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Time-resolved photon-counting plays an indispensable role in precision metrology in both classical and quantum regimes. In particular, time-correlated single-photon counting (TCSPC) has been the key enabling technology for applications such…

光学 · 物理学 2021-10-29 Bowen Li , Jan Bartos , Yijun Xie , Shu-Wei Huang

Purpose: The purpose of this work was to provide a flexible platform for FLASH research with protons by adapting a former clinical pencil beam scanning gantry to irradiations with ultrahigh dose rates. Methods: PSI Gantry 1 treated patients…

Charged particle beams are used in Particle Therapy (PT) to treat oncological patients due to their selective dose deposition in tissues and to their high biological effect in killing cancer cells with respect to photons and electrons used…

We present results of a toy model study of performance of the Time-of-Flight detectors integrated into forward proton detectors. The goal of the ToF device is to suppress effects of additional soft processes (so called pile-up) accompanying…

高能物理 - 唯象学 · 物理学 2021-01-29 Karel Černý , Marek Taševský , Tomáš Sýkora , Radek Žlebčík

Time of Flight (ToF) is a prevalent depth sensing technology in the fields of robotics, medical imaging, and non-destructive testing. Yet, ToF sensing faces challenges from complex ambient conditions making an inverse modelling from the…

计算机视觉与模式识别 · 计算机科学 2023-12-27 Christopher Hahne , Michel Hayoz , Raphael Sznitman

Aim: Investigate whether a time walk assessment derived from crystal light sharing and multi-photon time stamps can improved the TOF resolution. Method: Monte Carlo simulations were performed for SiPM (FBK-NUV-HD) coupled to conventional…

仪器与探测器 · 物理学 2020-10-12 Stephan Walrand , Michel Hesse , François Jamar

Long-distance depth imaging holds great promise for applications such as autonomous driving and robotics. Direct time-of-flight (dToF) imaging offers high-precision, long-distance depth sensing, yet demands ultra-short pulse light sources…

计算机视觉与模式识别 · 计算机科学 2025-05-29 Manchao Bao , Shengjiang Fang , Tao Yue , Xuemei Hu

In recent years, computational Time-of-Flight (ToF) imaging has emerged as an exciting and a novel imaging modality that offers new and powerful interpretations of natural scenes, with applications extending to 3D, light-in-flight, and…

图像与视频处理 · 电气工程与系统科学 2024-11-05 Ruiming Guo , Ayush Bhandari

Purpose: The FLASH effect, which reduces the radiosensitivity of healthy tissue while maintaining tumor control at high dose rates, has shown potential for improving radiation therapy. Conformal FLASH proton therapy involves advanced…

医学物理 · 物理学 2023-04-13 Sylvain Deffet , Edmond Sterpin

The aim of this work is to show the potential capabilities of monolithic crystals coupled to large SiPM arrays, to be considered as detector blocks for PET scanners enabling Time Of Flight (TOF) capabilities. Monolithic blocks allow one to…

We aim to investigate the feasibility of online monitoring of irradiation time (IRT) and scan time for FLASH radiotherapy using a pixelated semiconductor detector. Measurements of the time structure of FLASH irradiations were performed…

The EndoTOFPET-US project aims to jointly exploit Time-Of-Flight Positron Emission Tomography (TOFPET) and ultrasound endoscopy with a multi-modal instrument for the development of new biomarkers for pancreas and prostate oncology. The…

仪器与探测器 · 物理学 2013-03-20 Erika Garutti

The interplay between the beam delivery time structure and the patient motion makes 4D dose calculation (4DDC) important when treating moving tumors with intensity modulated proton therapy. 4DDC based on phase sorting of a 4DCT suffers from…

医学物理 · 物理学 2023-10-13 Ivar Bengtsson , Erik Engwall , Albin Fredriksson , Lars Glimelius

The new CDFII detector incorporates a Time-of-Flight detector (TOF), employing plastic scintillator bars and fine-mesh photomultipliers. Since August 2001 the TOF system has been fully instrumented and integrated into the CDFII data…

Proton therapy provides superior dose conformity compared with photon radiotherapy, concentrating radiation within the tumor while sparing adjacent healthy tissue. This advantage has been most effectively realized for static tumors in…

医学物理 · 物理学 2025-10-09 Vivek Maradia , Nick Yue , Adam Molzahn , Jingqian Wang , Mark Pankuch , Serdar Charyyev , Billy W. Loo

Depth cameras are emerging as a cornerstone modality with diverse applications that directly or indirectly rely on measured depth, including personal devices, robotics, and self-driving vehicles. Although time-of-flight (ToF) methods have…

计算机视觉与模式识别 · 计算机科学 2021-05-26 Seung-Hwan Baek , Noah Walsh , Ilya Chugunov , Zheng Shi , Felix Heide

We have developed a novel detector, referred to as an "$\alpha$-ToF detector", for correlated measurements of atomic masses and decay properties of low-yield, short-lived radioactive isotopes using a multi-reflection time-of-flight mass…

Active breath-hold techniques effectively mitigate respiratory motion but pose challenges for patients who are ineligible for the procedure. Conventional treatment planning relies on multiple energy layers, extending delivery time due to…

医学物理 · 物理学 2025-02-04 Ahmal Jawad Zafar , Xiaofeng Yang , Yinan Wang , Zachary Diamond , Jun Zhou

Radiotherapy is one of the main methods in the successful treatment of cancer. The tumor is irradiated with photons or charged particles (e.g. protons), and in the case of massive charged particles, the treatment results in less unnecessary…

医学物理 · 物理学 2019-03-20 Monika Varga-Kofarago

Purpose: To demonstrate a proton imaging system based on well-established fast scintillator technology to achieve high performance with low cost and complexity, with the potential of a straightforward translation into clinical use. Methods:…