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Background fluorescence, especially when it exhibits undesired spatial features, is a primary factor for reduced image quality in optical microscopy. Structured background is particularly detrimental when analyzing single-molecule images…

光学 · 物理学 2020-03-25 Leonhard Möckl , Anish R. Roy , Petar N. Petrov , W. E. Moerner

The goal of our research is to develop methods advancing automatic visual recognition. In order to predict the unique or multiple labels associated to an image, we study different kind of Deep Neural Networks architectures and methods for…

计算机视觉与模式识别 · 计算机科学 2016-10-19 Rémi Cadène , Nicolas Thome , Matthieu Cord

This paper proposes a robust localization system that employs deep learning for better scene representation, and enhances the accuracy of 6-DOF camera pose estimation. Inspired by the fact that global scene structure can be revealed by wide…

计算机视觉与模式识别 · 计算机科学 2019-04-23 Hsin-I Chen , Sebastian Agethen , Chiamin Wu , Winston Hsu , Bing-Yu Chen

Fluorescence microscopy allows for a detailed inspection of cells, cellular networks, and anatomical landmarks by staining with a variety of carefully-selected markers visualized as color channels. Quantitative characterization of…

计算机视觉与模式识别 · 计算机科学 2021-08-26 Alvaro Gomariz , Tiziano Portenier , Patrick M. Helbling , Stephan Isringhausen , Ute Suessbier , César Nombela-Arrieta , Orcun Goksel

Software fault localization remains challenging due to limited feature diversity and low precision in traditional methods. This paper proposes a novel approach that integrates multi-objective optimization with deep learning models to…

软件工程 · 计算机科学 2024-11-27 Xiaolei Hu , Dongcheng Li , W. Eric Wong , Ya Zou

Super-resolution microscopy has catalyzed valuable insights into the sub-cellular, mechanistic details of many different biological processes across a wide range of cell types. Fluorescence polarization spectroscopy tools have also enabled…

生物物理 · 物理学 2023-01-25 Jack W Shepherd , Alex L Payne-Dwyer , Ji-Eun Lee , Aisha Syeda , Mark C Leake

A significant research problem of recent interest is the localization of targets like vessels, surgical needles, and tumors in photoacoustic (PA) images. To achieve accurate localization, a high photoacoustic signal-to-noise ratio (SNR) is…

图像与视频处理 · 电气工程与系统科学 2021-05-03 Amirsaeed Yazdani , Sumit Agrawal , Kerrick Johnstonbaugh , Sri-Rajasekhar Kothapalli , Vishal Monga

Protein function is inherently linked to its localization within the cell, and fluorescent microscopy data is an indispensable resource for learning representations of proteins. Despite major developments in molecular representation…

定量方法 · 定量生物学 2022-05-25 Anastasia Razdaibiedina , Alexander Brechalov

Recently, super-resolution ultrasound imaging with ultrasound localization microscopy (ULM) has received much attention. However, ULM relies on low concentrations of microbubbles in the blood vessels, ultimately resulting in long…

Methods that combine local and global features have recently shown excellent performance on multiple challenging deep image retrieval benchmarks, but their use of local features raises at least two issues. First, these local features simply…

计算机视觉与模式识别 · 计算机科学 2022-02-01 Philippe Weinzaepfel , Thomas Lucas , Diane Larlus , Yannis Kalantidis

Error backpropagation is a highly effective mechanism for learning high-quality hierarchical features in deep networks. Updating the features or weights in one layer, however, requires waiting for the propagation of error signals from…

神经与进化计算 · 计算机科学 2017-11-21 Hesham Mostafa , Vishwajith Ramesh , Gert Cauwenberghs

Single molecule localization microscopy is a recently developed superresolution imaging technique to visualize structural properties of single cells. The basic principle consists in chemically attaching fluorescent dyes to the molecules,…

Object segmentation and structure localization are important steps in automated image analysis pipelines for microscopy images. We present a convolution neural network (CNN) based deep learning architecture for segmentation of objects in…

计算机视觉与模式识别 · 计算机科学 2019-01-24 Shan E Ahmed Raza , Linda Cheung , Muhammad Shaban , Simon Graham , David Epstein , Stella Pelengaris , Michael Khan , Nasir M. Rajpoot

Learning-based single image super-resolution (SISR) methods are continuously showing superior effectiveness and efficiency over traditional model-based methods, largely due to the end-to-end training. However, different from model-based…

图像与视频处理 · 电气工程与系统科学 2020-03-24 Kai Zhang , Luc Van Gool , Radu Timofte

Three-dimensional (3D) fluorescence microscopy in general requires axial scanning to capture images of a sample at different planes. Here we demonstrate that a deep convolutional neural network can be trained to virtually refocus a 2D…

计算机视觉与模式识别 · 计算机科学 2019-11-05 Yichen Wu , Yair Rivenson , Hongda Wang , Yilin Luo , Eyal Ben-David , Laurent A. Bentolila , Christian Pritz , Aydogan Ozcan

Fluorescence microscopy is essential to study biological structures and dynamics. However, existing systems suffer from a tradeoff between field-of-view (FOV), resolution, and complexity, and thus cannot fulfill the emerging need of…

光学 · 物理学 2022-09-09 Yujia Xue , Qianwan Yang , Guorong Hu , Kehan Guo , Lei Tian

Counting cells in fluorescent microscopy is a tedious, time-consuming task that researchers have to accomplish to assess the effects of different experimental conditions on biological structures of interest. Although such objects are…

计算机视觉与模式识别 · 计算机科学 2021-03-02 R. Morelli , L. Clissa , M. Dalla , M. Luppi , L. Rinaldi , A. Zoccoli

We propose approaches based on deep learning to localize objects in images when only a small training dataset is available and the images have low quality. That applies to many problems in medical image processing, and in particular to the…

计算机视觉与模式识别 · 计算机科学 2018-11-20 Aaron Pries , Peter J. Schreier , Artur Lamm , Stefan Pede , Jürgen Schmidt

Traditional deep network training methods optimize a monolithic objective function jointly for all the components. This can lead to various inefficiencies in terms of potential parallelization. Local learning is an approach to…

机器学习 · 计算机科学 2023-01-19 Adeetya Patel , Michael Eickenberg , Eugene Belilovsky

Visual localization is the task of estimating camera pose in a known scene, which is an essential problem in robotics and computer vision. However, long-term visual localization is still a challenge due to the environmental appearance…

机器人学 · 计算机科学 2022-12-02 Yuxuan Chen , Timothy D. Barfoot