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A new paradigm is beginning to emerge in Radiology with the advent of increased computational capabilities and algorithms. This has led to the ability of real time learning by computer systems of different lesion types to help the…

Accurate recurrence risk stratification is crucial for optimizing treatment plans for breast cancer patients. Current prognostic tools like Oncotype DX (ODX) offer valuable genomic insights for HR+/HER2- patients but are limited by cost and…

图像与视频处理 · 电气工程与系统科学 2024-09-25 Ziyu Su , Yongxin Guo , Robert Wesolowski , Gary Tozbikian , Nathaniel S. O'Connell , M. Khalid Khan Niazi , Metin N. Gurcan

Predicting breast cancer recurrence risk is a critical clinical challenge. This study investigates the potential of computational pathology to stratify patients using deep learning on routine Hematoxylin and Eosin (H&E) stained whole-slide…

计算机视觉与模式识别 · 计算机科学 2025-12-23 Jinqiu Chen , Huyan Xu

Background and Aim: Recently, deep learning using convolutional neural network has been used successfully to classify the images of breast cells accurately. However, the accuracy of manual classification of those histopathological images is…

图像与视频处理 · 电气工程与系统科学 2021-08-11 Ashu Thapa , Abeer Alsadoon , P. W. C. Prasad , Simi Bajaj , Omar Hisham Alsadoon , Tarik A. Rashid , Rasha S. Ali , Oday D. Jerew

Artificial intelligence methods including deep neural networks (DNN) can provide rapid molecular classification of tumors from routine histology with accuracy that matches or exceeds human pathologists. Discerning how neural networks make…

Breast cancer ranks as the most prevalent form of cancer diagnosed in women, and diagnosis faces several challenges, a change in the size, shape and appearance of breasts, dense breast tissue, lumps or thickening in the breast especially if…

图像与视频处理 · 电气工程与系统科学 2023-12-12 Abdulqader Mohammed , Mohammed Abdel Razek , Mohamed El-dosuky , Ahmed Sobhi

Deep convolutional neural networks (CNNs) have emerged as a new paradigm for Mammogram diagnosis. Contemporary CNN-based computer-aided-diagnosis (CAD) for breast cancer directly extract latent features from input mammogram image and ignore…

图像与视频处理 · 电气工程与系统科学 2020-08-13 Heyi Li , Dongdong Chen , William H. Nailon , Mike E. Davies , David Laurenson

Accurate breast cancer diagnosis through mammography has the potential to save millions of lives around the world. Deep learning (DL) methods have shown to be very effective for mass detection in mammograms. Additional improvements of…

计算机视觉与模式识别 · 计算机科学 2022-07-25 Adarsh Sehgal , Muskan Sehgal , Hung Manh La , George Bebis

Composed of amino acid chains that influence how they fold and thus dictating their function and features, proteins are a class of macromolecules that play a central role in major biological processes and are required for the structure,…

定量方法 · 定量生物学 2022-07-15 Aaron Wang

BACKGROUND: Breast cancer has emerged as one of the most prevalent cancers among women leading to a high mortality rate. Due to the heterogeneous nature of breast cancer, there is a need to identify differentially expressed genes associated…

机器学习 · 计算机科学 2021-11-30 Sheetal Rajpal , Ankit Rajpal , Manoj Agarwal , Naveen Kumar

Effective surgical planning for breast cancer hinges on accurately predicting pathological complete response (pCR) to neoadjuvant chemotherapy (NAC). Diffusion-weighted MRI (DWI) and machine learning offer a non-invasive approach for early…

计算机视觉与模式识别 · 计算机科学 2024-04-09 Shir Nitzan , Maya Gilad , Moti Freiman

There is an increasing interest in the use of Deep Learning (DL) based methods as a supporting analytical framework in oncology. However, most direct applications of DL will deliver models with limited transparency and explainability, which…

定量方法 · 定量生物学 2023-01-26 Magdalena Wysocka , Oskar Wysocki , Marie Zufferey , Dónal Landers , André Freitas

We propose a new methodology for selecting and ranking covariates associated with a variable of interest in a context of high-dimensional data under dependence but few observations. The methodology successively intertwines the clustering of…

Prevention and early diagnosis of breast cancer (BC) is an essential prerequisite for the selection of proper treatment. The substantial pressure due to the increase of demand for faster and more precise diagnostic results drives for…

图像与视频处理 · 电气工程与系统科学 2021-06-29 Peter Bokor , Lukas Hudec , Ondrej Fabian , Wanda Benesova

Gene selection plays a pivotal role in oncology research for improving outcome prediction accuracy and facilitating cost-effective genomic profiling for cancer patients. This paper introduces two gene selection strategies for deep…

基因组学 · 定量生物学 2024-03-05 Akhila Krishna , Ravi Kant Gupta , Pranav Jeevan , Amit Sethi

The accurate diagnosis of pathological subtypes of lung cancer is of paramount importance for follow-up treatments and prognosis managements. Assessment methods utilizing deep learning technologies have introduced novel approaches for…

图像与视频处理 · 电气工程与系统科学 2024-07-19 Yuan Jin , Gege Ma , Geng Chen , Tianling Lyu , Jan Egger , Junhui Lyu , Shaoting Zhang , Wentao Zhu

Breast ultrasound (US) is an effective imaging modality for breast cancer detection and diagnosis. US computer-aided diagnosis (CAD) systems have been developed for decades and have employed either conventional hand-crafted features or…

医学物理 · 物理学 2020-03-12 Erlei Zhang , Stephen Seiler , Mingli Chen , Weiguo Lu , Xuejun Gu

Deep Learning has a hierarchical network architecture to represent the complicated feature of input patterns. The adaptive structural learning method of Deep Belief Network (DBN) has been developed. The method can discover an optimal number…

神经与进化计算 · 计算机科学 2018-08-28 Shin Kamada , Takumi Ichimura , Toshihide Harada

Current analysis of tumor proliferation, the most salient prognostic biomarker for invasive breast cancer, is limited to subjective mitosis counting by pathologists in localized regions of tissue images. This study presents the first…

计算机视觉与模式识别 · 计算机科学 2016-10-12 Manan Shah , Christopher Rubadue , David Suster , Dayong Wang

With recent advancements in the development of artificial intelligence applications using theories and algorithms in machine learning, many accurate models can be created to train and predict on given datasets. With the realization of the…

机器学习 · 计算机科学 2024-03-29 Pei Xi , Lin