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The individual course of white matter fiber tracts is an important key for analysis of white matter characteristics in healthy and diseased brains. Uniquely, diffusion-weighted MRI tractography in combination with region-based or…

计算机视觉与模式识别 · 计算机科学 2018-08-21 Jakob Wasserthal , Peter Neher , Klaus H. Maier-Hein

Graph neural networks (GNNs) demonstrate a robust capability for representation learning on graphs with complex structures, showcasing superior performance in various applications. The majority of existing GNNs employ a graph convolution…

机器学习 · 计算机科学 2025-02-19 Jinlu Wang , Jipeng Guo , Yanfeng Sun , Junbin Gao , Shaofan Wang , Yachao Yang , Baocai Yin

In structure-based drug design, accurately estimating the binding affinity between a candidate ligand and its protein receptor is a central challenge. Recent advances in artificial intelligence, particularly deep learning, have demonstrated…

生物大分子 · 定量生物学 2025-09-18 Md Masud Rana , Farjana Tasnim Mukta , Duc D. Nguyen

Deep learning methods for graphs achieve remarkable performance on many node-level and graph-level prediction tasks. However, despite the proliferation of the methods and their success, prevailing Graph Neural Networks (GNNs) neglect…

机器学习 · 计算机科学 2020-11-10 Emily Alsentzer , Samuel G. Finlayson , Michelle M. Li , Marinka Zitnik

The segregation of brain fiber tractography data into distinct and anatomically meaningful clusters can help to comprehend the complex brain structure and early investigation and management of various neural disorders. We propose a novel…

计算机视觉与模式识别 · 计算机科学 2017-10-17 Tushar Gupta , Shreyas Malakarjun Patil , Mukkaram Tailor , Daksh Thapar , Aditya Nigam

Current theories hold that brain function is highly related to long-range physical connections through axonal bundles, namely extrinsic connectiv-ity. However, obtaining a groupwise cortical parcellation based on extrinsic connectivity…

应用统计 · 统计学 2017-01-06 Guillermo Gallardo , William Wells , Rachid Deriche , Demian Wassermann

This work presents BundleSeg, a reliable, reproducible, and fast method for extracting white matter pathways. The proposed method combines an iterative registration procedure with a recently developed precise streamline search algorithm…

图像与视频处理 · 电气工程与系统科学 2023-08-23 Etienne St-Onge , Kurt G Schilling , Francois Rheault

Motion artifacts caused by prolonged acquisition time are a significant challenge in Magnetic Resonance Imaging (MRI), hindering accurate tissue segmentation. These artifacts appear as blurred images that mimic tissue-like appearances,…

图像与视频处理 · 电气工程与系统科学 2024-12-06 Sunyoung Jung , Yoonseok Choi , Mohammed A. Al-masni , Minyoung Jung , Dong-Hyun Kim

In this paper, we propose a deep learning approach for image registration by predicting deformation from image appearance. Since obtaining ground-truth deformation fields for training can be challenging, we design a fully convolutional…

计算机视觉与模式识别 · 计算机科学 2018-02-14 Jingfan Fan , Xiaohuan Cao , Pew-Thian Yap , Dinggang Shen

In studying structural inter-connections in the human brain, it is common to first estimate fiber bundles connecting different regions of the brain relying on diffusion MRI. These fiber bundles act as highways for neural activity and…

应用统计 · 统计学 2016-12-06 Zhengwu Zhang , Maxime Descoteaux , David B. Dunson

Most previous bounding-box-based segmentation methods assume the bounding box tightly covers the object of interest. However it is common that a rectangle input could be too large or too small. In this paper, we propose a novel segmentation…

计算机视觉与模式识别 · 计算机科学 2017-07-18 Ning Xu , Brian Price , Scott Cohen , Jimei Yang , Thomas Huang

Neuroscientists have devoted significant effort into the creation of standard brain reference atlases for high-throughput registration of anatomical regions of interest. However, variability in brain size and form across individuals poses a…

计算机视觉与模式识别 · 计算机科学 2019-06-10 Asim Iqbal , Romesa Khan , Theofanis Karayannis

Brains with complex distortion of cerebral anatomy present several challenges to automatic tissue segmentation methods of T1-weighted MR images. First, the very high variability in the morphology of the tissues can be incompatible with the…

A connectional brain template (CBT) is a normalized graph-based representation of a population of brain networks also regarded as an average connectome. CBTs are powerful tools for creating representative maps of brain connectivity in…

计算机视觉与模式识别 · 计算机科学 2020-12-29 Mustafa Burak Gurbuz , Islem Rekik

Streamline classification is essential to identify anatomically meaningful white matter tracts from diffusion MRI (dMRI) tractography. However, current streamline classification methods rely primarily on the geometric features of the…

计算机视觉与模式识别 · 计算机科学 2025-11-25 Haotian Yan , Bocheng Guo , Jianzhong He , Nir A. Sochen , Ofer Pasternak , Lauren J O'Donnell , Fan Zhang

Automatic segmentation of neuronal topology is critical for handling large scale neuroimaging data, as it can greatly accelerate neuron annotation and analysis. However, the intricate morphology of neuronal branches and the occlusions among…

图像与视频处理 · 电气工程与系统科学 2025-08-01 Huayu Fu , Jiamin Li , Haozhi Qu , Xiaolin Hu , Zengcai Guo

An essential premise for neuroscience brain network analysis is the successful segmentation of the cerebral cortex into functionally homogeneous regions. Resting-state functional magnetic resonance imaging (rs-fMRI), capturing the…

神经元与认知 · 定量生物学 2023-09-20 Xiaoxiao Ma , Chunzhi Yi , Zhicai Zhong , Hui Zhou , Baichun Wei , Haiqi Zhu , Feng Jiang

Embedding real-world networks presents challenges because it is not clear how to identify their latent geometries. Embedding some disassortative networks, such as scale-free networks, to the Euclidean space has been shown to incur…

机器学习 · 计算机科学 2021-12-07 Zheng Xie , Xiaojing Zuo , Yiping Song

Data-driven brain parcellations aim to provide a more accurate representation of an individual's functional connectivity, since they are able to capture individual variability that arises due to development or disease. This renders…

神经元与认知 · 定量生物学 2017-03-30 Sofia Ira Ktena , Salim Arslan , Sarah Parisot , Daniel Rueckert

Fully automatic cardiac segmentation can be a fast and reproducible method to extract clinical measurements from an echocardiography examination. The U-Net architecture is the current state-of-the-art deep learning architecture for medical…

图像与视频处理 · 电气工程与系统科学 2024-10-28 Gilles Van De Vyver , Sarina Thomas , Guy Ben-Yosef , Sindre Hellum Olaisen , Håvard Dalen , Lasse Løvstakken , Erik Smistad