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This study investigates the potential of multimodal data integration, which combines electroencephalogram (EEG) data with sociodemographic characteristics like age, sex, education, and intelligence quotient (IQ), to diagnose mental diseases…

Mental disorders present challenges in diagnosis and treatment due to their complex and heterogeneous nature. Electroencephalogram (EEG) has shown promise as a potential biomarker for these disorders. However, existing methods for analyzing…

统计方法学 · 统计学 2024-01-30 Xingche Guo , Bin Yang , Ji Meng Loh , Qinxia Wang , Yuanjia Wang

This work considers the problem of fitting functional models with sparsely and irregularly sampled functional data. It overcomes the limitations of the state-of-the-art methods, which face major challenges in the fitting of more complex…

统计方法学 · 统计学 2023-05-02 Aniruddha Rajendra Rao , Matthew Reimherr

Diagnosis of major depressive disorder (MDD) primarily relies on the patient's self-reported symptoms and a clinical evaluation. Effective connectivity (EC) from resting-state functional magnetic resonance imaging (rs-fMRI) analysis can…

神经元与认知 · 定量生物学 2024-01-01 Peishan Dai , Yun Shi , Tong Xiong , Xiaoyan Zhou , Shenghui Liao , Zhongchao Huang , Xiaoping Yi , Bihong T. Chen

The current-source density (CSD) analysis is a widely used method in brain electrophysiology, but this method rests on a series of assumptions, namely that the surrounding extracellular medium is resistive and uniform, and in some versions…

神经元与认知 · 定量生物学 2015-05-20 Claude Bedard , Alain Destexhe

To study the neurophysiological basis of attention deficit hyperactivity disorder (ADHD), clinicians use electroencephalography (EEG) which record neuronal electrical activity on the cortex. Instead of focusing on single-channel spectral…

应用统计 · 统计学 2025-06-16 Paolo Victor Redondo , Raphael Huser , Hernando Ombao

Functional brain imaging through electroencephalography (EEG) relies upon the analysis and interpretation of high-dimensional, spatially organized time series. We propose to represent time-localized frequency domain characterizations of EEG…

Missing values in electronic health record (EHR) data pose a significant challenge for epidemiologic research. Traditional methods for handling missing data, like mean imputation, may introduce bias. Multiple imputation (MI) offers a…

High-dimensional inference based on matrix-valued data has drawn increasing attention in modern statistical research, yet not much progress has been made in large-scale multiple testing specifically designed for analysing such data sets.…

统计方法学 · 统计学 2021-06-18 Xu Han , Sanat Sarkar , Shiyu Zhang

Depression is a widespread mental health disorder, yet its automatic detection remains challenging. Prior work has explored unimodal and multimodal approaches, with multimodal systems showing promise by leveraging complementary signals.…

人工智能 · 计算机科学 2026-03-24 Annisaa Fitri Nurfidausi , Eleonora Mancini , Paolo Torroni

We consider the problem of extracting features from passive, multi-channel electroencephalogram (EEG) devices for downstream inference tasks related to high-level mental states such as stress and cognitive load. Our proposed method…

信号处理 · 电气工程与系统科学 2022-03-02 Guodong Chen , Hayden S. Helm , Kate Lytvynets , Weiwei Yang , Carey E. Priebe

In this paper, we aimed at reviewing several different approaches present today in the search for more accurate diagnostic and treatment management in mental healthcare. Our focus is on mood disorders, and in particular on the major…

神经元与认知 · 定量生物学 2019-03-28 Milena Cukic Radenkovic

As a critical mental health disorder, depression has severe effects on both human physical and mental well-being. Recent developments in EEG-based depression analysis have shown promise in improving depression detection accuracies. However,…

机器学习 · 计算机科学 2025-11-18 Zhijian Gong , Wenjia Dong , Xueyuan Xu , Fulin Wei , Chunyu Liu , Li Zhuo

Depression is a common psychiatric disorder, which causes significant patient distress. Bipolar disorder is characterized by mood fluctuations between depression and mania. Unipolar and bipolar depression can be easily confused because of…

图像与视频处理 · 电气工程与系统科学 2019-09-02 Marie Zelenina , Diana Prata

Mobile technology enables unprecedented continuous monitoring of an individual's behavior, social interactions, symptoms, and other health conditions, presenting an enormous opportunity for therapeutic advancements and scientific…

Emerging evidence showed that major depressive disorder (MDD) is associated with disruptions of brain structural and functional networks, rather than impairment of isolated brain region. Thus, connectome-based models capable of predicting…

神经元与认知 · 定量生物学 2021-10-18 Aya Kabbara , Gabriel Robert , Mohamad Khalil , Marc Verin , Pascal Benquet , Mahmoud Hassan

Background: Depression has become a major health burden worldwide, and effective detection depression is a great public-health challenge. This Electroencephalography (EEG)-based research is to explore the effective biomarkers for depression…

信号处理 · 电气工程与系统科学 2020-02-26 Shuting Sun , Jianxiu Li , Huayu Chen , Tao Gong , Xiaowei Li , Bin Hu

Fatigue is a broad, multifactorial concept that includes the subjective perception of reduced physical and mental energy levels. It is also one of the key factors that strongly affect patients' health-related quality of life. To date, most…

人机交互 · 计算机科学 2021-08-10 Yang Bai , Yu Guan , Jian Qing Shi , Wan-Fai Ng

Biomarkers of Major Depressive Disorder(MDD), its phases and forms have long been sought. Research indicates that the complexity measures of the cortical electrical activity (EEG) might be candidates for this role. To examine whether the…

神经元与认知 · 定量生物学 2019-12-19 Čukić Milena , Stokić Miodrag , Radenković Slavoljub , Ljubisavljević Miloš , Simić Slobodan , Danka Savić

Clinical electroencephalography is routinely used to evaluate patients with diverse and often overlapping neurological conditions, yet interpretation remains manual, time-intensive, and variable across experts. While automated EEG analysis…

人机交互 · 计算机科学 2025-12-30 Argha Kamal Samanta , Deepak Mewada , Monalisa Sarma , Debasis Samanta
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