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Cell counting in biomedical imaging is pivotal for various clinical applications, yet the interpretability of deep learning models in this domain remains a significant challenge. We propose a novel prototype-based method for interpretable…

计算机视觉与模式识别 · 计算机科学 2025-11-26 Abdurahman Ali Mohammed , Wallapak Tavanapong , Catherine Fonder , Donald S. Sakaguchi

Kernel dimensionality reduction (KDR) algorithms find a low dimensional representation of the original data by optimizing kernel dependency measures that are capable of capturing nonlinear relationships. The standard strategy is to first…

机器学习 · 统计学 2019-09-26 Chieh Wu , Jared Miller , Yale Chang , Mario Sznaier , Jennifer Dy

We propose a novel perspective to understand deep neural networks in an interpretable disentanglement form. For each semantic class, we extract a class-specific functional subnetwork from the original full model, with compressed structure…

机器学习 · 计算机科学 2019-10-08 Yulong Wang , Xiaolin Hu , Hang Su

Interpretability can be critical for the safe and responsible use of machine learning models in high-stakes applications. So far, evolutionary computation (EC), in particular in the form of genetic programming (GP), represents a key enabler…

神经与进化计算 · 计算机科学 2022-04-06 Marco Virgolin , Eric Medvet , Tanja Alderliesten , Peter A. N. Bosman

Deep learning has driven significant advances in medical image analysis, yet its adoption in clinical practice remains constrained by the large size and lack of transparency in modern models. Advances in interpretability techniques such as…

计算机视觉与模式识别 · 计算机科学 2025-09-23 Nikita Malik , Pratinav Seth , Neeraj Kumar Singh , Chintan Chitroda , Vinay Kumar Sankarapu

Interpretable entity representations (IERs) are sparse embeddings that are "human-readable" in that dimensions correspond to fine-grained entity types and values are predicted probabilities that a given entity is of the corresponding type.…

计算与语言 · 计算机科学 2022-12-06 Diego Garcia-Olano , Yasumasa Onoe , Joydeep Ghosh , Byron C. Wallace

For machine learning models to be most useful in numerous sociotechnical systems, many have argued that they must be human-interpretable. However, despite increasing interest in interpretability, there remains no firm consensus on how to…

机器学习 · 计算机科学 2021-02-03 Andrew Slavin Ross , Nina Chen , Elisa Zhao Hang , Elena L. Glassman , Finale Doshi-Velez

This paper presents Prototypical Contrastive Learning (PCL), an unsupervised representation learning method that addresses the fundamental limitations of instance-wise contrastive learning. PCL not only learns low-level features for the…

计算机视觉与模式识别 · 计算机科学 2021-03-31 Junnan Li , Pan Zhou , Caiming Xiong , Steven C. H. Hoi

Time series forecasting enables early warning and has driven asset performance management from traditional planned maintenance to predictive maintenance. However, the lack of interpretability in forecasting methods undermines users' trust…

机器学习 · 计算机科学 2026-03-04 Bo Liu , Shao-Bo Lin , Changmiao Wang , Xiaotong Liu

Machine-learning models have demonstrated great success in learning complex patterns that enable them to make predictions about unobserved data. In addition to using models for prediction, the ability to interpret what a model has learned…

机器学习 · 统计学 2019-11-15 W. James Murdoch , Chandan Singh , Karl Kumbier , Reza Abbasi-Asl , Bin Yu

To learn about real world phenomena, scientists have traditionally used models with clearly interpretable elements. However, modern machine learning (ML) models, while powerful predictors, lack this direct elementwise interpretability (e.g.…

机器学习 · 统计学 2024-07-16 Timo Freiesleben , Gunnar König , Christoph Molnar , Alvaro Tejero-Cantero

In complex visual recognition tasks it is typical to adopt multiple descriptors, that describe different aspects of the images, for obtaining an improved recognition performance. Descriptors that have diverse forms can be fused into a…

计算机视觉与模式识别 · 计算机科学 2015-06-15 Jayaraman J. Thiagarajan , Karthikeyan Natesan Ramamurthy , Andreas Spanias

With the advent of kernel methods, automating the task of specifying a suitable kernel has become increasingly important. In this context, the Multiple Kernel Learning (MKL) problem of finding a combination of pre-specified base kernels…

机器学习 · 计算机科学 2012-07-03 Abhishek Kumar , Alexandru Niculescu-Mizil , Koray Kavukcuoglu , Hal Daume

Deep neural networks that yield human interpretable decisions by architectural design have lately become an increasingly popular alternative to post hoc interpretation of traditional black-box models. Among these networks, the arguably most…

计算机视觉与模式识别 · 计算机科学 2021-06-24 Adrian Hoffmann , Claudio Fanconi , Rahul Rade , Jonas Kohler

Application of interpretable machine learning techniques on medical datasets facilitate early and fast diagnoses, along with getting deeper insight into the data. Furthermore, the transparency of these models increase trust among…

机器学习 · 计算机科学 2025-06-05 Sreejita Ghosh , Elizabeth S. Baranowski , Michael Biehl , Wiebke Arlt , Peter Tino , Kerstin Bunte

Machine learning is capable of discriminating phases of matter, and finding associated phase transitions, directly from large data sets of raw state configurations. In the context of condensed matter physics, most progress in the field of…

统计力学 · 物理学 2017-12-06 Pedro Ponte , Roger G. Melko

Prototype-based neural networks offer interpretable predictions by comparing inputs to learned, representative signal patterns anchored in training data. While such models have shown promise in the classification of physiological data, it…

机器学习 · 计算机科学 2026-05-28 Sahil Sethi , David Chen , Michael C. Burkhart , Nipun Bhandari , Bashar Ramadan , Brett Beaulieu-Jones

Machine learning models can represent climate processes that are nonlocal in horizontal space, height, and time, often by combining information across these dimensions in highly nonlinear ways. While this can improve predictive skill, it…

机器学习 · 计算机科学 2026-05-14 Savannah L. Ferretti , Jerry Lin , Sara Shamekh , Jane W. Baldwin , Michael S. Pritchard , Tom Beucler

Kernel methods have been proven to be a powerful tool for the integration and analysis of highthroughput technologies generated data. Kernels offer a nonlinear version of any linear algorithm solely based on dot products. The kernelized…

应用统计 · 统计学 2024-11-27 Mitja Briscik , Marie-Agnès Dillies , Sébastien Déjean

Molecular property prediction constitutes a cornerstone of drug discovery and materials science, necessitating models capable of disentangling complex structure-property relationships across diverse molecular modalities. Existing approaches…

机器学习 · 计算机科学 2026-03-24 Long Xu , Junping Guo , Jianbo Zhao , Jianbo Lu , Yuzhong Peng