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Purpose: This study aims to optimize and characterize the response of a mPSD for in vivo dosimetry in HDR brachytherapy. Methods: An exhaustive analysis was carried out in order to obtain an optimized mPSD design that maximize the…

Purpose: We sought to evaluate the feasibility of using machine learning algorithms for multipoint plastic scintillator detector calibration in high-dose-rate brachytherapy. Methods: The dosimetry system consisted of an optimized 1-mm-core…

Since large dose are administrated to the patient in brachytherapy treatment, ensuring the right dose is delivered is highly critical. This study presents a first step in solving the standing issue of accurately knowing the dosimeter…

医学物理 · 物理学 2018-12-27 Daline Tho , Luc Beaulieu

Purpose: We introduce a novel concept of a compact multiprobe scintillator detector and demonstrate its applicability in HDR-brachytherapy. Our fabricated seven-probe system is sufficiently narrow to be inserted in a brachytherapy needle or…

The high dose gradients near the source characteristics of brachytherapy are equivalent to nefarious effects if unnoticed errors take place during the patient treatment. In vivo dosimetry is the only method to quantify the delivered dose.…

Purpose: HDR brachytherapy is a widely adopted modality for cancer treatment. However, it is not free from error and uncertainty. In-vivo dosimetry (IVD) is the only technique that can confirm correct dose delivery. This study details and…

医学物理 · 物理学 2025-12-10 Chahrazed Ghannoudi , Marie-Claude Lavallee , Benjamin Cote , Luc Beaulieu

Plastic scintillation detectors are increasingly used to measure dose distributions in the context of radiotherapy treatments. Their water-equivalence, real-time response and high spatial resolution distinguish them from traditional…

医学物理 · 物理学 2021-09-22 Emily Cloutier , Louis Archambault , Luc Beaulieu

This study introduces the HYPERSCINT research platform, the first commercially available scintillation dosimetry platform capable of multi-point dosimetry through the hyperspectral approach. Optic and dosimetric performances of the system…

仪器与探测器 · 物理学 2021-04-19 Emilie Jean , Francois Therriault-Proulx , Luc Beaulieu

Introduction: Real-time dosimetry of surface doses in electron beams has not been widely established yet. Plastic scintillation detectors (PSD) promise high spatial resolution and real-time dosimetry with minimum perturbation of the…

This study aims to introduce IViST (In Vivo Source Tracking), a novel multi-sensors dosimetry platform for real-time treatment monitoring in HDR brachytherapy. IViST is a platform that comprises 3 parts: 1) an optimized and characterized…

医学物理 · 物理学 2020-06-16 Haydee M. Linares Rosales , Audrey Cantin , Sylviane Aubin , Sam Beddar , Luc Beaulieu

Purpose: For more than a decade that plastic optical fiber based dosimeters have been developed for medical applications. The feasibility of dosimeters using optical fibers that are almost Cherenkov light free has been demonstrated in some…

医学物理 · 物理学 2011-09-30 Florbela Rêgo , Luis Peralta , Maria da Conceição Abreu

Background: Scintillation dosimetry has promising qualities for ultra-high dose rate (UHDR) radiotherapy (RT), but no system has shown compatibility with mean dose rates ($\bar{DR}$) above 100 Gy/s and doses per pulse ($D_p$) exceeding 1.5…

医学物理 · 物理学 2024-03-06 Alexander Baikalov , Daline Tho , Kevin Liu , Stefan Bartzsch , Sam Beddar , Emil Schüler

FLASH-RT has proven beneficial in preclinical studies. However, the lack of accurate real time 2D dosimetry is a limiting factor. In this work, an innovative solution for 2D real time dosimetry in UHDR electron beams is presented. The…

The increasing interest in FLASH-RT has lead to the conversion of linear accelerators to enable ultra-high dose rate (UHDR) beams for preclinical research. Dosimetry hereof remains challenging with several crucial aspects missing. This work…

Anatomical motion and deformation pose challenges to the understanding of the delivered dose distribution during radiotherapy treatments. Hence, deformable image registration (DIR) algorithms are increasingly used to map contours and dose…

医学物理 · 物理学 2021-09-22 Emily Cloutier , Luc Beaulieu , Louis Archambault

Background: Ultra-high dose rate proton therapy shows promise in tissue sparing by enhancing therapeutic ratio through the FLASH effect. In radiotherapy, accurate in vivo dosimetry is crucial for quality assurance, but remains challenging…

{\bf Purpose:} This study evaluates a compact biocompatible Seven-probe Scintillator Detector (7SD) for monitoring HDR-BT treatment sequences across a range of dwell times and source-probe spacings representative of most HDR-BT techniques.…

Plastic scintillators detectors (PSDs) have been studied as dosimeters, since they provide a cost-effective alternative to conventional ionization chambers. Measurement and analysis of energy dependency were performed on a Siemens Mammomat…

仪器与探测器 · 物理学 2017-11-06 J. Antunes , J. Machado , L. Peralta , N. Matela

Ultra-high dose rate electron sources require dose rate independent dosimeters and a calibrated dose control system for accurate delivery. In this study, we developed a single-pulse dose monitoring and a real-time dose-based control system…

FLASH Radiotherapy (RT) is a potentially new cancer radiotherapy technique where an entire therapeutic dose is delivered in about 0.1 s and at ~1000 times higher dose rate than in conventional RT. For clinical trials to be conducted safely,…

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