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Personalized predictive medicine necessitates the modeling of patient illness and care processes, which inherently have long-term temporal dependencies. Healthcare observations, recorded in electronic medical records, are episodic and…

机器学习 · 统计学 2017-04-12 Trang Pham , Truyen Tran , Dinh Phung , Svetha Venkatesh

The wide-spread adoption of representation learning technologies in clinical decision making strongly emphasizes the need for characterizing model reliability and enabling rigorous introspection of model behavior. While the former need is…

机器学习 · 计算机科学 2020-05-01 Jayaraman J. Thiagarajan , Prasanna Sattigeri , Deepta Rajan , Bindya Venkatesh

Deep learning models for clinical event prediction on electronic health records (EHR) often suffer performance degradation when deployed under different data distributions. While domain adaptation (DA) methods can mitigate such shifts, its…

机器学习 · 计算机科学 2026-02-16 Pengfei Hu , Chang Lu , Feifan Liu , Yue Ning

The increasing availability of large collections of electronic health record (EHR) data and unprecedented technical advances in deep learning (DL) have sparked a surge of research interest in developing DL based clinical decision support…

机器学习 · 计算机科学 2021-12-07 Di Jin , Elena Sergeeva , Wei-Hung Weng , Geeticka Chauhan , Peter Szolovits

In recent years, deep learning models have been extensively applied to biological data across various modalities. Discriminative deep learning models have excelled at classifying images into categories (e.g., healthy versus diseased,…

计算机视觉与模式识别 · 计算机科学 2025-02-17 Anis Bourou , Saranga Kingkor Mahanta , Thomas Boyer , Valérie Mezger , Auguste Genovesio

Foundation models in healthcare have largely adopted self supervised pretraining objectives inherited from natural language processing and computer vision, emphasizing reconstruction and large scale representation learning prior to…

机器学习 · 计算机科学 2026-03-24 Yang Zhang , Li Fan , Samuel Lawrence , Shi Li

Quantification of anatomical shape changes currently relies on scalar global indexes which are largely insensitive to regional or asymmetric modifications. Accurate assessment of pathology-driven anatomical remodeling is a crucial step for…

In countries that enabled patients to choose their own providers, a common problem is that the patients did not make rational decisions, and hence, fail to use healthcare resources efficiently. This might cause problems such as overwhelming…

计算机与社会 · 计算机科学 2020-06-25 Lichin Chen , Yu Tsao , Ji-Tian Sheu

In 2019, The Centers for Medicare and Medicaid Services (CMS) launched an Artificial Intelligence (AI) Health Outcomes Challenge seeking solutions to predict risk in value-based care for incorporation into CMS Innovation Center payment and…

机器学习 · 计算机科学 2021-05-21 Chuhong Lahlou , Ancil Crayton , Caroline Trier , Evan Willett

Machine learning enables extracting clinical insights from large temporal datasets. The applications of such machine learning models include identifying disease patterns and predicting patient outcomes. However, limited interpretability…

机器学习 · 计算机科学 2023-11-30 Yu Chen , Nivedita Bijlani , Samaneh Kouchaki , Payam Barnaghi

Cardiovascular disease (CVD) risk prediction models are essential for identifying high-risk individuals and guiding preventive actions. However, existing models struggle with the challenges of real-world clinical practice as they…

While pioneering deep learning methods have made great strides in analyzing electronic health record (EHR) data, they often struggle to fully capture the semantics of diverse medical codes from limited data. The integration of external…

机器学习 · 计算机科学 2024-08-26 Zhihao Yu , Yujie Jin , Yongxin Xu , Xu Chu , Yasha Wang , Junfeng Zhao

Causal inference and model interpretability research are gaining increasing attention, especially in the domains of healthcare and bioinformatics. Despite recent successes in this field, decorrelating features under nonlinear environments…

机器学习 · 计算机科学 2022-09-30 Junda Wang , Weijian Li , Han Wang , Hanjia Lyu , Caroline Thirukumaran , Addisu Mesfin , Jiebo Luo

Clinical decisions are high-stakes and require explicit justification, making model interpretability essential for auditing deep clinical models prior to deployment. As the ecosystem of model architectures and explainability methods…

机器学习 · 计算机科学 2026-03-27 Yongda Fan , John Wu , Andrea Fitzpatrick , Naveen Baskaran , Jimeng Sun , Adam Cross

Despite the outstanding performance of deep learning models in clinical prediction tasks, explainability remains a significant challenge. Inspired by transformer architectures, we introduce the Temporal-Feature Cross Attention Mechanism…

机器学习 · 计算机科学 2025-09-22 Yubo Li , Xinyu Yao , Rema Padman

Accurate and explainable health event predictions are becoming crucial for healthcare providers to develop care plans for patients. The availability of electronic health records (EHR) has enabled machine learning advances in providing these…

机器学习 · 计算机科学 2021-05-18 Chang Lu , Chandan K. Reddy , Prithwish Chakraborty , Samantha Kleinberg , Yue Ning

Clinical outcome prediction based on the Electronic Health Record (EHR) plays a crucial role in improving the quality of healthcare. Conventional deep sequential models fail to capture the rich temporal patterns encoded in the longand…

机器学习 · 计算机科学 2019-08-27 Luchen Liu , Haoran Li , Zhiting Hu , Haoran Shi , Zichang Wang , Jian Tang , Ming Zhang

We have three contributions in this work: 1. We explore the utility of a stacked denoising autoencoder and a paragraph vector model to learn task-independent dense patient representations directly from clinical notes. To analyze if these…

计算与语言 · 计算机科学 2018-07-05 Madhumita Sushil , Simon Šuster , Kim Luyckx , Walter Daelemans

This study proposes a Transformer-based longitudinal modeling method to address challenges in clinical risk classification with heterogeneous Electronic Health Record (EHR) data, including irregular temporal patterns, large modality…

机器学习 · 计算机科学 2025-11-07 Anzhuo Xie , Wei-Chen Chang

Deep Learning based models are currently dominating most state-of-the-art solutions for disease prediction. Existing works employ RNNs along with multiple levels of attention mechanisms to provide interpretability. These deep learning…

机器学习 · 统计学 2022-06-01 Subhadip Maji , Raghav Bali , Sree Harsha Ankem , Kishore V Ayyadevara
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