相关论文: Projected $t$-SNE for batch correction

We introduce a nonlinear method for directly embedding large, sparse, stochastic graphs into low-dimensional spaces, without requiring vertex features to reside in, or be transformed into, a metric space. Graph data and models are prevalent…

The clustering and visualisation of high-dimensional data is a ubiquitous task in modern data science. Popular techniques include nonlinear dimensionality reduction methods like t-SNE or UMAP. These methods face the `scale-problem' of…

Causal inference plays an important role in under standing the underlying mechanisation of the data generation process across various domains. It is challenging to estimate the average causal effect and individual causal effects from…

This paper presents a kernelized version of the t-SNE algorithm, capable of mapping high-dimensional data to a low-dimensional space while preserving the pairwise distances between the data points in a non-Euclidean metric. This can be…

The central problem in biomedical imaging are batch effects: systematic technical variations unrelated to the biological signal of interest. These batch effects critically undermine experimental reproducibility and are the primary cause of…

We extend a well-known dimension reduction method, t-distributed stochastic neighbor embedding (t-SNE), from non-parametric to parametric by training neural networks. The main advantage of a parametric technique is the generalization of…

Motivation: As cancer researchers have come to appreciate the importance of intratumor heterogeneity, much attention has focused on the challenges of accurately profiling heterogeneity in individual patients. Experimental technologies for…

We describe a new method called t-ETE for finding a low-dimensional embedding of a set of objects in Euclidean space. We formulate the embedding problem as a joint ranking problem over a set of triplets, where each triplet captures the…

Dimensionality reduction methods, also known as projections, are frequently used for exploring multidimensional data in machine learning, data science, and information visualization. Among these, t-SNE and its variants have become very…

Large-scale numerical simulations often produce high-dimensional gridded data that is challenging to process for downstream applications. A prime example is numerical weather prediction, where atmospheric processes are modeled using…

Sensor data analysis plays a key role in health assessment of critical equipment. Such data are multivariate and exhibit nonlinear relationships. This paper describes how one can exploit nonlinear dimension reduction techniques, such as the…

Non-linear dimensionality reduction (NLDR) methods such as t-distributed stochastic neighbour embedding (t-SNE) are ubiquitous in the natural sciences, however, the appropriate use of these methods is difficult because of their complex…

The dimensionality reduction has been widely introduced to use the high-dimensional data for regression, classification, feature analysis, and visualization. As the one technique of dimensionality reduction, a stochastic neighbor embedding…

Batch Normalization (BN) and its variants have delivered tremendous success in combating the covariate shift induced by the training step of deep learning methods. While these techniques normalize feature distributions by standardizing with…

Progressive Visual Analytics aims at improving the interactivity in existing analytics techniques by means of visualization as well as interaction with intermediate results. One key method for data analysis is dimensionality reduction, for…

Neural likelihood estimation methods for simulation-based inference can suffer from performance degradation when the modeled data is very high-dimensional or lies along a lower-dimensional manifold, which is due to the inability of the…

In this paper, we develop a multiply robust inference procedure of the average treatment effect (ATE) for data with high-dimensional covariates. We consider the case where it is difficult to correctly specify a single parametric model for…

With the recent surge in big data analytics for hyper-dimensional data there is a renewed interest in dimensionality reduction techniques for machine learning applications. In order for these methods to improve performance gains and…

Single-cell RNA sequencing (scRNA-seq) has revolutionized our ability to analyze gene expression at the cellular level. By providing data on gene expression for each individual cell, scRNA-seq generates large datasets with thousands of…

We propose a novel method, scTree, for single-cell Tree Variational Autoencoders, extending a hierarchical clustering approach to single-cell RNA sequencing data. scTree corrects for batch effects while simultaneously learning a…