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The introduction of non-native organisms into complex microbiome communities holds enormous potential to benefit society. However, microbiome engineering faces several challenges including successful establishment of the organism into the…

The built environment provides an excellent setting for interdisciplinary research on the dynamics of microbial communities. The system is simplified compared to many natural settings, and to some extent the entire environment can be…

The intestinal microbiota plays important roles in digestion and resistance against entero-pathogens. As with other ecosystems, its species composition is resilient against small disturbances but strong perturbations such as antibiotics can…

定量方法 · 定量生物学 2015-06-04 Vanni Bucci , Serena Bradde , Giulio Biroli , Joao B. Xavier

Linear waste management systems are unsustainable and contribute to environmental degradation, economic inequity, and health disparities. Among the array of environmental challenges stemming from anthropogenic impacts, the management of…

定量方法 · 定量生物学 2024-09-12 Jeff Meilander , J. Gregory Caporaso

A fundamental goal of microbial ecology is to understand what determines the diversity, stability, and structure of microbial ecosystems. The microbial context poses special conceptual challenges because of the strong mutual influences…

生物物理 · 物理学 2019-03-06 Robert Marsland , Wenping Cui , Joshua Goldford , Alvaro Sanchez , Kirill Korolev , Pankaj Mehta

Microbiomes, which are collections of interacting microbes in an environment, often substantially impact the environmental patches or living hosts that they occupy. In microbiome models, it is important to consider both the local dynamics…

动力系统 · 数学 2025-07-18 Michael Johnson , Mason A. Porter

Microbial communities assemble through a complex set of interactions between microbes and their environment, and the resulting metabolic impact on the host ecosystem can be profound. Microbial activity is known to impact human health, plant…

定量方法 · 定量生物学 2023-11-09 James D. Brunner , Laverne A. Gallegos-Graves , Marie E. Kroeger

Microbes can affect processes from food production to human health. Such microbes are not isolated, but rather interact with each other and establish connections with their living environments. Understanding these interactions is essential…

应用统计 · 统计学 2021-09-07 Liang Chen , Qiuyan He , Hui Wan , Shun He , Minghua Deng

Recent work suggests that cross-feeding -- the secretion and consumption of metabolic biproducts by microbes -- is essential for understanding microbial ecology. Yet how cross-feeding and competition combine to give rise to ecosystem-level…

种群与进化 · 定量生物学 2021-10-12 Pankaj Mehta , Robert Marsland

The intricate interplay between host organisms and their gut microbiota has catalyzed research into the microbiome's role in disease, shedding light on novel aspects of disease pathogenesis. However, the mechanisms through which the…

统计方法学 · 统计学 2024-02-20 Lei Fang , Yue Wang , Chenglong Ye

Bioconvection, a phenomenon arising from the collective motion of motile microorganisms, plays a crucial role in shaping microbial distributions, fluid dynamics, and bloom formation in aquatic environments. While extensive research has…

生物物理 · 物理学 2025-04-15 Samarendu Biswas , Sachidananda Mahato , Jayabrata Dhar

The preservation of soil health is a critical challenge in the 21st century due to its significant impact on agriculture, human health, and biodiversity. We provide the first deep investigation of the predictive potential of machine…

机器学习 · 统计学 2024-02-20 Rosa Aghdam , Xudong Tang , Shan Shan , Richard Lankau , Claudia Solís-Lemus

The microbiome constitutes a complex microbial ecology of interacting components that regulates important pathways in the host. Measurements of microbial abundances are key to learning the intricate network of interactions amongst microbes.…

统计方法学 · 统计学 2024-06-17 Veronica Vinciotti , Ernst Wit , Francisco Richter

In ecological systems heterogeneous interactions between pathogens take place simultaneously. This occurs, for instance, when two pathogens cooperate, while at the same time multiple strains of these pathogens co-circulate and compete.…

种群与进化 · 定量生物学 2025-05-05 Francesco Pinotti , Fakhteh Ghanbarnejad , Philipp Hövel , Chiara Poletto

Social interaction between microbes can be described at many levels of details, ranging from the biochemistry of cell-cell interactions to the ecological dynamics of populations. Choosing the best level to model microbial communities…

种群与进化 · 定量生物学 2020-09-09 Chen Liao , Tong Wang , Sergei Maslov , Joao B. Xavier

The explosion in known microbial diversity in the last two decades has made it abundantly clear that microbes in the environment do not exist in isolation; they are members of communities. Accordingly, omics approaches such as metagenomics…

定量方法 · 定量生物学 2024-07-15 James C. Kosmopoulos , Karthik Anantharaman

The human microbiome is the ensemble of genes in the microbes that live inside and on the surface of humans. Because microbial sequencing information is now much easier to come by than phenotypic information, there has been an explosion of…

种群与进化 · 定量生物学 2014-07-08 Frederick A Matsen

Microbes thrive in diverse porous environments -- from soil and riverbeds to human lungs and cancer tissues -- spanning multiple scales and conditions. Short- to long-term fluctuations in local factors induce spatio-temporal…

生物物理 · 物理学 2024-04-22 Chenyu Jin , Anupam Sengupta

The gut microbiome plays a crucial role in human health, yet the mechanisms underlying host-microbiome interactions remain unclear, limiting its translational potential. Recent microbiome multiomics studies, particularly paired…

统计方法学 · 统计学 2025-04-09 Haoran Shi , Yue Wang , Dan Cheng

Bacterial communities such as biofilms are widely recognised as being important for survival and persistence of bacteria in harsh environments. Mechanistic models of biofilm growth indicate that the way in which the surface is seeded can…

定量方法 · 定量生物学 2007-05-23 Leah R. Johnson
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