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Deep neural networks have led to state-of-the-art results in many medical imaging tasks including Alzheimer's disease (AD) detection based on structural magnetic resonance imaging (MRI) data. However, the network decisions are often…

定量方法 · 定量生物学 2019-08-28 Moritz Böhle , Fabian Eitel , Martin Weygandt , Kerstin Ritter

The use of convolutional neural networks (CNNs) for classification tasks has become dominant in various medical imaging applications. At the same time, recent advances in interpretable machine learning techniques have shown great potential…

图像与视频处理 · 电气工程与系统科学 2019-10-02 Irina Grigorescu , Lucilio Cordero-Grande , A David Edwards , Jo Hajnal , Marc Modat , Maria Deprez

Multiple Sclerosis (MS) is an autoimmune disease that leads to lesions in the central nervous system. Magnetic resonance (MR) images provide sufficient imaging contrast to visualize and detect lesions, particularly those in the white…

计算机视觉与模式识别 · 计算机科学 2018-03-28 Snehashis Roy , John A. Butman , Daniel S. Reich , Peter A. Calabresi , Dzung L. Pham

Convolutional Neural Networks (CNN) have become state-of-the-art in the field of image classification. However, not everything is understood about their inner representations. This paper tackles the interpretability and explainability of…

计算机视觉与模式识别 · 计算机科学 2019-11-11 Brian Kenji Iwana , Ryohei Kuroki , Seiichi Uchida

Interpreting complex neural networks is crucial for understanding their decision-making processes, particularly in applications where transparency and accountability are essential. This proposed method addresses this need by focusing on…

神经与进化计算 · 计算机科学 2024-12-10 Deepshikha Bhati , Fnu Neha , Md Amiruzzaman , Angela Guercio , Deepak Kumar Shukla , Ben Ward

Despite the tremendous achievements of deep convolutional neural networks (CNNs) in many computer vision tasks, understanding how they actually work remains a significant challenge. In this paper, we propose a novel two-step understanding…

计算机视觉与模式识别 · 计算机科学 2019-04-02 Heyi Li , Yunke Tian , Klaus Mueller , Xin Chen

In recent years, artificial intelligence (AI) systems have come to the forefront. These systems, mostly based on Deep learning (DL), achieve excellent results in areas such as image processing, natural language processing, or speech…

计算机视觉与模式识别 · 计算机科学 2023-04-18 Frantisek Sefcik , Wanda Benesova

Visualizing and interpreting convolutional neural networks (CNNs) is an important task to increase trust in automatic medical decision making systems. In this study, we train a 3D CNN to detect Alzheimer's disease based on structural MRI…

计算机视觉与模式识别 · 计算机科学 2018-12-07 Johannes Rieke , Fabian Eitel , Martin Weygandt , John-Dylan Haynes , Kerstin Ritter

Layer-wise relevance propagation (LRP) is a recently proposed technique for explaining predictions of complex non-linear classifiers in terms of input variables. In this paper, we apply LRP for the first time to natural language processing…

计算与语言 · 计算机科学 2016-06-24 Leila Arras , Franziska Horn , Grégoire Montavon , Klaus-Robert Müller , Wojciech Samek

Segmentation of white matter lesions and deep grey matter structures is an important task in the quantification of magnetic resonance imaging in multiple sclerosis. In this paper we explore segmentation solutions based on convolutional…

A number of backpropagation-based approaches such as DeConvNets, vanilla Gradient Visualization and Guided Backpropagation have been proposed to better understand individual decisions of deep convolutional neural networks. The saliency maps…

计算机视觉与模式识别 · 计算机科学 2019-09-04 Jindong Gu , Yinchong Yang , Volker Tresp

Background and Aim: Accurate classification of Magnetic Resonance Images (MRI) is essential to accurately predict Mild Cognitive Impairment (MCI) to Alzheimer's Disease (AD) conversion. Meanwhile, deep learning has been successfully…

计算机视觉与模式识别 · 计算机科学 2021-09-03 Kshitiz Shrestha , Omar Hisham Alsadoon , Abeer Alsadoon , Tarik A. Rashid , Rasha S. Ali , P. W. C. Prasad , Oday D. Jerew

Alzheimer's disease is a progressive neurodegenerative disorder that gradually deprives the patient of cognitive function and can end in death. With the advancement of technology today, it is possible to detect Alzheimer's disease through…

图像与视频处理 · 电气工程与系统科学 2022-07-05 Muhammad Wildan Oktavian , Novanto Yudistira , Achmad Ridok

Dense prediction is a fundamental requirement for many medical vision tasks such as medical image restoration, registration, and segmentation. The most popular vision model, Convolutional Neural Networks (CNNs), has reached bottlenecks due…

图像与视频处理 · 电气工程与系统科学 2023-11-29 Mingyuan Meng , Yuxin Xue , Dagan Feng , Lei Bi , Jinman Kim

Convolutional neural networks (CNNs) underpin many modern computer vision systems. With applications ranging from common to critical areas, a need to explain and understand the model and its decisions (XAI) emerged. Prior works suggest that…

计算机视觉与模式识别 · 计算机科学 2025-11-05 Vojtěch Kůr , Adam Bajger , Adam Kukučka , Marek Hradil , Vít Musil , Tomáš Brázdil

Multiple Sclerosis (MS) is a type of brain disease which causes visual, sensory, and motor problems for people with a detrimental effect on the functioning of the nervous system. In order to diagnose MS, multiple screening methods have been…

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…

Multiple sclerosis is an inflammatory autoimmune demyelinating disease that is characterized by lesions in the central nervous system. Typically, magnetic resonance imaging (MRI) is used for tracking disease progression. Automatic image…

图像与视频处理 · 电气工程与系统科学 2020-08-06 Nils Gessert , Julia Krüger , Roland Opfer , Ann-Christin Ostwaldt , Praveena Manogaran , Hagen H. Kitzler , Sven Schippling , Alexander Schlaefer

In this paper, we present an automated approach for segmenting multiple sclerosis (MS) lesions from multi-modal brain magnetic resonance images. Our method is based on a deep end-to-end 2D convolutional neural network (CNN) for slice-based…

计算机视觉与模式识别 · 计算机科学 2019-04-09 Shahab Aslani , Michael Dayan , Loredana Storelli , Massimo Filippi , Vittorio Murino , Maria A Rocca , Diego Sona

Lyme disease which is one of the most common infectious vector-borne diseases manifests itself in most cases with erythema migrans (EM) skin lesions. Recent studies show that convolutional neural networks (CNNs) perform well to identify…

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