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Despite the tremendous progresses in wavefront control through or inside complex scattering media, several limitations prevent reaching practical feasibility for nonlinear imaging in biological tissues. While the optimization of nonlinear…

光学 · 物理学 2016-12-06 Hilton B. de Aguiar , Sylvain Gigan , Sophie Brasselet

Over the past decade, optical wavefront shaping has been developed to focus light through highly opaque scattering layers, opening new possibilities for biomedical applications. To probe light intensity deep inside soft scattering media…

光学 · 物理学 2025-08-25 Fei Xia , Ivo Leite , Robert Prevedel , Thomas Chaigne

We derive analytical expressions to describe how light is frequency-shifted when interacting with ultrasound within scattering media, due to the modulation of the refractive index induced by the ultrasound pressure waves. The model is…

光学 · 物理学 2024-10-16 Adam Kinos

Deep, high-resolution imaging is essential for unraveling biological complexity and advancing medical diagnostics, yet scattering fundamentally limits optical methods. Among the most promising approaches, photoacoustic imaging achieves…

Optical microscopy has so far been restricted to superficial layers, leaving many important biological questions unanswered. Random scattering causes the ballistic focus, which is conventionally used for image formation, to decay…

光学 · 物理学 2012-08-28 Ke Si , Reto Fiolka , Meng Cui

Traditional ultrasound simulation methods solve wave equations numerically, achieving high accuracy but at substantial computational cost. Faster alternatives based on convolution with precomputed impulse responses remain relatively slow,…

医学物理 · 物理学 2025-10-14 Felix Duelmer , Mohammad Farid Azampour , Nassir Navab

Modern laser sources nowadays deliver ultrashort light pulses reaching few cycles in duration, high energies beyond the Joule level and peak powers exceeding several terawatt (TW). When such pulses propagate through optically-transparent…

光学 · 物理学 2007-09-27 L. Berge , S. Skupin , R. Nuter , J. Kasparian , J. -P. Wolf

Light scattering in inhomogeneous media induces wavefront distortions which pose an inherent limitation in many optical applications. Examples range from microscopy and nanosurgery to astronomy. In recent years, ongoing efforts have made…

光学 · 物理学 2015-05-20 Ori Katz , Yaron Bromberg , Eran Small , Yaron Silberberg

This work compares computational methods for laser pulse propagation in hollow waveguides filled with rare gases at high pressures, with applications in extreme nonlinear optics in the mid-infrared wavelength region. As the wavelength of…

光学 · 物理学 2013-05-17 Jonathan Andreasen , Miroslav Kolesik

This report introduces the Transfer Waveguide (TRANSGUIDE); an ultra-thin flat technology that promises light emitting applications a practical solution to total internal reflection light trapping and diverging emission. By invoking…

光学 · 物理学 2020-11-17 Hossam Galal

Fundamental to many applications of laser pulses in science and technology is an extended interaction length with matter that significantly exceeds the distance over which the pulse would normally diffract and transversely spread. At low…

等离子体物理 · 物理学 2025-12-10 J. E. Shrock , B. Miao , E. Rockafellow , H. M. Milchberg

Deep-tissue optical imaging is a longstanding challenge limited by scattering. Both optical imaging and treatment can benefit from focusing light in deep tissue beyond one transport mean free path. Wavefront shaping based on time-reversed…

光学 · 物理学 2020-12-09 Juze Zhang , Zijian Gao , Xiaopeng Yu , Peng Ge , Feng Gao , Fei Gao

An extended aperture has the potential to greatly improve ultrasound imaging performance. This work extends the effective aperture size by coherently compounding the received radio frequency data from multiple transducers. A framework is…

Lensless imaging is an elegant approach to high-resolution microscopy, which is rapidly gaining popularity in applications where imaging optics are problematic. However, current lensless imaging methods require objects to be placed within a…

光学 · 物理学 2014-06-16 Stefan Witte , Vasco T. Tenner , Daniël W. E. Noom , Kjeld S. E. Eikema

Optical imaging through scattering media is a fundamental challenge in many applications. Recently, substantial breakthroughs such as imaging through biological tissues and looking around corners have been obtained by the use of…

光学 · 物理学 2020-07-09 Tomer Yeminy , Ori Katz

The field of biomedical imaging has undergone a rapid growth in recent years, mostly due to the implementation of ad-hoc designed experimental setups, theoretical support methods and numerical reconstructions. Especially for biological…

生物物理 · 物理学 2017-06-30 Daniele Ancora

The imaging depth of deep-tissue optical microscopy is governed by the performance of the gating operation that suppresses the multiply scattered waves obscuring the ballistic waves. Although various gating operations based on confocal,…

Sensing and manipulating targets hidden under scattering media are universal problems that take place in applications ranging from deep-tissue optical imaging to laser surgery. A major issue in these applications is the shallow light…

In biological microscopy, light scattering represents the main limitation to image at depth. Recently, a set of wavefront shaping techniques has been developed in order to manipulate coherent light in strongly disordered materials. The…

光学 · 物理学 2021-01-07 Antoine Boniface , Jonathan Dong , Sylvain Gigan

Optical wavefront-shaping has emerged as a powerful tool to manipulate light in strongly scattering media. It enables diffraction-limited focusing and imaging at depths where conventional microscopy techniques fail. However, while most…

光学 · 物理学 2014-03-04 T. Chaigne , O. Katz , A. C. Boccara , M. Fink , E. Bossy , S. Gigan
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