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Parkinson's disease (PD) belongs to the class of neurodegenerative disorders that affect the central nervous system. It is usually defined as the gradual loss of dopaminergic neurons in the substantia nigra pars compacta, which causes both…

神经元与认知 · 定量生物学 2024-11-01 Hina Shaheen , Roderick Melnik

Parkinson's Disease (PD) is one of the most common types of neurological diseases caused by progressive degeneration of dopamin- ergic neurons in the brain. Even though there is no fixed cure for this neurodegenerative disease, earlier…

计算机视觉与模式识别 · 计算机科学 2018-06-21 Sara Soltaninejad , Irene Cheng , Anup Basu

Diagnosis of Parkinson's disease (PD) is commonly based on medical observations and assessment of clinical signs, including the characterization of a variety of motor symptoms. However, traditional diagnostic approaches may suffer from…

机器学习 · 计算机科学 2020-10-14 Jie Mei , Christian Desrosiers , Johannes Frasnelli

Parkinson's disease (PD), the second most prevalent neurodegenerative disorder worldwide, frequently presents with early-stage speech impairments. Recent advancements in Artificial Intelligence (AI), particularly deep learning (DL), have…

声音 · 计算机科学 2024-09-25 Lisanne van Gelderen , Cristian Tejedor-García

Efficient early diagnosis is paramount in addressing the complexities of Parkinson's disease because timely intervention can substantially mitigate symptom progression and improve patient outcomes. In this paper, we present a pioneering…

信号处理 · 电气工程与系统科学 2024-04-25 Alireza Rashnu , Armin Salimi-Badr

Parkinson's disease (PD) is a common and complex neurodegenerative disorder with 5 stages in the Hoehn and Yahr scaling. Given the heterogeneity of PD, it is challenging to classify early stages 1 and 2 and detect brain function…

神经元与认知 · 定量生物学 2022-07-22 Xueqi Guo , Sule Tinaz , Nicha C. Dvornek

Background and Objective: Parkinson's disease (PD) is the second most common progressive neurological condition after Alzheimer's, characterized by motor and non-motor symptoms. Developing a method to diagnose the condition in its beginning…

机器学习 · 计算机科学 2022-10-05 Paria Ghaheri , Hamid Nasiri , Ahmadreza Shateri , Arman Homafar

Parkinsons disease (PD) is considered one of the most frequent neurological diseases in the world. There is a need to study the early and efficient biomarkers of Parkinsons, such as changes in structural disorders like DNA and chromatin,…

Parkinson's Disease (PD) is a degenerative neurological disorder that impairs motor and non-motor functions, significantly reducing quality of life and increasing mortality risk. Early and accurate detection of PD progression is vital for…

机器学习 · 计算机科学 2024-12-31 Abhinav Roy , Bhavesh Gyanchandani , Aditya Oza , Abhishek Sharma

Parkinson's Disease (PD) is a progressive neurodegenerative disorder that significantly impacts both motor and non-motor functions, including speech. Early and accurate recognition of PD through speech analysis can greatly enhance patient…

数值分析 · 数学 2024-07-24 Niloofar Fadavi , Nazanin Fadavi

Parkinson's disease (PD) and Alzheimer's disease (AD) are the two most prevalent and incurable neurodegenerative diseases (NDs) worldwide, for which early diagnosis is critical to delay their progression. However, the high dimensionality of…

计算机视觉与模式识别 · 计算机科学 2026-04-02 Chengjia Liang , Zhenjiong Wang , Chao Chen , Ruizhi Zhang , Songxi Liang , Hai Xie , Haijun Lei , Zhongwei Huang

Accurate early diagnosis and monitoring of neurodegenerative conditions is essential for effective disease management and delivery of medication and treatment. This research develops automatic methods for detecting brain imaging preclinical…

神经与进化计算 · 计算机科学 2019-10-15 Amir Dehsarvi , Stephen L. Smith

Several diseases of parkinsonian syndromes present similar symptoms at early stage and no objective widely used diagnostic methods have been approved until now. Positron emission tomography (PET) with $^{18}$F-FDG was shown to be able to…

Parkinsons disease (PD) is a movement disorder and the second most common neurodengerative disease but despite its relative abundance, there are no clinically accepted neuroimaging biomarkers to make prognostic predictions or differentiate…

神经元与认知 · 定量生物学 2022-06-23 Cooper J. Mellema , Kevin P. Nguyen , Alex Treacher , Aixa Andrade Hernandez , Albert A. Montillo

Parkinson's disease (PD), characterized by its incurable nature, rapid progression, and severe disability, poses significant challenges to the lives of patients and their families. Given the aging population, the need for early detection of…

计算机视觉与模式识别 · 计算机科学 2025-06-24 Wei Huang , Yinxuan Xu , Yintao Zhou , Zhengyu Li , Jing Huang , Meng Pang

Purpose:Current methods for diagnosis of PD rely on clinical examination. The accuracy of diagnosis ranges between 73% and 84%, and is influenced by the experience of the clinical assessor. Hence, an automatic, effective and interpretable…

计算机视觉与模式识别 · 计算机科学 2023-12-22 Haozheng Zhang , Edmond S. L. Ho , Xiatian Zhang , Silvia Del Din , Hubert P. H. Shum

This paper represents a groundbreaking advancement in Parkinson disease (PD) research by employing a novel machine learning framework to categorize PD into distinct subtypes and predict its progression. Utilizing a comprehensive dataset…

机器学习 · 计算机科学 2024-06-12 Ashwin Ram

Drug-induced parkinsonism affects many older adults with dementia, often causing gait disturbances. New advances in vision-based human pose-estimation have opened possibilities for frequent and unobtrusive analysis of gait in residential…

计算机视觉与模式识别 · 计算机科学 2021-10-05 Andrea Sabo , Sina Mehdizadeh , Andrea Iaboni , Babak Taati

PPINtonus is a system for the early detection of Parkinson's Disease (PD) utilizing deep-learning tonal analysis, providing a cost-effective and accessible alternative to traditional neurological examinations. Partnering with the…

音频与语音处理 · 电气工程与系统科学 2024-06-06 Varun Reddy

Parkinson's disease (PD) is a neurodegenerative condition characterized by frequently changing motor symptoms, necessitating continuous symptom monitoring for more targeted treatment. Classical time series classification and deep learning…

机器学习 · 计算机科学 2025-06-03 Cedric Donié , Neha Das , Satoshi Endo , Sandra Hirche