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Lipid nanoparticles (LNPs) are highly effective carriers for gene therapies, including mRNA and siRNA delivery, due to their ability to transport nucleic acids across biological membranes, low cytotoxicity, improved pharmacokinetics, and…

生物大分子 · 定量生物学 2025-06-06 Gaurav Kumar , Arezoo M. Ardekani

Semiparametric regression offers a flexible framework for modeling non-linear relationships between a response and covariates. A prime example are generalized additive models where splines (say) are used to approximate non-linear functional…

统计理论 · 数学 2018-10-05 Francis K. C. Hui , Chong You , Han Lin Shang , Samuel Müller

Supervised contour detection methods usually require many labeled training images to obtain satisfactory performance. However, a large set of annotated data might be unavailable or extremely labor intensive. In this paper, we investigate…

计算机视觉与模式识别 · 计算机科学 2016-05-18 Zizhao Zhang , Fuyong Xing , Xiaoshuang Shi , Lin Yang

We introduce 'semi-unsupervised learning', a problem regime related to transfer learning and zero-shot learning where, in the training data, some classes are sparsely labelled and others entirely unlabelled. Models able to learn from…

机器学习 · 统计学 2018-12-12 Matthew Willetts , Aiden Doherty , Stephen Roberts , Chris Holmes

Quantum Machine Learning (QML) continues to evolve, unlocking new opportunities for diverse applications. In this study, we investigate and evaluate the applicability of QML models for binary classification of genome sequence data by…

机器学习 · 计算机科学 2025-01-15 Navneet Singh , Shiva Raj Pokhrel

A new type of experiment that aims to determine the optimal quantities of a sequence of factors is eliciting considerable attention in medical science, bioengineering, and many other disciplines. Such studies require the simultaneous…

统计方法学 · 统计学 2022-09-14 Qian Xiao , Yaping Wang , Abhyuday Mandal , Xinwei Deng

The need for a large amount of labeled data in the supervised setting has led recent studies to utilize self-supervised learning to pre-train deep neural networks using unlabeled data. Many self-supervised training strategies have been…

计算机视觉与模式识别 · 计算机科学 2022-04-06 Mojtaba Bahrami , Mahsa Ghorbani , Nassir Navab

Self-Attention Mechanism (SAM) excels at distilling important information from the interior of data to improve the computational efficiency of models. Nevertheless, many Quantum Machine Learning (QML) models lack the ability to distinguish…

量子物理 · 物理学 2023-10-13 Ren-Xin Zhao , Jinjing Shi , Xuelong Li

Tensor networks are efficient representations of high-dimensional tensors which have been very successful for physics and mathematics applications. We demonstrate how algorithms for optimizing such networks can be adapted to supervised…

机器学习 · 统计学 2017-05-22 E. Miles Stoudenmire , David J. Schwab

Successful Human-Robot collaboration requires a predictive model of human behavior. The robot needs to be able to recognize current goals and actions and to predict future activities in a given context. However, the spatio-temporal sequence…

计算机视觉与模式识别 · 计算机科学 2018-09-20 Judith Bütepage , Danica Kragic

The analysis of complex computer simulations, often involving functional data, presents unique statistical challenges. Conventional regression methods, such as function-on-function regression, typically associate functional outcomes with…

统计方法学 · 统计学 2026-02-11 R. Jacob Andros , Rajarshi Guhaniyogi , Devin Francom , Donatella Pasqualini

We provide guarantees for learning latent variable models emphasizing on the overcomplete regime, where the dimensionality of the latent space can exceed the observed dimensionality. In particular, we consider multiview mixtures, spherical…

机器学习 · 计算机科学 2014-12-18 Animashree Anandkumar , Rong Ge , Majid Janzamin

Neural network based generative models with discriminative components are a powerful approach for semi-supervised learning. However, these techniques a) cannot account for model uncertainty in the estimation of the model's discriminative…

机器学习 · 统计学 2017-06-30 Jonathan Gordon , José Miguel Hernández-Lobato

To address the annotation burden in LiDAR-based 3D object detection, active learning (AL) methods offer a promising solution. However, traditional active learning approaches solely rely on a small amount of labeled data to train an initial…

计算机视觉与模式识别 · 计算机科学 2025-03-25 Zengran Wang , Yanan Zhang , Jiaxin Chen , Di Huang

In many modern machine learning applications, the outcome is expensive or time-consuming to collect while the predictor information is easy to obtain. Semi-supervised learning (SSL) aims at utilizing large amounts of `unlabeled' data along…

统计方法学 · 统计学 2017-11-16 Jessica Gronsbell , Tianxi Cai

A key challenge with controlling complex dynamical systems is to accurately model them. However, this requirement is very hard to satisfy in practice. Data-driven approaches such as Gaussian processes (GPs) have proved quite effective by…

机器人学 · 计算机科学 2022-03-08 Mouhyemen Khan , Akash Patel , Abhijit Chatterjee

To predict rare extreme events using deep neural networks, one encounters the so-called small data problem because even long-term observations often contain few extreme events. Here, we investigate a model-assisted framework where the…

机器学习 · 计算机科学 2022-04-20 Anna Asch , Ethan Brady , Hugo Gallardo , John Hood , Bryan Chu , Mohammad Farazmand

Propagating input uncertainty through non-linear Gaussian process (GP) mappings is intractable. This hinders the task of training GPs using uncertain and partially observed inputs. In this paper we refer to this task as "semi-described…

机器学习 · 统计学 2015-09-04 Andreas Damianou , Neil D. Lawrence

One of the challenges in developing deep learning algorithms for medical image segmentation is the scarcity of annotated training data. To overcome this limitation, data augmentation and semi-supervised learning (SSL) methods have been…

图像与视频处理 · 电气工程与系统科学 2020-09-02 Bram Ruijsink , Esther Puyol-Anton , Ye Li , Wenja Bai , Eric Kerfoot , Reza Razavi , Andrew P. King

We present a modelling framework for the investigation of supervised learning in non-stationary environments. Specifically, we model two example types of learning systems: prototype-based Learning Vector Quantization (LVQ) for…

机器学习 · 计算机科学 2021-04-30 Michiel Straat , Fthi Abadi , Zhuoyun Kan , Christina Göpfert , Barbara Hammer , Michael Biehl