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Imaging features of knee articular cartilage have been shown to be potential imaging biomarkers for knee osteoarthritis. Despite recent methodological advancements in image analysis techniques like image segmentation, registration, and…

图像与视频处理 · 电气工程与系统科学 2024-09-12 Yongcheng Yao , Weitian Chen

Articular cartilage showcases distinctive mechanical behaviour, attributable to its biphasic composition and hierarchical organization. Proteoglycans, essential constituents of the extracellular matrix, contribute to tissue swelling,…

医学物理 · 物理学 2025-10-24 S. Fantoni , M. Berni , R. Fognani , G. Fraterrigo , P. Cardarelli , F. Baruffaldi , M. Baleani

Knee osteoarthritis (OA) is the most common osteoarthritis and a leading cause of disability. Cartilage defects are regarded as major manifestations of knee OA, which are visible by magnetic resonance imaging (MRI). Thus early detection and…

图像与视频处理 · 电气工程与系统科学 2022-01-13 Zixu Zhuang , Liping Si , Sheng Wang , Kai Xuan , Xi Ouyang , Yiqiang Zhan , Zhong Xue , Lichi Zhang , Dinggang Shen , Weiwu Yao , Qian Wang

The degeneration of articular cartilage (AC) occurs in osteoarthritis (OA), which is a leading cause of pain and disability in middle-aged and older people. The early disease related changes in cartilage extra-cellular matrix (ECM) start…

Articular cartilage is a musculoskeletal soft tissue renowned for its unique mechanical properties. Understanding both its hierarchical structure and the interplay between its constituents could shed light on the mechanical competence of…

医学物理 · 物理学 2025-10-17 Simone Fantoni , Luca Brombal , Paolo Cardarelli , Fabio Baruffaldi

Cardiovascular disease is a major life-threatening condition that is commonly monitored using electrocardiogram (ECG) signals. However, these signals are often contaminated by various types of noise at different intensities, significantly…

信号处理 · 电气工程与系统科学 2024-07-17 Ding Zhu , Vishnu Kabir Chhabra , Mohammad Mahdi Khalili

Advancements in wireless ultrasound technology allow for point of care cartilage imaging, yet validation against traditional ultrasound units remains to be established for knee cartilage outcomes. Therefore, the purpose of our study was to…

图像与视频处理 · 电气工程与系统科学 2024-05-21 Arjun Parmar , Corey D Grozier , Robert Dima , Jessica E Tolzman , Ilker Hacihaliloglu , Kenneth L Cameron , Ryan Fajardo , Matthew S Harkey

Healthy articular cartilage, covering the ends of bones in major joints such as hips and knees, presents the most efficiently-lubricated surface known in nature, with friction coefficients as low as 0.001 up to physiologically high…

医学物理 · 物理学 2023-11-07 Weifeng Lin , Jacob Klein

Background: MRI is the modality of choice for cartilage imaging; however, its diagnostic performance is variable and significantly lower than the gold standard diagnostic knee arthroscopy. In recent years, deep learning has been used to…

计算机视觉与模式识别 · 计算机科学 2021-06-24 Gergo Merkely , Alireza Borjali , Molly Zgoda , Evan M. Farina , Simon Gortz , Orhun Muratoglu , Christian Lattermann , Kartik M. Varadarajan

The integrity of articular cartilage is a crucial aspect in the early diagnosis of osteoarthritis (OA). Many novel MRI techniques have the potential to assess compositional changes of the cartilage extracellular matrix. Among these…

计算机视觉与模式识别 · 计算机科学 2019-12-05 Alejandra Duarte , Chaitra V. Hegde , Aakash Kaku , Sreyas Mohan , José G. Raya

Significance: Non-invasive determination of structural changes in articular cartilage immediately after impact and rehydration provides insight into the response and recovery of the soft tissue, as well as provides a potential methodology…

医学物理 · 物理学 2020-08-04 Matthew Goodwin , Joshua Workman , Ashvin Thambyah , Frédérique Vanholsbeeck

Cartilage is a connective tissue that covers the surfaces of bones in joints and provides a smooth gliding surface for movement. It is characterized by specific biophysical properties that allow it to withstand compressive loads, distribute…

医学物理 · 物理学 2023-05-03 Enrico Catalano

Photoacoustic imaging of interphalangeal peripheral joints is of interest in the context of using the synovial membrane as a surrogate marker of rheumatoid arthritis. Previous work has shown that ultrasound produced by absorption of light…

医学物理 · 物理学 2015-06-09 Samir Biswas , Peter van Es , Wiendelt Steenbergen , Srirang Manohar

High Frequency Oscillations (HFOs), rapid bursts of brain activity above 80 Hz, have emerged as a highly specific biomarker for epileptogenic tissue. Recent evidence suggests that HFOs are also present in Alzheimer's Disease (AD),…

信号处理 · 电气工程与系统科学 2026-01-13 Samin Yaser , Mahad Ali , Yang Jiang , Phuc Nguyen , Jing Xiang , Laura J. Brattain

Ultrasound is widely used in medical diagnostics allowing for accessible and powerful imaging but suffers from resolution limitations due to diffraction and the finite aperture of the imaging system, which restricts diagnostic use. The…

计算机视觉与模式识别 · 计算机科学 2024-08-08 Felix Duelmer , Walter Simson , Mohammad Farid Azampour , Magdalena Wysocki , Angelos Karlas , Nassir Navab

Analyzing knee cartilage thickness and strain under load can help to further the understanding of the effects of diseases like Osteoarthritis. A precise segmentation of the cartilage is a necessary prerequisite for this analysis. This…

Ultrasound wave propagation in a nonhomogeneous linearly elastic layer of constant thickness is considered. The resonances for the corresponding acoustic propagator are studied. It is shown that the distribution of the resonances depends on…

数学物理 · 物理学 2012-02-06 Ivan Argatov , Alexei Iantchenko

Ultrasound imaging is generally employed for real-time investigation of internal anatomy of the human body for disease identification. Delineation of the anatomical boundary of organs and pathological lesions is quite challenging due to the…

计算机视觉与模式识别 · 计算机科学 2019-01-23 Sumanth Nandamuri , Debarghya China , Pabitra Mitra , Debdoot Sheet

Osteoarthritis (OA), a chronic disease characterized by articular cartilage degeneration, is a leading cause of disability and pain worldwide. In OA, chondrocytes in cartilage undergo phenotypic changes and senescence, restricting cartilage…

Studying the morphological development of cartilaginous and osseous structures is critical to the early detection of life-threatening skeletal dysmorphology. Embryonic cartilage undergoes rapid structural changes within hours, introducing…

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