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To build a dementia classification model for middle-aged and elderly Brazilians, implemented in Python, combining variable selection and multivariable analysis, using low-cost variables with modification potential. Observational study with…

机器学习 · 计算机科学 2026-02-20 F. S. Menezes , M. C. F. G. Barretto , E. Q. C. Garcia , T. A. E. Ferreira , J. G. Alvez

Deep neural networks (DNN) have become increasingly utilized in brain-computer interface (BCI) technologies with the outset goal of classifying human physiological signals in computer-readable format. While our present understanding of DNN…

神经与进化计算 · 计算机科学 2023-10-13 Benjamin Cichy , Jamie Lukos , Mohammad Alam , J. Cortney Bradford , Nicholas Wymbs

The diversity of cognitive deficits and neuropathological processes associated with dementias has encouraged divergence in pathophysiological explanations of disease. Here, we review an alternative framework that emphasises convergent…

神经元与认知 · 定量生物学 2020-06-12 Ece Kocagoncu , Anastasia Klimovich-Gray , Laura E Hughes , James B Rowe

There is a pressing need to automatically understand the state and progression of chronic neurological diseases such as dementia. The emergence of state-of-the-art sensing platforms offers unprecedented opportunities for indirect and…

Mild cognitive impairment (MCI) leading to dementia results in a constellation of psychiatric disorders including depression, mood disorders, schizophrenia and others. With increasing age, mild cognitive impairment leads to increased…

神经元与认知 · 定量生物学 2023-08-10 Sheng Mai

In this paper, we aimed at reviewing several different approaches present today in the search for more accurate diagnostic and treatment management in mental healthcare. Our focus is on mood disorders, and in particular on the major…

神经元与认知 · 定量生物学 2019-03-28 Milena Cukic Radenkovic

This study investigates the causal relationships between Clinical Dementia Ratings (CDR) and its six domain scores across two distinct aging datasets: the Alzheimer's Disease Neuroimaging Initiative (ADNI) and the Longitudinal Aging Study…

机器学习 · 计算机科学 2024-08-26 Wupadrasta Santosh Kumar , Sayali Rajendra Bhutare , Neelam Sinha , Thomas Gregor Issac

The ageing process may lead to cognitive and physical impairments, which may affect elderly everyday life. In recent years, the use of Brain Computer Interfaces (BCIs) based on Electroencephalography (EEG) has revealed to be particularly…

信号处理 · 电气工程与系统科学 2022-03-28 Aurora Saibene , Francesca Gasparini , Jordi Solé-Casals

Patients with semantic dementia (SD) present with remarkably consistent atrophy of neurons in the anterior temporal lobe and behavioural impairments, such as graded loss of category knowledge. While relearning of lost knowledge has been…

机器学习 · 计算机科学 2025-03-06 Devon Jarvis , Verena Klar , Richard Klein , Benjamin Rosman , Andrew Saxe

In an increasing number of neuroimaging studies, brain images, which are in the form of multidimensional arrays (tensors), have been collected on multiple subjects at multiple time points. Of scientific interest is to analyze such massive…

As other neurodegenerative diseases, Alzheimer's disease, the most frequent dementia in the elderly, is characterized by multiple progressive impairments in the brain structure and in clinical functions such as cognitive functioning and…

统计方法学 · 统计学 2019-10-21 Cécile Proust-Lima , Viviane Philipps , Jean-François Dartigues

Quantum machine learning is a new research field combining quantum information science and machine learning. Quantum computing technologies appear to be particularly well-suited for addressing problems in the health sector efficiently. They…

新兴技术 · 计算机科学 2024-12-24 Giacomo Cappiello , Filippo Caruso

\textbf{Objective:} Alzheimer's disease (AD) is the most prevalent form of dementia worldwide, encompassing a prodromal stage known as Mild Cognitive Impairment (MCI), where patients may either progress to AD or remain stable. The objective…

Neurodegenerative diseases, such as Alzheimer's or Parkinson's disease, show characteristic degradation of structural brain networks. This degradation eventually leads to changes in the network dynamics and degradation of cognitive…

适应与自组织系统 · 物理学 2020-09-21 Alain Goriely , Ellen Kuhl , Christian Bick

This paper aims to develop a new deep learning-inspired gaming approach for early detection of dementia. This research integrates a robust convolutional neural network (CNN)-based model for early dementia detection using health metrics data…

计算机视觉与模式识别 · 计算机科学 2024-12-31 Paramita Kundu Maji , Soubhik Acharya , Priti Paul , Sanjay Chakraborty , Saikat Basu

This Signal Processing Grand Challenge (SPGC) targets a difficult automatic prediction problem of societal and medical relevance, namely, the detection of Alzheimer's Dementia (AD). Participants were invited to employ signal processing and…

音频与语音处理 · 电气工程与系统科学 2023-01-16 Saturnino Luz , Fasih Haider , Davida Fromm , Ioulietta Lazarou , Ioannis Kompatsiaris , Brian MacWhinney

Over half of US adults with Alzheimer disease and related dementias remain undiagnosed, and speech-based screening offers a scalable detection approach. We compared large language model adaptation strategies for dementia detection using the…

Early detection of dementia is crucial to devise effective interventions. Comprehensive cognitive tests, while being the most accurate means of diagnosis, are long and tedious, thus limiting their applicability to a large population,…

计算机视觉与模式识别 · 计算机科学 2025-05-30 Anusha A. S. , Uma Ranjan , Medha Sharma , Siddharth Dutt

Linguistic anomalies detectable in spontaneous speech have shown promise for various clinical applications including screening for dementia and other forms of cognitive impairment. The feasibility of deploying automated tools that can…

音频与语音处理 · 电气工程与系统科学 2022-11-15 Changye Li , Trevor Cohen , Serguei Pakhomov

This paper presents our submission to the PROCESS Challenge 2025, focusing on spontaneous speech analysis for early dementia detection. For the three-class classification task (Healthy Control, Mild Cognitive Impairment, and Dementia), we…

音频与语音处理 · 电气工程与系统科学 2025-05-28 Yin-Long Liu , Yuanchao Li , Rui Feng , Liu He , Jia-Xin Chen , Yi-Ming Wang , Yu-Ang Chen , Yan-Han Peng , Jia-Hong Yuan , Zhen-Hua Ling