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Glioblastoma is among the most aggressive brain tumors in adults, characterized by patient-specific invasion patterns driven by the underlying brain microstructure. In this work, we present a proof-of-concept for a mathematical model of GBL…

图像与视频处理 · 电气工程与系统科学 2025-06-23 D. Cerrone , D. Riccobelli , S. Gazzoni , P. Vitullo , F. Ballarin , J. Falco , F. Acerbi , A. Manzoni , P. Zunino , P. Ciarletta

With the rapid development of artificial intelligence (AI), AI-assisted medical imaging analysis demonstrates remarkable performance in early lung cancer screening. However, the costly annotation process and privacy concerns limit the…

图像与视频处理 · 电气工程与系统科学 2025-08-14 Yifan Jiang , Yannick Lemaréchal , Sophie Plante , Josée Bafaro , Jessica Abi-Rjeile , Philippe Joubert , Philippe Després , Venkata Manem

Deriving interpretable prognostic features from deep-learning-based prognostic histopathology models remains a challenge. In this study, we developed a deep learning system (DLS) for predicting disease specific survival for stage II and III…

Tumor-stroma ratio (TSR) is a prognostic factor for many types of solid tumors. In this study, we propose a method for automated estimation of TSR from histopathological images of colorectal cancer. The method is based on convolutional…

计算机视觉与模式识别 · 计算机科学 2023-06-07 Liisa Petäinen , Juha P. Väyrynen , Pekka Ruusuvuori , Ilkka Pölönen , Sami Äyrämö , Teijo Kuopio

We address the problem of supporting radiologists in the longitudinal management of lung cancer. Therefore, we proposed a deep learning pipeline, composed of four stages that completely automatized from the detection of nodules to the…

图像与视频处理 · 电气工程与系统科学 2021-03-29 Xavier Rafael-Palou , Anton Aubanell , Mario Ceresa , Vicent Ribas , Gemma Piella , Miguel A. González Ballester

The application of Deep Learning (DL) for medical diagnosis is often hampered by two problems. First, the amount of training data may be scarce, as it is limited by the number of patients who have acquired the condition to be diagnosed.…

计算机视觉与模式识别 · 计算机科学 2020-07-17 Diyuan Lu , Nenad Polomac , Iskra Gacheva , Elke Hattingen , Jochen Triesch

Glioma, an aggressive brain malignancy characterized by rapid progression and its poor prognosis, poses significant challenges for accurate evolution prediction. These challenges are exacerbated by sparse, irregularly acquired longitudinal…

计算机视觉与模式识别 · 计算机科学 2025-09-16 Aghiles Kebaili , Romain Modzelewski , Jérôme Lapuyade-Lahorgue , Maxime Fontanilles , Sébastien Thureau , Su Ruan

Background: Voxel-based analysis (VBA) for population level radiotherapy (RT) outcomes modeling requires topology preserving inter-patient deformable image registration (DIR) that preserves tumors on moving images while avoiding unrealistic…

图像与视频处理 · 电气工程与系统科学 2024-11-28 Jue Jiang , Chloe Min Seo Choi , Maria Thor , Joseph O. Deasy , Harini Veeraraghavan

In this paper, we present a fully automatic brain tumor segmentation method based on Deep Neural Networks (DNNs). The proposed networks are tailored to glioblastomas (both low and high grade) pictured in MR images. By their very nature,…

计算机视觉与模式识别 · 计算机科学 2016-05-23 Mohammad Havaei , Axel Davy , David Warde-Farley , Antoine Biard , Aaron Courville , Yoshua Bengio , Chris Pal , Pierre-Marc Jodoin , Hugo Larochelle

Percolation theory from statistical physics has been applied to several aspects of tumor progression. Tumor growth on percolation clusters has been used to model spatial expansion, vascular percolation to describe nutrient supply and…

其他定量生物学 · 定量生物学 2026-05-04 Arturo Tozzi

Glioblastoma exhibits diverse, infiltrative, and patient-specific growth patterns that are only partially visible on routine MRI, making it difficult to reliably assess true tumor extent and personalize treatment planning and follow-up. We…

计算机视觉与模式识别 · 计算机科学 2026-03-06 Valentin Biller , Niklas Bubeck , Lucas Zimmer , Ayhan Can Erdur , Sandeep Nagar , Anke Meyer-Baese , Daniel Rückert , Benedikt Wiestler , Jonas Weidner

Image pre-training, the current de-facto paradigm for a wide range of visual tasks, is generally less favored in the field of video recognition. By contrast, a common strategy is to directly train with spatiotemporal convolutional neural…

计算机视觉与模式识别 · 计算机科学 2022-08-03 Xianhang Li , Huiyu Wang , Chen Wei , Jieru Mei , Alan Yuille , Yuyin Zhou , Cihang Xie

Breast cancer remains the most commonly diagnosed malignancy among women in the developed world. Early detection through mammography screening plays a pivotal role in reducing mortality rates. While computer-aided diagnosis (CAD) systems…

计算机视觉与模式识别 · 计算机科学 2025-10-30 Shunjie-Fabian Zheng , Hyeonjun Lee , Thijs Kooi , Ali Diba

In this study, an automated three dimensional (3D) deep segmentation approach for detecting gliomas in 3D pre-operative MRI scans is proposed. Then, a classi-fication algorithm based on random forests, for survival prediction is presented.…

图像与视频处理 · 电气工程与系统科学 2019-11-20 Mehdi Amian , Mohammadreza Soltaninejad

Predicting future states of dynamic agents is a fundamental task in autonomous driving. An expressive representation for this purpose is Occupancy Flow Fields, which provide a scalable and unified format for modeling motion, spatial extent,…

计算机视觉与模式识别 · 计算机科学 2025-06-09 Peter Lengyel

With COVID-19 affecting every country globally and changing everyday life, the ability to forecast the spread of the disease is more important than any previous epidemic. The conventional methods of disease-spread modeling, compartmental…

机器学习 · 统计学 2022-08-19 Benjamin Lucas , Behzad Vahedi , Morteza Karimzadeh

Automation of brain tumor segmentation in 3D magnetic resonance images (MRIs) is key to assess the diagnostic and treatment of the disease. In recent years, convolutional neural networks (CNNs) have shown improved results in the task.…

图像与视频处理 · 电气工程与系统科学 2021-01-01 Laura Mora Ballestar , Veronica Vilaplana

The spatial distributions of different types of cells could reveal a cancer cell growth pattern, its relationships with the tumor microenvironment and the immune response of the body, all of which represent key hallmarks of cancer. However,…

计算机视觉与模式识别 · 计算机科学 2018-09-28 Shidan Wang , Tao Wang , Lin Yang , Faliu Yi , Xin Luo , Yikun Yang , Adi Gazdar , Junya Fujimoto , Ignacio I. Wistuba , Bo Yao , ShinYi Lin , Yang Xie , Yousheng Mao , Guanghua Xiao

Precise automated delineation of post-operative gross tumor volume in glioblastoma cases is challenging and time-consuming owing to the presence of edema and the deformed brain tissue resulting from the surgical tumor resection. To develop…

Determining the spread of GTV$_{LN}$ is essential in defining the respective resection or irradiating regions for the downstream workflows of surgical resection and radiotherapy for many cancers. Different from the more common enlarged…

计算机视觉与模式识别 · 计算机科学 2020-09-01 Chun-Hung Chao , Zhuotun Zhu , Dazhou Guo , Ke Yan , Tsung-Ying Ho , Jinzheng Cai , Adam P. Harrison , Xianghua Ye , Jing Xiao , Alan Yuille , Min Sun , Le Lu , Dakai Jin