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Cancer forms a robust system and progresses as stages over time typically with increasing aggressiveness and worsening prognosis. Characterizing these stages and identifying the genes driving transitions between them is critical to…

分子网络 · 定量生物学 2014-02-04 Sriganesh Srihari , Venkatesh Raman , Hon Wai Leong , Mark A. Ragan

Lung cancer is the most common form of cancer found worldwide with a high mortality rate. Early detection of pulmonary nodules by screening with a low-dose computed tomography (CT) scan is crucial for its effective clinical management.…

图像与视频处理 · 电气工程与系统科学 2020-06-17 Rakshith Sathish , Rachana Sathish , Ramanathan Sethuraman , Debdoot Sheet

Background Precise prediction of cancer types is vital for cancer diagnosis and therapy. Important cancer marker genes can be inferred through predictive model. Several studies have attempted to build machine learning models for this task…

基因组学 · 定量生物学 2019-06-20 Milad Mostavi , Yu-Chiao Chiu , Yufei Huang , Yidong Chen

Cancer is a fatal disease caused by a combination of genetic diseases and a variety of biochemical abnormalities. Lung and colon cancer have emerged as two of the leading causes of death and disability in humans. The histopathological…

图像与视频处理 · 电气工程与系统科学 2022-06-06 Md. Alamin Talukder , Md. Manowarul Islam , Md Ashraf Uddin , Arnisha Akhter , Khondokar Fida Hasan , Mohammad Ali Moni

Lung cancer is a leading cause of cancer-related deaths globally, where early detection and accurate diagnosis are critical for improving survival rates. While deep learning, particularly convolutional neural networks (CNNs), has…

图像与视频处理 · 电气工程与系统科学 2025-05-15 Sadman Sakib Alif , Nasim Anzum Promise , Fiaz Al Abid , Aniqua Nusrat Zereen

MicroRNAs play an indispensable role in numerous biological processes ranging from organismic development to tumor progression.In oncology,these microRNAs constitute a fundamental regulation role in the pathology of cancer that provides the…

定量方法 · 定量生物学 2022-01-17 Dietrich Kong , Ke Wang , Qiu-Ning Zhang , Zhi-Tong Bing

Stratifying cancer patients based on their gene expression levels allows improving diagnosis, survival analysis and treatment planning. However, such data is extremely highly dimensional as it contains expression values for over 20000 genes…

Lung cancer is the leading reason behind cancer-related deaths within the world. Early detection of lung nodules is vital for increasing the survival rate of cancer patients. Traditionally, physicians should manually identify the world…

图像与视频处理 · 电气工程与系统科学 2023-05-31 Hasan Hejbari Zargar , Saha Hejbari Zargar , Raziye Mehri , Farzane Tajidini

Insufficiently precise diagnosis of clinical disease is likely responsible for many treatment failures, even for common conditions and treatments. With a large enough dataset, it may be possible to use unsupervised machine learning to…

Detecting malignant pulmonary nodules at an early stage can allow medical interventions which may increase the survival rate of lung cancer patients. Using computer vision techniques to detect nodules can improve the sensitivity and the…

图像与视频处理 · 电气工程与系统科学 2020-10-30 Siqi Liu , Arnaud Arindra Adiyoso Setio , Florin C. Ghesu , Eli Gibson , Sasa Grbic , Bogdan Georgescu , Dorin Comaniciu

Accurate tumor staging in lung cancer is crucial for prognosis and treatment planning and is governed by explicit anatomical criteria under fixed guidelines. However, most existing deep learning approaches treat this spatially structured…

This work studies lung tumor growth prediction from sparse and irregular longitudinal computed tomography (CT) observations with measurement variability. A Bayesian physics-informed neural network is developed by combining Gompertz growth…

机器学习 · 计算机科学 2026-05-14 Lingfei Kong , Haoran Ma

Transcriptional profiling on microarrays to obtain gene expressions has been used to facilitate cancer diagnosis. We propose a deep generative machine learning architecture (called DeepCancer) that learn features from unlabeled microarray…

人工智能 · 计算机科学 2016-12-14 Rajendra Rana Bhat , Vivek Viswanath , Xiaolin Li

In the current technological era, the medical profession has emerged as one of the researchers' favorite subject areas, and cancer is one of them. Because there is now no effective treatment for this illness, it is a matter of concern. Only…

机器学习 · 计算机科学 2024-10-23 Praneeth Kumar T , Nidhi Srivastava , Rakshith Mahishi , Chayadevi M L

BACKGROUND: Breast cancer has emerged as one of the most prevalent cancers among women leading to a high mortality rate. Due to the heterogeneous nature of breast cancer, there is a need to identify differentially expressed genes associated…

机器学习 · 计算机科学 2021-11-30 Sheetal Rajpal , Ankit Rajpal , Manoj Agarwal , Naveen Kumar

In high-dimensional data settings, additional information on the features is often available. Examples of such external information in omics research are: (a) p-values from a previous study, (b) a summary of prior information, and (c) omics…

统计方法学 · 统计学 2024-08-20 Magnus M. Münch , Carel F. W. Peeters , Aad W. van der Vaart , Mark A. van de Wiel

Classification is one of the major issues in Data Mining Research fields. The classification problems in medical area often classify medical dataset based on the result of medical diagnosis or description of medical treatment by the medical…

人工智能 · 计算机科学 2013-01-09 N. Kalaiselvi , H. Hannah Inbarani

Early detection of lung cancer is an effective way to improve the survival rate of patients. It is a critical step to have accurate detection of lung nodules in computed tomography (CT) images for the diagnosis of lung cancer. However, due…

计算机视觉与模式识别 · 计算机科学 2019-05-10 Haichao Cao , Hong Liu , Enmin Song , Guangzhi Ma , Xiangyang Xu , Renchao Jin , Tengying Liu , Chih-Cheng Hung

Early and accurate diagnosis of interstitial lung diseases (ILDs) is crucial for making treatment decisions, but can be challenging even for experienced radiologists. The diagnostic procedure is based on the detection and recognition of the…

计算机视觉与模式识别 · 计算机科学 2018-04-02 Marios Anthimopoulos , Stergios Christodoulidis , Lukas Ebner , Thomas Geiser , Andreas Christe , Stavroula Mougiakakou

Accurate and efficient classification of different types of cancer is critical for early detection and effective treatment. In this paper, we present the results of our experiments using the EfficientNet algorithm for classification of…

图像与视频处理 · 电气工程与系统科学 2023-07-14 Romario Sameh Samir