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Many important tasks of large-scale recommender systems can be naturally cast as testing multiple linear forms for noisy matrix completion. These problems, however, present unique challenges because of the subtle bias-and-variance tradeoff…

统计方法学 · 统计学 2025-03-12 Wanteng Ma , Lilun Du , Dong Xia , Ming Yuan

Large-scale hypothesis testing is central to modern science, where controlling the False Discovery Rate (FDR) has become the standard approach to managing false positives across many simultaneous tests. Hypotheses rarely exist in isolation;…

统计方法学 · 统计学 2026-05-19 Binyamin Perets , Shie Mannor

The False Discovery Rate (FDR) is a new statistical procedure to control the number of mistakes made when performing multiple hypothesis tests, i.e. when comparing many data against a given model hypothesis. The key advantage of FDR is that…

Controlling False Discovery Rate (FDR) while leveraging the side information of multiple hypothesis testing is an emerging research topic in modern data science. Existing methods rely on the test-level covariates while ignoring metrics…

机器学习 · 统计学 2022-10-10 Lin Qiu , Nils Murrugarra-Llerena , Vítor Silva , Lin Lin , Vernon M. Chinchilli

False discovery rate (FDR) procedures provide misleading inference when testing multiple null hypotheses with heterogeneous multinomial data. For example, in the motivating study the goal is to identify species of bacteria near the roots of…

统计方法学 · 统计学 2015-11-05 Joshua Habiger , David Watts , Michael Anderson

We consider a multi-object detection problem over a sensor network (SNET) with limited range sensors. This problem complements the widely considered decentralized detection problem where all sensors observe the same object. While the…

信息论 · 计算机科学 2016-11-17 Erhan B. Ermis , Venkatesh Saligrama

Thanks to its fine balance between model flexibility and interpretability, the nonparametric additive model has been widely used, and variable selection for this type of model has been frequently studied. However, none of the existing…

统计方法学 · 统计学 2022-01-10 Xiaowu Dai , Xiang Lyu , Lexin Li

Multiple testing with false discovery rate (FDR) control has been widely conducted in the ``discrete paradigm" where p-values have discrete and heterogeneous null distributions. However, in this scenario existing FDR procedures often lose…

统计方法学 · 统计学 2019-07-23 Xiongzhi Chen , R. W. Doerge , Sanat K. Sarkar

Motivation: Accurate estimation of false discovery rate (FDR) of spectral identification is a central problem in mass spectrometry-based proteomics. Over the past two decades, target decoy approaches (TDAs) and decoy-free approaches (DFAs),…

定量方法 · 定量生物学 2020-09-18 Yisu Peng , Shantanu Jain , Yong Fuga Li , Michal Gregus , Alexander R. Ivanov , Olga Vitek , Predrag Radivojac

In many fields of science, we observe a response variable together with a large number of potential explanatory variables, and would like to be able to discover which variables are truly associated with the response. At the same time, we…

统计方法学 · 统计学 2015-10-15 Rina Foygel Barber , Emmanuel J. Candès

We propose a novel multiple testing methodology for controlling the false discovery rate (FDR) in high-dimensional linear models that integrates model-X knockoff techniques with debiased penalized regression estimators. At the foundation of…

统计方法学 · 统计学 2026-03-17 Jinyuan Chang , Chenlong Li , Cheng Yong Tang , Zhengtian Zhu

Barber and Cand\`es (2015) control of the FDR in feature selection relies on estimating the FDR by the number of knockoff wins +1 divided by the number of original wins. We study the necessity of the +1 in general settings.

统计方法学 · 统计学 2024-12-10 Andrew Rajchert , Uri Keich

A systematic multiple hypothesis testing approach is applied to the search for astrophysical sources of high energy neutrinos. The method is based on the maximisation of the detection power maintaining the control of the confidence level of…

天体物理仪器与方法 · 物理学 2010-11-24 Bruny Baret , Mathieu Labare , Daniel Bertrand

The multiple testing procedure plays an important role in detecting the presence of spatial signals for large-scale imaging data. Typically, the spatial signals are sparse but clustered. This paper provides empirical evidence that for a…

统计理论 · 数学 2011-03-11 Chunming Zhang , Jianqing Fan , Tao Yu

Multiple hypothesis testing, a situation when we wish to consider many hypotheses, is a core problem in statistical inference that arises in almost every scientific field. In this setting, controlling the false discovery rate (FDR), which…

统计理论 · 数学 2019-03-19 Shiyun Chen , Shiva Kasiviswanathan

We tackle the problem of selecting from among a large number of variables those that are 'important' for an outcome. We consider situations where groups of variables are also of interest in their own right. For example, each variable might…

统计方法学 · 统计学 2018-08-13 Eugene Katsevich , Chiara Sabatti

We propose the use of a new false discovery rate (FDR) controlling procedure as a model selection penalized method, and compare its performance to that of other penalized methods over a wide range of realistic settings: nonorthogonal design…

应用统计 · 统计学 2009-05-19 Yoav Benjamini , Yulia Gavrilov

As in many other scientific domains, we face a fundamental problem when using machine learning to identify proteins from mass spectrometry data: large ground truth datasets mapping inputs to correct outputs are extremely difficult to…

False discovery rate (FDR) is a common way to control the number of false discoveries in multiple testing. There are a number of approaches available for controlling FDR. However, for functional test statistics, which are discretized into…

统计方法学 · 统计学 2024-12-03 Tomáš Mrkvička , Mari Myllymäki

Conventional multiple testing procedures often assume hypotheses for different features are exchangeable. However, in many scientific applications, additional covariate information regarding the patterns of signals and nulls are available.…

统计方法学 · 统计学 2020-06-12 Xianyang Zhang , Jun Chen