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Deep learning based models, generally, require a large number of samples for appropriate training, a requirement that is difficult to satisfy in the medical field. This issue can usually be avoided with a proper initialization of the…

计算机视觉与模式识别 · 计算机科学 2019-06-19 Taibou Birgui Sekou , Moncef Hidane , Julien Olivier , Hubert Cardot

In multicenter biomedical research, integrating data from multiple decentralized sites provides more robust and generalizable findings due to its larger sample size and the ability to account for the between-site heterogeneity. However,…

统计方法学 · 统计学 2025-12-29 Xiaokang Liu , Yuchen Yang , Yifei Sun , Jiang Bian , Yanyuan Ma , Raymond J. Carroll , Yong Chen

$\bf{Purpose:}$ The goal of this study was (i) to use artificial intelligence to automate the traditionally labor-intensive process of manual segmentation of tumor regions in pathology slides performed by a pathologist and (ii) to validate…

There has recently been great progress in automatic segmentation of medical images with deep learning algorithms. In most works observer variation is acknowledged to be a problem as it makes training data heterogeneous but so far no…

计算机视觉与模式识别 · 计算机科学 2020-01-24 Arkadiy Dushatskiy , Adriënne M. Mendrik , Peter A. N. Bosman , Tanja Alderliesten

Deep learning algorithms have become the golden standard for segmentation of medical imaging data. In most works, the variability and heterogeneity of real clinical data is acknowledged to still be a problem. One way to automatically…

图像与视频处理 · 电气工程与系统科学 2022-02-25 Arkadiy Dushatskiy , Gerry Lowe , Peter A. N. Bosman , Tanja Alderliesten

At this moment, databanks worldwide contain brain images of previously unimaginable numbers. Combined with developments in data science, these massive data provide the potential to better understand the genetic underpinnings of brain…

机器学习 · 统计学 2025-01-30 Santiago Silva , Boris Gutman , Eduardo Romero , Paul M Thompson , Andre Altmann , Marco Lorenzi

Widely used traditional supervised deep learning methods require a large number of training samples but often fail to generalize on unseen datasets. Therefore, a more general application of any trained model is quite limited for medical…

计算机视觉与模式识别 · 计算机科学 2022-02-01 Rabindra Khadga , Debesh Jha , Steven Hicks , Vajira Thambawita , Michael A. Riegler , Sharib Ali , Pål Halvorsen

Most research on novel techniques for 3D Medical Image Segmentation (MIS) is currently done using Deep Learning with GPU accelerators. The principal challenge of such technique is that a single input can easily cope computing resources, and…

机器学习 · 计算机科学 2021-11-01 Josep Lluis Berral , Oriol Aranda , Juan Luis Dominguez , Jordi Torres

Collaborative training across multiple institutions is becoming essential for building reliable medical image segmentation models. However, privacy regulations, data silos, and uneven data availability prevent hospitals from sharing raw…

定量方法 · 定量生物学 2026-03-09 Saheed Ademola Bello , Muhammad Shahid Jabbar , Muhammad Sohail Ibrahim , Shujaat Khan

Many recent medical segmentation systems rely on powerful deep learning models to solve highly specific tasks. To maximize performance, it is standard practice to evaluate numerous pipelines with varying model topologies, optimization…

机器学习 · 计算机科学 2019-11-06 Mathias Perslev , Erik Bjørnager Dam , Akshay Pai , Christian Igel

Background. Subdural hematoma (SDH) is a common neurosurgical emergency, with increasing incidence in aging populations. Rapid and accurate identification is essential to guide timely intervention, yet existing automated tools focus…

计算机视觉与模式识别 · 计算机科学 2025-12-11 Vasiliki Stoumpou , Rohan Kumar , Bernard Burman , Diego Ojeda , Tapan Mehta , Dimitris Bertsimas

The segmentation of lesions in Moderate to Severe Traumatic Brain Injury (msTBI) presents a significant challenge in neuroimaging due to the diverse characteristics of these lesions, which vary in size, shape, and distribution across brain…

计算机视觉与模式识别 · 计算机科学 2025-04-10 Constantin Ulrich , Tassilo Wald , Fabian Isensee , Klaus H. Maier-Hein

The performance of deep neural networks typically increases with the number of training images. However, not all images have the same importance towards improved performance and robustness. In fetal brain MRI, abnormalities exacerbate the…

Melanoma brain metastases (MBM) are common and spatially heterogeneous lesions, complicating cohort-level analyses due to anatomical variability and differing MRI protocols. We propose a fully differentiable, deep-learning-based deformable…

计算机视觉与模式识别 · 计算机科学 2026-02-16 Nanna E. Wielenberg , Ilinca Popp , Oliver Blanck , Lucas Zander , Jan C. Peeken , Stephanie E. Combs , Anca-Ligia Grosu , Dimos Baltas , Tobias Fechter

Magnetic resonance imaging (MRI) is critically important for brain mapping in both scientific research and clinical studies. Precise segmentation of brain tumors facilitates clinical diagnosis, evaluations, and surgical planning. Deep…

图像与视频处理 · 电气工程与系统科学 2023-05-01 Rui Nian , Guoyao Zhang , Yao Sui , Yuqi Qian , Qiuying Li , Mingzhang Zhao , Jianhui Li , Ali Gholipour , Simon K. Warfield

The complex heterogeneity of brain tumours is increasingly recognized to demand data of magnitudes and richness only fully-inclusive, large-scale collections drawn from routine clinical care could plausibly offer. This is a task…

计算机视觉与模式识别 · 计算机科学 2023-05-01 James K Ruffle , Samia Mohinta , Robert J Gray , Harpreet Hyare , Parashkev Nachev

Automated prostate segmentation in MRI is highly demanded for computer-assisted diagnosis. Recently, a variety of deep learning methods have achieved remarkable progress in this task, usually relying on large amounts of training data. Due…

图像与视频处理 · 电气工程与系统科学 2020-02-20 Quande Liu , Qi Dou , Lequan Yu , Pheng Ann Heng

Segmenting a structural magnetic resonance imaging (MRI) scan is an important pre-processing step for analytic procedures and subsequent inferences about longitudinal tissue changes. Manual segmentation defines the current gold standard in…

计算机视觉与模式识别 · 计算机科学 2017-06-07 Alex Fedorov , Jeremy Johnson , Eswar Damaraju , Alexei Ozerin , Vince Calhoun , Sergey Plis

Brain imaging data are important in brain sciences yet expensive to obtain, with big volume (i.e., large p) but small sample size (i.e., small n). To tackle this problem, transfer learning is a promising direction that leverages source data…

机器学习 · 计算机科学 2025-09-22 Shuo Zhou , Wenwen Li , Christopher R. Cox , Haiping Lu

Existing image segmentation networks mainly leverage large-scale labeled datasets to attain high accuracy. However, labeling medical images is very expensive since it requires sophisticated expert knowledge. Thus, it is more desirable to…

图像与视频处理 · 电气工程与系统科学 2021-02-04 Yuhang Ding , Xin Yu , Yi Yang