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The problem of maximizing cell type discovery under budget constraints is a fundamental challenge for the collection and analysis of single-cell RNA-sequencing (scRNA-seq) data. In this paper, we introduce a simple, computationally…

We consider chance constrained optimization where it is sought to optimize a function while complying with constraints, both of which are affected by uncertainties. The high computational cost of realistic simulations strongly limits the…

We consider the problem of boundary detection for areal data, focusing on situations where for each areal unit multiple observations are available. We propose a Bayesian nonparametric mixture model for the area-specific population…

统计方法学 · 统计学 2026-05-18 Matteo Gianella , Mario Beraha , Alessandra Guglielmi

In this work we explore a straightforward variational Bayes scheme for Recurrent Neural Networks. Firstly, we show that a simple adaptation of truncated backpropagation through time can yield good quality uncertainty estimates and superior…

机器学习 · 计算机科学 2019-05-13 Meire Fortunato , Charles Blundell , Oriol Vinyals

A novel data-driven methodology is presented for the joint selection of prior parameters for both fixed and random effects in Linear Mixed Models (LMMs). This approach facilitates the estimation of complex random-effects structures, as well…

统计方法学 · 统计学 2026-04-28 Matteo Amestoy , R. Vermeulen , Mark A. van de Wiel , Wessel N. van Wieringen

Clustering is a crucial task in various domains of knowledge, including medicine, epidemiology, genomics, environmental science, economics, and visual sciences, among others. Methodologies for inferring the number of clusters have often…

统计方法学 · 统计学 2025-05-26 Clara Grazian

In Cowell et al. (2007), a Bayesian network for analysis of mixed traces of DNA was presented using gamma distributions for modelling peak sizes in the electropherogram. It was demonstrated that the analysis was sensitive to the choice of a…

统计方法学 · 统计学 2013-06-21 Therese Graversen , Steffen Lauritzen

Prediction with the possibility of abstention (or selective prediction) is an important problem for error-critical machine learning applications. While well-studied in the classification setup, selective approaches to regression are much…

机器学习 · 统计学 2023-09-29 Fedor Noskov , Alexander Fishkov , Maxim Panov

Many real world problems exhibit patterns that have periodic behavior. For example, in astrophysics, periodic variable stars play a pivotal role in understanding our universe. An important step when analyzing data from such processes is the…

机器学习 · 计算机科学 2012-08-20 Yuyang Wang , Roni Khardon , Pavlos Protopapas

In ecology we may find scenarios where the same phenomenon (species occurrence, species abundance, etc.) is observed using two different types of samplers. For instance, species data can be collected from scientific sampling with a…

Like mean, quantile and variance, mode is also an important measure of central tendency and data summary. Many practical questions often focus on "Which element (gene or file or signal) occurs most often or is the most typical among all…

统计方法学 · 统计学 2012-08-03 Keming Yu , Katerina Aristodemou

In this paper we propose a new methodology for solving a discrete time stochastic Markovian control problem under model uncertainty. By utilizing the Dirichlet process, we model the unknown distribution of the underlying stochastic process…

最优化与控制 · 数学 2022-03-29 Tao Chen , Jiyoun Myung

When modeling a probability distribution with a Bayesian network, we are faced with the problem of how to handle continuous variables. Most previous work has either solved the problem by discretizing, or assumed that the data are generated…

机器学习 · 计算机科学 2013-02-21 George H. John , Pat Langley

Estimation of genewise variance arises from two important applications in microarray data analysis: selecting significantly differentially expressed genes and validation tests for normalization of microarray data. We approach the problem by…

统计理论 · 数学 2010-11-11 Jianqing Fan , Yang Feng , Yue S. Niu

We present a method that models the evolution of an unbounded number of time series clusters by switching among an unknown number of regimes with linear dynamics. We develop a Bayesian non-parametric approach using a hierarchical Dirichlet…

机器学习 · 统计学 2025-10-09 Adrián Pérez-Herrero , Paulo Félix , Jesús Presedo , Carl Henrik Ek

Test-time scaling can improve model performance by aggregating stochastic reasoning trajectories. However, achieving sample-efficient test-time self-consistency under a limited budget remains an open challenge. We introduce PETS (Principled…

机器学习 · 计算机科学 2026-02-20 Zhangyi Liu , Huaizhi Qu , Xiaowei Yin , He Sun , Yanjun Han , Tianlong Chen , Zhun Deng

We introduce a scalable Bayesian preference learning method for identifying convincing arguments in the absence of gold-standard rat- ings or rankings. In contrast to previous work, we avoid the need for separate methods to perform quality…

计算与语言 · 计算机科学 2018-06-08 Edwin Simpson , Iryna Gurevych

It is well known that opportunistic scheduling algorithms are throughput optimal under dynamic channel and network conditions. However, these algorithms achieve a hypothetical rate region which does not take into account the overhead…

网络与互联网体系结构 · 计算机科学 2019-11-12 Mehmet Karaca , Tansu Alpcan , Ozgur Ercetin

As modern neural networks get more complex, specifying a model with high predictive performance and sound uncertainty quantification becomes a more challenging task. Despite some promising theoretical results on the true posterior…

机器学习 · 计算机科学 2025-06-18 Alisa Sheinkman , Sara Wade

This paper is concerned with the numerical solution of model-based, Bayesian inverse problems. We are particularly interested in cases where the cost of each likelihood evaluation (forward-model call) is expensive and the number of un-…

统计计算 · 统计学 2016-07-25 Isabell M. Franck , P. S. Koutsourelakis
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