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Parkinson's disease (PD) is a common and complex neurodegenerative disorder with 5 stages in the Hoehn and Yahr scaling. Given the heterogeneity of PD, it is challenging to classify early stages 1 and 2 and detect brain function…

神经元与认知 · 定量生物学 2022-07-22 Xueqi Guo , Sule Tinaz , Nicha C. Dvornek

Alzheimer's disease (AD) and sleep disorders exhibit a close association, where disruptions in sleep patterns often precede the onset of Mild Cognitive Impairment (MCI) and early-stage AD. This study delves into the potential of utilizing…

Pathological slowing in the electroencephalogram (EEG) is widely investigated for the diagnosis of neurological disorders. Currently, the gold standard for slowing detection is the visual inspection of the EEG by experts, which is…

This study investigates the detection and classification of depressive and non-depressive states using deep learning approaches. Depression is a prevalent mental health disorder that substantially affects quality of life, and early…

定量方法 · 定量生物学 2026-01-19 Mohammad Reza Yousefi , Hajar Ismail Al-Tamimi , Amin Dehghani

Parkinson's disease (PD) is a prevalent neurodegenerative disorder known for its impact on motor neurons, causing symptoms like tremors, stiffness, and gait difficulties. This study explores the potential of vocal feature alterations in PD…

Study Objective: Sleep is reflected not only in the electroencephalogram but also in heart rhythms and breathing patterns. Therefore, we hypothesize that it is possible to accurately stage sleep based on the electrocardiogram (ECG) and…

Diabetic retinopathy (DR) is the primary cause of vision loss among grownup people around the world. In four out of five cases having diabetes for a prolonged period leads to DR. If detected early, more than 90 percent of the new DR…

计算机视觉与模式识别 · 计算机科学 2020-06-16 Niloy Sikder , Md. Sanaullah Chowdhury , Abu Shamim Mohammad Arif , Abdullah-Al Nahid

Diabetic Retinopathy (DR) is a severe complication that may lead to retinal vascular damage and is one of the leading causes of vision impairment and blindness. DR broadly is classified into two stages - non-proliferative (NPDR), where…

图像与视频处理 · 电气工程与系统科学 2021-06-04 Aditya Jyoti Paul

The ability to accurately detect onset of dementia is important in the treatment of the disease. Clinically, the diagnosis of Alzheimer Disease (AD) and Mild Cognitive Impairment (MCI) patients are based on an integrated assessment of…

信号处理 · 电气工程与系统科学 2022-11-18 Wan-Ting Hsieh , Jeremy Lefort-Besnard , Hao-Chun Yang , Li-Wei Kuo , Chi-Chun Lee

- Background / Introduction: Driver drowsiness is a significant concern and one of the leading causes of traffic accidents. Advances in cognitive neuroscience and computer science have enabled the detection of drivers' drowsiness using…

Parkinson's disease (PD) is a debilitating neurodegenerative disease that has severe impacts on an individual's quality of life. Compared with structural and functional MRI-based biomarkers for the disease, electroencephalography (EEG) can…

机器学习 · 计算机科学 2024-08-05 Christopher Neves , Yong Zeng , Yiming Xiao

There is a pressing need to automatically understand the state and progression of chronic neurological diseases such as dementia. The emergence of state-of-the-art sensing platforms offers unprecedented opportunities for indirect and…

Accurate early diagnosis and monitoring of neurodegenerative conditions is essential for effective disease management and delivery of medication and treatment. This research develops automatic methods for detecting brain imaging preclinical…

神经与进化计算 · 计算机科学 2019-10-15 Amir Dehsarvi , Stephen L. Smith

We evaluate the effectiveness of combining brain connectivity metrics with signal statistics for early stage Parkinson's Disease (PD) classification using electroencephalogram data (EEG). The data is from 5 arousal states - wakeful and four…

神经元与认知 · 定量生物学 2024-08-02 Amarpal Sahota , Amber Roguski , Matthew W Jones , Zahraa S. Abdallah , Raul Santos-Rodriguez

Accurately diagnosing sleep disorders is essential for clinical assessments and treatments. Polysomnography (PSG) has long been used for detection of various sleep disorders. In this research, electrocardiography (ECG) and electromayography…

Sleep staging is essential for the assessment of sleep quality and the diagnosis of sleep-related disorders. Conventional polysomnography (PSG), while considered the gold standard, is intrusive, labor-intensive, and unsuitable for long-term…

信号处理 · 电气工程与系统科学 2026-04-21 Zhuo Diao , Yueting Li , Jianpeng Wang , Shengyu Guan , Xinwei Wang , Wenxiong Cui , Xin Shi , Tong Liu , Kailai Sun , Jingyu Wang , Dian Fan , Thomas Penzel

Mental disorders present challenges in diagnosis and treatment due to their complex and heterogeneous nature. Electroencephalogram (EEG) has shown promise as a potential biomarker for these disorders. However, existing methods for analyzing…

统计方法学 · 统计学 2024-01-30 Xingche Guo , Bin Yang , Ji Meng Loh , Qinxia Wang , Yuanjia Wang

Parkinson's disease (PD) is a progressive neurodegenerative disorder that results in a variety of motor dysfunction symptoms, including tremors, bradykinesia, rigidity and postural instability. The diagnosis of PD mainly relies on clinical…

计算机视觉与模式识别 · 计算机科学 2022-07-15 Haozheng Zhang , Edmond S. L. Ho , Xiatian Zhang , Hubert P. H. Shum

This study proposes a novel lightweight neural network model leveraging features extracted from electrocardiogram (ECG) and respiratory signals for early OSA screening. ECG signals are used to generate feature spectrograms to predict sleep…

机器学习 · 计算机科学 2025-01-06 Hui Pan , Yanxuan Yu , Jilun Ye , Xu Zhang

Preprint Note: This is the author preprint version of a paper accepted for presentation at the IISE Annual Conference & Expo 2025. The final version will appear in the official proceedings. Diabetic retinopathy (DR) is a leading cause of…

机器学习 · 计算机科学 2025-10-02 Mahyar Mahmoudi , Tieming Liu