yezerets , Christopher J. Rozell , Adam S. Charles

Recent whole-brain calcium imaging recordings of the nematode C. elegans have demonstrated that neural activity is dominated by dynamics on a low-dimensional manifold that can be clustered according to behavioral states. Despite progress in…

神经元与认知 · 定量生物学 2020-02-05 Megan Morrison , Charles Fieseler , J. Nathan Kutz

Neural population activity often exhibits regime-dependent non-stationarity in the form of switching dynamics. Learning accurate switching dynamical system models can reveal how behavior is encoded in neural activity. Existing switching…

机器学习 · 计算机科学 2025-12-16 DongKyu Kim , Han-Lin Hsieh , Maryam M. Shanechi

Recordings of whole brain activity with single neuron resolution are now feasible in simple organisms. Yet, it is still challenging to appropriately simplify such complex, noisy, and multivariate data in order to reveal general principles…

神经元与认知 · 定量生物学 2017-11-27 Connor Brennan , Alex Proekt

Dynamic brain data, teeming with biological and functional insights, are becoming increasingly accessible through advanced measurements, providing a gateway to understanding the inner workings of the brain in living subjects. However, the…

神经元与认知 · 定量生物学 2025-08-19 Zixia Zhou , Junyan Liu , Wei Emma Wu , Ruogu Fang , Sheng Liu , Qingyue Wei , Rui Yan , Yi Guo , Qian Tao , Yuanyuan Wang , Md Tauhidul Islam , Lei Xing

Brains learn to represent information from a large set of stimuli, typically by weak supervision. Unsupervised learning is therefore a natural approach for exploring the design of biological neural networks and their computations.…

神经元与认知 · 定量生物学 2025-10-17 Roy Urbach , Elad Schneidman

Neural population activity relating to behaviour is assumed to be inherently low-dimensional despite the observed high dimensionality of data recorded using multi-electrode arrays. Therefore, predicting behaviour from neural population…

神经元与认知 · 定量生物学 2022-02-17 Justin Jude , Matthew G Perich , Lee E Miller , Matthias H Hennig

Neuromechanics aims to understand the link between an animal's neural activity and its physical behaviors. Recent advances in experimental and machine learning techniques enable simultaneous recordings of neural and locomotion dynamics over…

生物物理 · 物理学 2026-05-06 Alexander E. Cohen , Jörn Dunkel

Decoding stimuli or behaviour from recorded neural activity is a common approach to interrogate brain function in research, and an essential part of brain-computer and brain-machine interfaces. Reliable decoding even from small neural…

神经元与认知 · 定量生物学 2023-01-06 Justin Jude , Matthew G. Perich , Lee E. Miller , Matthias H. Hennig

In this paper, we propose a novel unsupervised learning method to learn the brain dynamics using a deep learning architecture named residual D-net. As it is often the case in medical research, in contrast to typical deep learning tasks, the…

机器学习 · 统计学 2019-03-01 Youngjoo Seo , Manuel Morante , Yannis Kopsinis , Sergios Theodoridis

Brain-wide recordings of large-scale networks of neurons now provide an unprecedented view into how the brain drives behavior. However, brain activity contains both information directly related to behavior as well as the potential for many…

神经元与认知 · 定量生物学 2026-05-06 Eva Yezerets , En Yang , Misha B. Ahrens , Adam S. Charles

The neural dynamics of the nematode C. elegans are experimentally low-dimensional and correspond to discrete behavioral states, where previous modeling work has found neural proxies for some of these states. Experimental results further…

神经元与认知 · 定量生物学 2015-09-04 James Kunert , Eli Shlizerman , Andrew Walker , J. Nathan Kutz

Speech encodes a wealth of information related to human behavior and has been used in a variety of automated behavior recognition tasks. However, extracting behavioral information from speech remains challenging including due to inadequate…

音频与语音处理 · 电气工程与系统科学 2021-04-09 Haoqi Li , Brian Baucom , Shrikanth Narayanan , Panayiotis Georgiou

We propose a method for learning dynamical systems from high-dimensional empirical data that combines variational autoencoders and (spatio-)temporal attention within a framework designed to enforce certain scientifically-motivated…

机器学习 · 计算机科学 2023-06-22 Kai Lagemann , Christian Lagemann , Sach Mukherjee

Neural manifolds are an attractive theoretical framework for characterizing the complex behaviors of neural populations. However, many of the tools for identifying these low-dimensional subspaces are correlational and provide limited…

神经元与认知 · 定量生物学 2025-08-12 Christof Fehrman , C. Daniel Meliza

The dynamics of complex systems generally include high-dimensional, non-stationary and non-linear behavior, all of which pose fundamental challenges to quantitative understanding. To address these difficulties we detail a new approach based…

定量方法 · 定量生物学 2020-09-11 Antonio Carlos Costa , Tosif Ahamed , Greg J. Stephens

Neural signals are characterized by rich temporal and spatiotemporal dynamics that reflect the organization of cortical networks. Theoretical research has shown how neural networks can operate at different dynamic ranges that correspond to…

神经元与认知 · 定量生物学 2017-07-05 Luca Ambrogioni , Marcel A. J. van Gerven , Eric Maris

There is overwhelming evidence that cognition, perception, and action rely on feedback control. However, if and how neural population dynamics are amenable to different control strategies is poorly understood, in large part because machine…

神经元与认知 · 定量生物学 2024-08-13 Ankit Kumar , Loren M. Frank , Kristofer E. Bouchard

Neural populations exhibit latent dynamical structures that drive time-evolving spiking activities, motivating the search for models that capture both intrinsic network dynamics and external unobserved influences. In this work, we introduce…

机器学习 · 计算机科学 2026-03-11 Yue Song , T. Anderson Keller , Yisong Yue , Pietro Perona , Max Welling

To fully understand, analyze, and determine the behavior of dynamical systems, it is crucial to identify their intrinsic modal coordinates. In nonlinear dynamical systems, this task is challenging as the modal transformation based on the…

机器学习 · 计算机科学 2025-03-13 Abdolvahhab Rostamijavanani , Shanwu Li , Yongchao Yang
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