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Cellular processes are governed by macromolecular complexes inside the cell. Study of the native structures of macromolecular complexes has been extremely difficult due to lack of data. With recent breakthroughs in Cellular electron cryo…

定量方法 · 定量生物学 2018-06-12 Chengqian Che , Ruogu Lin , Xiangrui Zeng , Karim Elmaaroufi , John Galeotti , Min Xu

Motivation: Cellular Electron CryoTomography (CECT) enables 3D visualization of cellular organization at near-native state and in sub-molecular resolution, making it a powerful tool for analyzing structures of macromolecular complexes and…

定量方法 · 定量生物学 2017-04-14 Min Xu , Xiaoqi Chai , Hariank Muthakana , Xiaodan Liang , Ge Yang , Tzviya Zeev-Ben-Mordehai , Eric Xing

Electron Cryo-Tomography (ECT) enables 3D visualization of macromolecule structure inside single cells. Macromolecule classification approaches based on convolutional neural networks (CNN) were developed to separate millions of…

定量方法 · 定量生物学 2018-03-28 Jialiang Guo , Bo Zhou , Xiangrui Zeng , Zachary Freyberg , Min Xu

Deep learning models have gained remarkable performance on a variety of image classification tasks. However, many models suffer from limited performance in clinical or medical settings when data are imbalanced. To address this challenge, we…

图像与视频处理 · 电气工程与系统科学 2022-04-15 Long Gao , Chang Liu , Dooman Arefan , Ashok Panigrahy , Margarita L. Zuley , Shandong Wu

Cellular Electron Cryo-Tomography (CECT) is a powerful imaging technique for the 3D visualization of cellular structure and organization at submolecular resolution. It enables analyzing the native structures of macromolecular complexes and…

定量方法 · 定量生物学 2018-05-16 Chang Liu , Xiangrui Zeng , Ruogu Lin , Xiaodan Liang , Zachary Freyberg , Eric Xing , Min Xu

Motivation: Cryo-Electron Tomography (cryo-ET) is a 3D bioimaging tool that visualizes the structural and spatial organization of macromolecules at a near-native state in single cells, which has broad applications in life science. However,…

定量方法 · 定量生物学 2021-07-28 Xuefeng Du , Haohan Wang , Zhenxi Zhu , Xiangrui Zeng , Yi-Wei Chang , Jing Zhang , Min Xu

Without any specific way for imbalance data classification, artificial intelligence algorithm cannot recognize data from minority classes easily. In general, modifying the existing algorithm by assuming that the training data is imbalanced,…

机器学习 · 计算机科学 2018-07-16 Fanny , Tjeng Wawan Cenggoro

Precise breast cancer classification on histopathological images has the potential to greatly improve the diagnosis and patient outcome in oncology. The data imbalance problem largely stems from the inherent imbalance within medical image…

图像与视频处理 · 电气工程与系统科学 2024-11-28 Majid Behzadpour , Bengie L. Ortiz , Ebrahim Azizi , Kai Wu

Training models on highly unbalanced data is admitted to be a challenging task for machine learning algorithms. Current studies on deep learning mainly focus on data sets with balanced class labels or unbalanced data, but with massive…

机器学习 · 计算机科学 2020-02-27 Louis Marceau , Lingling Qiu , Nick Vandewiele , Eric Charton

Cellular Electron Cryo-Tomography (CECT) is a powerful 3D imaging tool for studying the native structure and organization of macromolecules inside single cells. For systematic recognition and recovery of macromolecular structures captured…

计算机视觉与模式识别 · 计算机科学 2018-07-04 Chang Liu , Xiangrui Zeng , Kaiwen Wang , Qiang Guo , Min Xu

Data in real-world application often exhibit skewed class distribution which poses an intense challenge for machine learning. Conventional classification algorithms are not effective in the case of imbalanced data distribution, and may fail…

机器学习 · 计算机科学 2019-01-08 Enlu Lin , Qiong Chen , Xiaoming Qi

Improving the classification of multi-class imbalanced data is more difficult than its two-class counterpart. In this paper, we use deep neural networks to train new representations of tabular multi-class data. Unlike the typically…

机器学习 · 计算机科学 2023-12-19 Damian Horna , Lango Mateusz , Jerzy Stefanowski

Deep learning has emerged as a prominent field in recent literature, showcasing the introduction of models that utilize transfer learning to achieve remarkable accuracies in the classification of brain tumor MRI images. However, the…

计算机视觉与模式识别 · 计算机科学 2023-08-15 Raza Imam , Mohammed Talha Alam

In this study, we systematically investigate the impact of class imbalance on classification performance of convolutional neural networks (CNNs) and compare frequently used methods to address the issue. Class imbalance is a common problem…

计算机视觉与模式识别 · 计算机科学 2018-10-16 Mateusz Buda , Atsuto Maki , Maciej A. Mazurowski

Motivation: Cryo-Electron Tomography (cryo-ET) visualizes structure and spatial organization of macromolecules and their interactions with other subcellular components inside single cells in the close-to-native state at sub-molecular…

定量方法 · 定量生物学 2020-07-31 Liangyong Yu , Ran Li , Xiangrui Zeng , Hongyi Wang , Jie Jin , Ge Yang , Rui Jiang , Min Xu

Learning from imbalanced data is one of the most significant challenges in real-world classification tasks. In such cases, neural networks performance is substantially impaired due to preference towards the majority class. Existing…

机器学习 · 计算机科学 2022-11-13 Bronislav Yasinnik , Moshe Salhov , Ofir Lindenbaum , Amir Averbuch

Melanoma is a fatal skin cancer that is curable and has dramatically increasing survival rate when diagnosed at early stages. Learning-based methods hold significant promise for the detection of melanoma from dermoscopic images. However,…

图像与视频处理 · 电气工程与系统科学 2022-04-06 Saban Ozturk , Tolga Cukur

Despite extensive research spanning several decades, class imbalance is still considered a profound difficulty for both machine learning and deep learning models. While data oversampling is the foremost technique to address this issue,…

机器学习 · 计算机科学 2025-02-12 Sukumar Kishanthan , Asela Hevapathige

With the rapid growth of memory and computing power, datasets are becoming increasingly complex and imbalanced. This is especially severe in the context of clinical data, where there may be one rare event for many cases in the majority…

Deep Learning methods have significantly advanced various data-driven tasks such as regression, classification, and forecasting. However, much of this progress has been predicated on the strong but often unrealistic assumption that training…

机器学习 · 计算机科学 2023-10-12 Josias Moukpe
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