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Synaptic connections in neuronal circuits are modulated by pre- and post-synaptic spiking activity. Heuristic models of this process of synaptic plasticity can provide excellent fits to results from in-vitro experiments in which pre- and…

神经元与认知 · 定量生物学 2022-07-14 Federico Devalle , Alex Roxin

Neurons in a micro-circuit connected by chemical synapses can have their connectivity affected by the prior activity of the cells. The number of synapses available for releasing neurotransmitter can be decreased by repetitive activation…

神经元与认知 · 定量生物学 2018-04-09 Elham Bayat Mokhtari , J. Josh Lawrence , Emily F Stone

How can neural networks learn to efficiently represent complex and high-dimensional inputs via local plasticity mechanisms? Classical models of representation learning assume that input weights are learned via pairwise Hebbian-like…

神经元与认知 · 定量生物学 2022-10-04 Fabian Alexander Mikulasch , Lucas Rudelt , Viola Priesemann

In neural circuits, synaptic strengths influence neuronal activity by shaping network dynamics, and neuronal activity influences synaptic strengths through activity-dependent plasticity. Motivated by this fact, we study a recurrent-network…

神经元与认知 · 定量生物学 2024-01-12 David G. Clark , L. F. Abbott

A theory of temporally asymmetric Hebb (TAH) rules which depress or potentiate synapses depending upon whether the postsynaptic cell fires before or after the presynaptic one is presented. Using the Fokker-Planck formalism, we show that the…

无序系统与神经网络 · 物理学 2009-10-31 Jonathan Rubin , Daniel D. Lee , H. Sompolinsky

Brain plasticity refers to brain's ability to change neuronal connections, as a result of environmental stimuli, new experiences, or damage. In this work, we study the effects of the synaptic delay on both the coupling strengths and…

Short-term presynaptic plasticity designates variations of the amplitude of synaptic information transfer whereby the amount of neurotransmitter released upon presynaptic stimulation changes over seconds as a function of the neuronal firing…

神经元与认知 · 定量生物学 2011-12-06 Maurizio De Pittà , Vladislav Volman , Hugues Berry , Eshel Ben-Jacob

Recent evidence in rodent cerebral cortex and olfactory bulb suggests that short-term dynamics of excitatory synaptic transmission is correlated to stereotypical connectivity motifs. It was observed that neurons with short-term facilitating…

神经元与认知 · 定量生物学 2016-04-08 Eleni Vasilaki , Michele Giugliano

Experimental observations on synaptic plasticity at individual glutamatergic synapses from the CA3 Shaffer collateral pathway onto CA1 pyramidal cells in the hippocampus suggest that the transitions in synaptic strength occur among discrete…

定量方法 · 定量生物学 2013-04-26 H. D. Abarbanel , S. S. Talathi , L. Gibb , M. Rabinovich

Many mathematical models of synaptic plasticity have been proposed to explain the diversity of plasticity phenomena observed in biological organisms. These models range from simple interpretations of Hebb's postulate, which suggests that…

神经元与认知 · 定量生物学 2025-08-05 Danil Tyulmankov

The plasticity property of biological neural networks allows them to perform learning and optimize their behavior by changing their configuration. Inspired by biology, plasticity can be modeled in artificial neural networks by using Hebbian…

神经与进化计算 · 计算机科学 2020-12-21 Anil Yaman , Giovanni Iacca , Decebal Constantin Mocanu , George Fletcher , Mykola Pechenizkiy

Synapses change on multiple timescales, ranging from milliseconds to minutes, due to a combination of both short- and long-term plasticity. Here we develop an extension of the common Generalized Linear Model to infer both short- and…

神经元与认知 · 定量生物学 2022-08-15 Ganchao Wei , Ian H. Stevenson

We investigate spike-timing dependent plasticity (STPD) in the case of a synapse connecting two neural cells. We develop a theoretical analysis of several STDP rules using Markovian theory. In this context there are two different…

神经元与认知 · 定量生物学 2021-11-16 Philippe Robert , Gaëtan Vignoud

Priming is the ability of the brain to more quickly activate a target concept in response to a related stimulus (prime). Experiments point to the existence of an overlap between the populations of the neurons coding for different stimuli.…

适应与自组织系统 · 物理学 2016-11-15 Pascal Chossat , Martin Krupa , Frédéric Lavigne

Synaptic connections are known to change dynamically. High-frequency presynaptic inputs induce decrease of synaptic weights. This process is known as short-term synaptic depression. The synaptic depression controls a gain for presynaptic…

无序系统与神经网络 · 物理学 2007-05-23 Narihisa Matsumoto , Daisuke Ide , Masataka Watanabe , Masato Okada

Correlation-based Hebbian plasticity is thought to shape neuronal connectivity during development and learning, whereas homeostatic plasticity would stabilize network activity. Here we investigate another, new aspect of this dichotomy: Can…

神经元与认知 · 定量生物学 2018-03-02 Júlia V Gallinaro , Stefan Rotter

Cortical populations of neurons develop sparse representations adapted to the statistics of the environment. While existing synaptic plasticity models reproduce some of the observed receptive-field properties, a major obstacle is the…

神经元与认知 · 定量生物学 2022-09-16 Carlos Stein N. Brito , Wulfram Gerstner

We present a novel stochastic Hebb-like learning rule for neural networks. This learning rule is stochastic with respect to the selection of the time points when a synaptic modification is induced by pre- and postsynaptic activation.…

无序系统与神经网络 · 物理学 2007-05-23 Frank Emmert-Streib

We theoretically investigate long-term potentiation (LTP) in the hippocampus using a simple model of a neuron stimulated by three different time-structured input signals (regular, Markov, and chaotic). The synaptic efficacy change is…

无序系统与神经网络 · 物理学 2009-10-30 M. Tatsuno , Y. Aizawa

This study proposes voltage-dependent-synaptic plasticity (VDSP), a novel brain-inspired unsupervised local learning rule for the online implementation of Hebb's plasticity mechanism on neuromorphic hardware. The proposed VDSP learning rule…

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