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Short-term synaptic plasticity (STP) is often regarded as a presynaptic filter of spikes, independent of postsynaptic activity. Recent experiments, however, indicate an associative STP that depends on pre- and postsynaptic coactivation. We…

神经元与认知 · 定量生物学 2026-05-20 Genki Shimizu , Taro Toyoizumi

Short-term plasticity (STP) is a mechanism that stores decaying memories in synapses of the cerebral cortex. In computing practice, STP has been used, but mostly in the niche of spiking neurons, even though theory predicts that it is the…

神经与进化计算 · 计算机科学 2023-08-03 Hector Garcia Rodriguez , Qinghai Guo , Timoleon Moraitis

General results from statistical learning theory suggest to understand not only brain computations, but also brain plasticity as probabilistic inference. But a model for that has been missing. We propose that inherently stochastic features…

神经与进化计算 · 计算机科学 2016-02-17 David Kappel , Stefan Habenschuss , Robert Legenstein , Wolfgang Maass

The brain has the phenomenal ability to reorganize itself by forming new connections among neurons and by pruning others. The so-called neural or brain plasticity facilitates the modification of brain structure and function over different…

The synaptic connectivity of cortex is plastic, with experience shaping the ongoing interactions between neurons. Theoretical studies of spike timing-dependent plasticity (STDP) have focused on either just pairs of neurons or large-scale…

神经元与认知 · 定量生物学 2016-08-02 Gabriel Koch Ocker , Brent Doiron

Synaptic plasticity allows cortical circuits to learn new tasks and to adapt to changing environments. How do cortical circuits use plasticity to acquire functions such as decision-making or working memory? Neurons are connected in complex…

神经元与认知 · 定量生物学 2023-03-08 Néstor Parga , Luis Serrano-Fernández , Joan Falcó-Roget

Memory is often defined as the mental capacity of retaining information about facts, events, procedures and more generally about any type of previous experience. Memories are remembered as long as they influence our thoughts, feelings, and…

神经元与认知 · 定量生物学 2017-06-16 Stefano Fusi

The impressive lifelong learning in animal brains is primarily enabled by plastic changes in synaptic connectivity. Importantly, these changes are not passive, but are actively controlled by neuromodulation, which is itself under the…

神经与进化计算 · 计算机科学 2021-07-06 Thomas Miconi , Aditya Rawal , Jeff Clune , Kenneth O. Stanley

Spike-timing-dependent plasticity(STDP) is a biological process of synaptic modification caused by the difference of firing order and timing between neurons. One of the neurodynamical roles of STDP is to form a macroscopic geometrical…

神经元与认知 · 定量生物学 2021-08-10 Hong-Gyu Yoon , Pilwon Kim

To learn useful dynamics on long time scales, neurons must use plasticity rules that account for long-term, circuit-wide effects of synaptic changes. In other words, neural circuits must solve a credit assignment problem to appropriately…

神经元与认知 · 定量生物学 2019-05-30 Owen Marschall , Kyunghyun Cho , Cristina Savin

Synaptic plasticity dynamically shapes the connectivity of neural systems and is key to learning processes in the brain. To what extent the mechanisms of plasticity can be exploited to drive a neural network and make it perform some kind of…

神经元与认知 · 定量生物学 2024-12-03 Francesco Borra , Simona Cocco , Rémi Monasson

A growing body of research indicates that structural plasticity mechanisms are crucial for learning and memory consolidation. Starting from a simple phenomenological model, we exploit a mean-field approach to develop a theoretical framework…

神经元与认知 · 定量生物学 2024-06-19 Gianmarco Tiddia , Luca Sergi , Bruno Golosio

Plasticity is one of the most important properties of the nervous system, which enables animals to adjust their behavior to the ever-changing external environment. Changes in synaptic efficacy between neurons constitute one of the major…

神经元与认知 · 定量生物学 2018-01-23 Taishi Iwasaki , Hideitsu Hino , Masami Tatsuno , Shotaro Akaho , Noboru Murata

One of the defining features of living systems is their adaptability to changing environmental conditions. This requires organisms to extract temporal and spatial features of their environment, and use that information to compute the…

神经元与认知 · 定量生物学 2024-02-27 Maria Sol Vidal-Saez , Oscar Vilarroya , Jordi Garcia-Ojalvo

Storage and retrieval of data in a computer memory plays a major role in system performance. Traditionally, computer memory organization is static - i.e., they do not change based on the application-specific characteristics in memory access…

人工智能 · 计算机科学 2021-01-11 Prabuddha Chakraborty , Swarup Bhunia

Continuous adaptation allows survival in an ever-changing world. Adjustments in the synaptic coupling strength between neurons are essential for this capability, setting us apart from simpler, hard-wired organisms. How these changes can be…

神经元与认知 · 定量生物学 2021-01-06 Jakob Jordan , Maximilian Schmidt , Walter Senn , Mihai A. Petrovici

Neural plasticity is an important functionality of human brain, in which number of neurons and synapses can shrink or expand in response to stimuli throughout the span of life. We model this dynamic learning process as an $L_0$-norm…

神经与进化计算 · 计算机科学 2021-05-04 Yang Li , Shihao Ji

Structural plasticity of the brain describes the creation of new and the deletion of old synapses over time. Rinke et al. (JPDC 2018) introduced a scalable algorithm that simulates structural plasticity for up to one billion neurons on…

分布式、并行与集群计算 · 计算机科学 2022-11-03 Fabian Czappa , Alexander Geiß , Felix Wolf

Synaptic plasticity poses itself as a powerful method of self-regulated unsupervised learning in neural networks. A recent resurgence of interest has developed in utilizing Artificial Neural Networks (ANNs) together with synaptic plasticity…

神经与进化计算 · 计算机科学 2021-11-09 Samuel Schmidgall , Joe Hays

Neural circuits exhibit remarkable computational flexibility, enabling adaptive responses to noisy and ever-changing environmental cues. A fundamental question in neuroscience concerns how a wide range of behaviors can emerge from a…

统计力学 · 物理学 2025-09-18 Giacomo Barzon , Daniel M. Busiello , Giorgio Nicoletti
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