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Brillouin microscopy is an emerging optical elastography technique that can be used to assess mechanical properties of biological samples in a 3D, all-optical and hence non-contact fashion. However, the low cross-section of spontaneous…

光学 · 物理学 2024-09-04 Carlo Bevilacqua , Robert Prevedel

The role and importance of mechanical properties of cells and tissues in cellular function, development as well as disease has widely been acknowledged, however standard techniques currently used to assess them exhibit intrinsic…

生物物理 · 物理学 2019-01-09 Robert Prevedel , Alba Diz-Muñoz , Giancarlo Ruocco , Giuseppe Antonacci

Brillouin spectroscopy and imaging are emerging techniques in analytical science, biophotonics and biomedicine. They are based on Brillouin light scattering from acoustic waves or phonons in the GHz range, providing a nondestructive…

生物物理 · 物理学 2021-10-12 Francesca Palombo , Daniele Fioretto

Many problems in mechanobiology urgently require characterisation of the micromechanical properties of the fibrous proteins of cells and tissues. Brillouin light scattering has been proposed as a new optical elastography technique to meet…

Frequency- and time-domain Brillouin scattering spectroscopy are powerful tools to read out the mechanical properties of complex systems in material and life sciences. Indeed, coherent acoustic phonons in the time-domain method offer…

光学 · 物理学 2023-01-06 Ayumu Ishijima , Shinga Okabe , Ichiro Sakuma , Keiichi Nakagawa

Brillouin spectroscopy is a century-old technique that has recently received renewed interest, as modern instrumentation has transformed it into a powerful contactless and label-free probe of micromechanical properties for biomedical…

Brillouin microscopy is an emerging optical technique for probing mechanical properties with submicron resolution, offering fully non-contact, label-free operation. Despite its unique capabilities, broader adoption has been limited by slow…

光学 · 物理学 2026-04-22 Mikolaj Pochylski

Optical imaging with mechanical contrast is critical for material and biological discovery since it allows contactless light-radiation force-excitation within the sample, as opposed to traditional mechanical imaging. Whilst optical…

Time-domain Brillouin scattering is an all-optical experimental technique based on ultrafast lasers applied for generation and detection of coherent acoustic pulses on time durations of picoseconds and length scales of nanometers. In…

应用物理 · 物理学 2018-06-12 Vitalyi E. Gusev , Pascal Ruello

Brillouin microscopy is rapidly emerging as a powerful technique for imaging the mechanical properties of biological specimens in a label-free, non-contact manner. We present a standardized file format and open-source tools to facilitate…

There is currently a renewed interest in the development of experimental methods to achieve the elastic characterization of thin films, multilayers and acoustic resonators operating in the GHz range of frequencies. The potentialities of…

应用物理 · 物理学 2019-08-30 Giovanni Carlotti

Brillouin imaging is increasingly recognized to be a powerful technique that enables non-invasive measurement of the mechanical properties of cells and tissues on a microscopic scale. This provides an unprecedented tool for investigating…

生物物理 · 物理学 2020-01-22 Christine Poon , Joshua Chou , Michael Cortie , Irina Kabakova

Brillouin Light Scattering is a powerful technique to measure the microwave excitations present in a magnetic system. In microfocused mode, the light is focused on the sample using a microscope objective. This accelerates substantially the…

介观与纳米尺度物理 · 物理学 2025-06-30 Nessrine Benaziz , Thibaut Devolder , Jean-Paul Adam

Brillouin microscopy is an emerging technique for all-optical biomechanical imaging without the need for physical contact with the sample or for an external mechanical stimulus. However, Brillouin microscopy often retrieves a single,…

光学 · 物理学 2024-02-27 Roni Shaashoua , Tal Levy , Barak Rotblat , Alberto Bilenca

Time-domain Brillouin scattering is an opto-acousto-optical probe technique for the evaluation of the transparent materials. Ultrashort pump laser pulses via optoacoustic conversion launch in the sample picosecond coherent acoustic pulses.…

应用物理 · 物理学 2020-06-15 Vitalyi E. Gusev

Spontaneous Brillouin scattering (SpBS) provides a non-contact tool for probing the mechanical and thermodynamic properties of materials, enabling important applications such as distributed optical fiber sensing and high-resolution…

Mounting evidence connects the biomechanical properties of tissues to the development of eye diseases such as keratoconus, a common disease in which the cornea thins and bulges into a conical shape. However, measuring biomechanical changes…

Brillouin light scattering spectroscopy is a powerful technique which incorporates several extensions such as space-, time-, phase- and wave-vector resolution. Here, we report on the improvement of the wave-vector resolution by including an…

其他凝聚态物理 · 物理学 2010-04-20 T. Neumann , T. Schneider , A. A. Serga , B. Hillebrands

The spatial resolution of direct-modulation Brillouin optical correlation-domain reflectometry is studied with respect to modulation amplitude and frequency. Results suggest that optimal resolution improvement is achieved by increasing…

仪器与探测器 · 物理学 2023-05-09 Seiga Ochi , Kouta Ozaki , Kohei Noda , Heeyoung Lee , Kentaro Nakamura , Yosuke Mizuno
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