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Opioids are the preferred medications for the treatment of pain in the intensive care unit. While undertreatment leads to unrelieved pain and poor clinical outcomes, excessive use of opioids puts patients at risk of experiencing multiple…

机器学习 · 计算机科学 2019-04-26 Daniel Lopez-Martinez , Patrick Eschenfeldt , Sassan Ostvar , Myles Ingram , Chin Hur , Rosalind Picard

Online matching problems arise in many complex systems, from cloud services and online marketplaces to organ exchange networks, where timely, principled decisions are critical for maintaining high system performance. Traditional heuristics…

机器学习 · 统计学 2025-10-09 Chiara Mignacco , Matthieu Jonckheere , Gilles Stoltz

As critically ill patients frequently develop anemia or coagulopathy, transfusion of blood products is a frequent intervention in the Intensive Care Units (ICU). However, inappropriate transfusion decisions made by physicians are often…

机器学习 · 计算机科学 2022-06-30 Yuqing Wang , Yun Zhao , Linda Petzold

In kidney exchange programmes (KEP) patients may swap their incompatible donors leading to cycles of kidney transplants. Nowadays, countries try to merge their national patient-donor pools leading to international KEPs (IKEPs). As shown in…

计算机科学与博弈论 · 计算机科学 2025-12-30 Márton Benedek , Péter Biró , Gergely Csáji , Matthew Johnson , Daniël Paulusma , Xin Ye

In this paper, we propose a reinforcement learning-based algorithm for trajectory optimization for constrained dynamical systems. This problem is motivated by the fact that for most robotic systems, the dynamics may not always be known.…

Understanding the transition events between metastable states in complex systems is an important subject in the fields of computational physics, chemistry and biology. The transition pathway plays an important role in characterizing the…

计算物理 · 物理学 2024-04-10 Bo Lin , Yangzheng Zhong , Weiqing Ren

Combating an epidemic entails finding a plan that describes when and how to apply different interventions, such as mask-wearing mandates, vaccinations, school or workplace closures. An optimal plan will curb an epidemic with minimal loss of…

机器学习 · 计算机科学 2023-06-08 Anh Mai , Nikunj Gupta , Azza Abouzied , Dennis Shasha

Kidney transplantation is the best treatment for end-stage renal failure patients. The predominant method used for kidney quality assessment is the Cox regression-based, kidney donor risk index. A machine learning method may provide…

机器学习 · 计算机科学 2020-12-08 Eric S. Pahl , W. Nick Street , Hans J. Johnson , Alan I. Reed

In this paper, we present a comprehensive, in-depth survey of the literature on reinforcement learning approaches to decision optimization problems in a typical ridesharing system. Papers on the topics of rideshare matching, vehicle…

机器学习 · 计算机科学 2022-10-25 Zhiwei Qin , Hongtu Zhu , Jieping Ye

Sepsis is a leading cause of death in the ICU. It is a disease requiring complex interventions in a short period of time, but its optimal treatment strategy remains uncertain. Evidence suggests that the practices of currently used treatment…

机器学习 · 计算机科学 2022-07-15 Zeyu Wang , Huiying Zhao , Peng Ren , Yuxi Zhou , Ming Sheng

Current methods for end-to-end constructive neural combinatorial optimization usually train a policy using behavior cloning from expert solutions or policy gradient methods from reinforcement learning. While behavior cloning is…

机器学习 · 计算机科学 2024-11-05 Jonathan Pirnay , Dominik G. Grimm

Many current behavior generation methods struggle to handle real-world traffic situations as they do not scale well with complexity. However, behaviors can be learned off-line using data-driven approaches. Especially, reinforcement learning…

机器学习 · 计算机科学 2020-06-02 Patrick Hart , Leonard Rychly , Alois Knol

We design a new iterative algorithm, called REINFORCE-OPT, for solving a general type of optimization problems. This algorithm parameterizes the solution search rule and iteratively updates the parameter using a reinforcement learning (RL)…

最优化与控制 · 数学 2025-01-27 Chen Xu , Yun-Bin Zhao , Zhipeng Lu , Ye Zhang

Referral workflow inefficiencies, including misaligned referrals and delays, contribute to suboptimal patient outcomes and higher healthcare costs. In this study, we investigated the possibility of predicting procedural needs based on…

Medical treatments often involve a sequence of decisions, each informed by previous outcomes. This process closely aligns with reinforcement learning (RL), a framework for optimizing sequential decisions to maximize cumulative rewards under…

机器学习 · 计算机科学 2024-10-15 Ali Shirali , Alexander Schubert , Ahmed Alaa

Knee osteoarthritis (KOA) is among the musculoskeletal disorders that considerably restrict joint mobility, cause severe chronic pain and impact negatively on quality life. It is one of the persistent health issues worldwide. Generally,…

人工智能 · 计算机科学 2026-05-08 Dayam Nadeem , Neha , Safdar Mustafa , Adnan Alvi , Mohd Hussain

Knee osteoarthritis (OA) is one of the most widespread and burdensome health problems [1-4]. Total knee replacement (TKR) may be offered as treatment for end-stage knee OA. Nevertheless, TKR is an invasive procedure involving prosthesis…

图像与视频处理 · 电气工程与系统科学 2025-11-20 Zhisen Hu , Dominic Cullen , David S. Johnson , Aleksei Tiulpin , Timothy F. Cootes , Claudia Lindner

Offline policy learning is aimed at learning decision-making policies using existing datasets of trajectories without collecting additional data. The primary motivation for using reinforcement learning (RL) instead of supervised learning…

While reinforcement learning (RL) holds great potential for decision making in the real world, it suffers from a number of unique difficulties which often need specific consideration. In particular: it is highly non-stationary; suffers from…

Lane-change maneuvers are commonly executed by drivers to follow a certain routing plan, overtake a slower vehicle, adapt to a merging lane ahead, etc. However, improper lane change behaviors can be a major cause of traffic flow disruptions…

机器学习 · 计算机科学 2020-05-22 Fei Ye , Xuxin Cheng , Pin Wang , Ching-Yao Chan , Jiucai Zhang