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Randomized experiments have been the gold standard for assessing the effectiveness of a treatment or policy. The classical complete randomization approach assigns treatments based on a prespecified probability and may lead to inefficient…

统计方法学 · 统计学 2023-10-26 Waverly Wei , Xinwei Ma , Jingshen Wang

Count outcomes in longitudinal studies are frequent in clinical and engineering studies. In frequentist and Bayesian statistical analysis, methods such as Mixed linear models allow the variability or correlation within individuals to be…

统计方法学 · 统计学 2024-07-15 Alejandra Estefanía Patiño Hoyos , Johnatan Cardona Jiménez

Motivated by modern applications such as computerized adaptive testing, sequential rank aggregation, and heterogeneous data source selection, we study the problem of active sequential estimation, which involves adaptively selecting…

统计理论 · 数学 2024-02-14 Xiaoou Li , Hongru Zhao

Individualized treatment rules aim to identify if, when, which, and to whom treatment should be applied. A globally aging population, rising healthcare costs, and increased access to patient-level data have created an urgent need for…

统计方法学 · 统计学 2019-01-04 Ying-Qi Zhao , Eric B. Laber , Yang Ning , Sumona Saha , Bruce Sands

The risk of financial positions is measured by the minimum amount of capital to raise and invest in eligible portfolios of traded assets in order to meet a prescribed acceptability constraint. We investigate nondegeneracy, finiteness and…

风险管理 · 定量金融 2014-03-05 Walter Farkas , Pablo Koch-Medina , Cosimo Munari

In binary classification applications, conservative decision-making that allows for abstention can be advantageous. To this end, we introduce a novel approach that determines the optimal cutoff interval for risk scores, which can be…

机器学习 · 统计学 2025-10-01 Yishu Wei , Wen-Yee Lee , George Ekow Quaye , Xiaogang Su

The efficacy of an intervention can be assessed by randomizing patients to different diagnostic tests instead of directly to an intervention and control. This principle is applied by allocating individuals to intervention if the test result…

应用统计 · 统计学 2022-01-11 Huw Llewelyn

LLMs are increasingly used to make or support high-stakes decisions under uncertainty, where alignment depends not only on factual accuracy but on how models weigh tradeoffs between different outcomes. We present an empirical pipeline for…

机器学习 · 计算机科学 2026-05-12 Khurram Yamin , Jingjing Tang , Eric Horvitz , Bryan Wilder

This paper presents a weighted optimization framework that unifies the binary,multi-valued, continuous, as well as mixture of discrete and continuous treatment, under the unconfounded treatment assignment. With a general loss function, the…

计量经济学 · 经济学 2018-08-20 Chunrong Ai , Oliver Linton , Kaiji Motegi , Zheng Zhang

Stratifying factors, like age and gender, can modify the effect of treatments and exposures on risk of a studied outcome. Several effect measures, including the relative risk, hazard ratio, odds ratio, and risk difference, can be used to…

统计方法学 · 统计学 2021-11-05 Jake Shannin , Babette A. Brumback

A research frontier has emerged in scientific computation, wherein numerical error is regarded as a source of epistemic uncertainty that can be modelled. This raises several statistical challenges, including the design of statistical…

Understanding cancer cell differentiation is essential for advancing its detection, diagnosis, and treatment. Mathematical models significantly contribute to this by providing a theoretical framework to understand the complex interactions…

组织与器官 · 定量生物学 2025-08-18 Marcela V. Reale , Gustavo Paccosi , David H. Margarit , Lilia Romanelli

No unmeasured confounding is often assumed in estimating treatment effects in observational data when using approaches such as propensity scores and inverse probability weighting. However, in many such studies due to the limitation of the…

应用统计 · 统计学 2019-08-06 Rong Huang , Ronghui Xu , Parambir S. Dulai

We propose a novel method for estimating nonseparable selection models. We show that, for a given selection function, the potential outcome distributions are nonparametrically identified from the selected outcome distributions and can be…

计量经济学 · 经济学 2026-05-05 Fan Wu , Yi Xin

We investigate the probabilistic feasibility of randomized solutions to two distinct classes of uncertain multi-agent optimization programs. We first assume that only the constraints of the program are affected by uncertainty, while the…

最优化与控制 · 数学 2020-09-29 George Pantazis , Filiberto Fele , Kostas Margellos

A key output of network meta-analysis (NMA) is the relative ranking of treatments; nevertheless, it has attracted substantial criticism. Existing ranking methods often lack clear interpretability and fail to adequately account for…

Clinical decisions are often guided by clinical prediction models or diagnostic tests. Decision curve analysis (DCA) combines classical assessment of predictive performance with the consequences of using these strategies for clinical…

统计方法学 · 统计学 2023-08-07 Giuliano N. F. Cruz , Keegan Korthauer

Empirical welfare analyses often impose stringent parametric assumptions on individuals' preferences and neglect unobserved preference heterogeneity. We develop a framework to conduct individual and social welfare analysis for discrete…

理论经济学 · 经济学 2025-05-20 Bart Capéau , Liebrecht De Sadeleer , Sebastiaan Maes

Probabilistic control design is founded on the principle that a rational agent attempts to match modelled with an arbitrary desired closed-loop system trajectory density. The framework was originally proposed as a tractable alternative to…

机器学习 · 计算机科学 2023-11-16 Tom Lefebvre

There is a growing body of work on sorting and selection in models other than the unit-cost comparison model. This work is the first treatment of a natural stochastic variant of the problem where the cost of comparing two elements is a…

数据结构与算法 · 计算机科学 2007-10-02 Stanislav Angelov , Keshav Kunal , Andrew McGregor
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