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Alzheimer's disease (AD) is a progressive and incurable neurodegenerative disease which destroys brain cells and causes loss to patient's memory. An early detection can prevent the patient from further damage of the brain cells and hence…

图像与视频处理 · 电气工程与系统科学 2021-01-11 Ali Nawaz , Syed Muhammad Anwar , Rehan Liaqat , Javid Iqbal , Ulas Bagci , Muhammad Majid

Deep learning has shown superb performance in detecting objects and classifying images, ensuring a great promise for analyzing medical imaging. Translating the success of deep learning to medical imaging, in which doctors need to understand…

Autism Spectrum Disorder (ASD) is a complex neurological condition characterized by varied developmental impairments, especially in communication and social interaction. Accurate and early diagnosis of ASD is crucial for effective…

机器学习 · 计算机科学 2025-03-18 Suchanuch Piriyasatit , Chaohao Yuan , Ercan Engin Kuruoglu

Deep Neural Networks (DNNs) deliver state-of-the-art performance in many image recognition and understanding applications. However, despite their outstanding performance, these models are black-boxes and it is hard to understand how they…

计算机视觉与模式识别 · 计算机科学 2019-08-14 Moustafa Alzantot , Amy Widdicombe , Simon Julier , Mani Srivastava

Alzheimer's disease (AD) has a complex and multifactorial etiology, which requires integrating information about neuroanatomy, genetics, and cerebrospinal fluid biomarkers for accurate diagnosis. Hence, recent deep learning approaches…

机器学习 · 计算机科学 2023-03-15 Tom Nuno Wolf , Sebastian Pölsterl , Christian Wachinger

The increasing use of deep learning across various domains highlights the importance of understanding the decision-making processes of these black-box models. Recent research focusing on the decision boundaries of deep classifiers, relies…

We propose an integrated deep-generative framework, that jointly models complementary information from resting-state functional MRI (rs-fMRI) connectivity and diffusion tensor imaging (DTI) tractography to extract predictive biomarkers of a…

Automated skin lesion classification using deep learning has shown remarkable accuracy, yet clinical adoption remains limited due to the "black box" nature of these models. We present MelanomaNet, an explainable deep learning system for…

计算机视觉与模式识别 · 计算机科学 2025-12-11 Sukhrobbek Ilyosbekov

Machine learning solutions for pattern classification problems are nowadays widely deployed in society and industry. However, the lack of transparency and accountability of most accurate models often hinders their safe use. Thus, there is a…

机器学习 · 计算机科学 2021-12-24 Gonzalo Nápoles , Yamisleydi Salgueiro , Isel Grau , Maikel Leon Espinosa

Identifying objective neuroimaging biomarkers to forecast Alzheimer's disease (AD) progression is crucial for timely intervention. However, this task remains challenging due to the complex dysfunctions in the spatio-temporal characteristics…

In many practical applications, deep neural networks have been typically deployed to operate as a black box predictor. Despite the high amount of work on interpretability and high demand on the reliability of these systems, they typically…

人工智能 · 计算机科学 2020-12-07 Martin Stano , Wanda Benesova , Lukas Samuel Martak

We present an approach to model time series data from resting state fMRI for autism spectrum disorder (ASD) severity classification. We propose to adopt kernel machines and employ graph kernels that define a kernel dot product between two…

机器学习 · 统计学 2016-12-04 Rushil Anirudh , Jayaraman J. Thiagarajan , Irene Kim , Wolfgang Polonik

Digital mammography is essential to breast cancer detection, and deep learning offers promising tools for faster and more accurate mammogram analysis. In radiology and other high-stakes environments, uninterpretable ("black box") deep…

计算机视觉与模式识别 · 计算机科学 2024-06-11 Julia Yang , Alina Jade Barnett , Jon Donnelly , Satvik Kishore , Jerry Fang , Fides Regina Schwartz , Chaofan Chen , Joseph Y. Lo , Cynthia Rudin

As the prevalence of Alzheimer's disease (AD) rises, improving mechanistic insight from non-invasive biomarkers is increasingly critical. Recent work suggests that circuit-level brain alterations manifest as changes in…

神经与进化计算 · 计算机科学 2026-02-10 Szymon Mamoń , Max Talanov , Alessandro Crimi

Alzheimer's Disease (AD) detection employs machine learning classification models to distinguish between individuals with AD and those without. Different from conventional classification tasks, we identify within-class variation as a…

音频与语音处理 · 电气工程与系统科学 2025-09-29 Jiawen Kang , Dongrui Han , Lingwei Meng , Jingyan Zhou , Jinchao Li , Xixin Wu , Helen Meng

Anomaly detection (AD) is the identification of data samples that do not fit a learned data distribution. As such, AD systems can help physicians to determine the presence, severity, and extension of a pathology. Deep generative models,…

图像与视频处理 · 电气工程与系统科学 2021-04-12 Jaime Simarro , Ezequiel de la Rosa , Thijs Vande Vyvere , David Robben , Diana M. Sima

Alzheimer's disease (AD) is a progressive brain disorder that causes memory and functional impairments. The advances in machine learning and publicly available medical datasets initiated multiple studies in AD diagnosis. In this work, we…

图像与视频处理 · 电气工程与系统科学 2021-07-20 Aidana Massalimova , Huseyin Atakan Varol

Purpose: Hard-to-interpret Black-box Machine Learning (ML) were often used for early Alzheimer's Disease (AD) detection. Methods: To interpret eXtreme Gradient Boosting (XGBoost), Random Forest (RF), and Support Vector Machine (SVM)…

机器学习 · 计算机科学 2022-11-08 Louise Bloch , Christoph M. Friedrich

With the availability of large databases and recent improvements in deep learning methodology, the performance of AI systems is reaching or even exceeding the human level on an increasing number of complex tasks. Impressive examples of this…

人工智能 · 计算机科学 2017-08-29 Wojciech Samek , Thomas Wiegand , Klaus-Robert Müller

We propose a unified optimization framework that combines neural networks with dictionary learning to model complex interactions between resting state functional MRI and behavioral data. The dictionary learning objective decomposes patient…