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Diabetic retinopathy (DR) is a leading cause of vision loss, requiring early and accurate assessment to prevent irreversible damage. Spectral Domain Optical Coherence Tomography (SD-OCT) enables high-resolution retinal imaging, but…

图像与视频处理 · 电气工程与系统科学 2025-07-15 S. Chen , D. Ma , M. Raviselvan , S. Sundaramoorthy , K. Popuri , M. J. Ju , M. V. Sarunic , D. Ratra , M. F. Beg

We present OCTCube-M, a 3D OCT-based multi-modal foundation model for jointly analyzing OCT and en face images. OCTCube-M first developed OCTCube, a 3D foundation model pre-trained on 26,685 3D OCT volumes encompassing 1.62 million 2D OCT…

图像与视频处理 · 电气工程与系统科学 2024-12-20 Zixuan Liu , Hanwen Xu , Addie Woicik , Linda G. Shapiro , Marian Blazes , Yue Wu , Verena Steffen , Catherine Cukras , Cecilia S. Lee , Miao Zhang , Aaron Y. Lee , Sheng Wang

The development of artificial intelligence models for macular edema (ME) analy-sis always relies on expert-annotated pixel-level image datasets which are expen-sive to collect prospectively. While anomaly-detection-based weakly-supervised…

图像与视频处理 · 电气工程与系统科学 2025-08-27 Yuhui Tao , Yizhe Zhang , Qiang Chen

Purpose: To evaluate Pegasus-OCT, a clinical decision support software for the identification of features of retinal disease from macula OCT scans, across heterogenous populations involving varying patient demographics, device…

图像与视频处理 · 电气工程与系统科学 2019-07-12 Kanwal K. Bhatia , Mark S. Graham , Louise Terry , Ashley Wood , Paris Tranos , Sameer Trikha , Nicolas Jaccard

To study whether it is possible to differentiate intermediate age-related macular degeneration (AMD) from healthy controls using partial optical coherence tomography (OCT) data, that is, restricting the input B-scans to certain pre-defined…

图像与视频处理 · 电气工程与系统科学 2023-07-17 Danilo A. Jesus , Eric F. Thee , Tim Doekemeijer , Daniel Luttikhuizen , Caroline Klaver , Stefan Klein , Theo van Walsum , Hans Vingerling , Luisa Sanchez

Advances in optical coherence tomography (OCT) have enabled noninvasive imaging of substructures of the human retina with high spatial resolution. OCT examinations are now a standard procedure in clinics and an integral part of ophthalmic…

人机交互 · 计算机科学 2022-12-22 Martin Röhlig , Oliver Stachs , Heidrun Schumann

Optical Coherence Tomography Angiography (OCTA) and its derived en-face projections provide high-resolution visualization of the retinal and choroidal vasculature, which is critical for the rapid and accurate diagnosis of retinal diseases.…

计算机视觉与模式识别 · 计算机科学 2025-09-10 Pooya Khosravi , Kun Han , Anthony T. Wu , Arghavan Rezvani , Zexin Feng , Xiaohui Xie

This paper provides a systematic survey of retinal diseases that cause visual impairments or blindness, emphasizing the importance of early detection for effective treatment. It covers both clinical and automated approaches for detecting…

图像与视频处理 · 电气工程与系统科学 2023-11-27 Hina Raja , Taimur Hassan , Bilal Hassan , Muhammad Usman Akram , Hira Raja , Alaa A Abd-alrazaq , Siamak Yousefi , Naoufel Werghi

Optical coherence tomography (OCT) has revolutionized retinal disease diagnosis with its high-resolution and three-dimensional imaging nature, yet its full diagnostic automation in clinical practices remains constrained by multi-stage…

Optical coherence tomography (OCT) imaging is a well-known technology for visualizing retinal layers and helps ophthalmologists to detect possible diseases. Accurate and early diagnosis of common retinal diseases can prevent the patients…

图像与视频处理 · 电气工程与系统科学 2022-03-04 Mohammad Rahimzadeh , Mahmoud Reza Mohammadi

Early detection of melanoma, a potentially lethal type of skin cancer with high prevalence worldwide, improves patient prognosis. In retrospective studies, artificial intelligence (AI) has proven to be helpful for enhancing melanoma…

Objective: The advent of Electronic Medical Records (EMR) with large electronic imaging databases along with advances in deep neural networks with machine learning has provided a unique opportunity to achieve milestones in automated image…

机器学习 · 统计学 2016-12-16 Cecilia S. Lee , Doug M. Baughman , Aaron Y. Lee

Diabetic Macular Edema (DME) is a leading cause of vision loss among patients with Diabetic Retinopathy (DR). While deep learning has shown promising results for automatically detecting this condition from fundus images, its application…

计算机视觉与模式识别 · 计算机科学 2025-10-09 Franco Javier Arellano , José Ignacio Orlando

Accurate segmentation of macular edema, a hallmark pathological feature in vision-threatening conditions such as age-related macular degeneration and diabetic macular edema, is essential for clinical diagnosis and management. To overcome…

计算机视觉与模式识别 · 计算机科学 2025-12-29 Li Yang , Yuting Liu

Purpose: Microaneurysms (MAs) have distinct, oval-shaped, hyperreflective walls on structural OCT, and inconsistent flow signal in the lumen with OCT angiography (OCTA). Their relationship to regional macular edema in diabetic retinopathy…

定量方法 · 定量生物学 2023-10-11 Min Gao , Tristan T. Hormel , Yukun Guo , Kotaro Tsuboi , Christina J. Flaxel , David Huang , Thomas S. Hwang , Yali Jia

Artificial intelligence (AI) has become a fundamental tool for assisting clinicians in analyzing ophthalmic images, such as optical coherence tomography (OCT). However, developing AI models often requires extensive annotation, and existing…

Inability to express the confidence level and detect unseen classes has limited the clinical implementation of artificial intelligence in the real-world. We developed a foundation model with uncertainty estimation (FMUE) to detect 11…

图像与视频处理 · 电气工程与系统科学 2024-06-26 Yuanyuan Peng , Aidi Lin , Meng Wang , Tian Lin , Ke Zou , Yinglin Cheng , Tingkun Shi , Xulong Liao , Lixia Feng , Zhen Liang , Xinjian Chen , Huazhu Fu , Haoyu Chen

Optical Coherence Tomography (OCT) provides a unique ability to image the eye retina in 3D at micrometer resolution and gives ophthalmologist the ability to visualize retinal diseases such as Age-Related Macular Degeneration (AMD). While…

计算机视觉与模式识别 · 计算机科学 2016-10-13 Stefanos Apostolopoulos , Carlos Ciller , Sandro I. De Zanet , Sebastian Wolf , Raphael Sznitman

We propose a new deep learning approach for automatic detection and segmentation of fluid within retinal OCT images. The proposed framework utilizes both ResNet and Encoder-Decoder neural network architectures. When training the network, we…

计算机视觉与模式识别 · 计算机科学 2017-08-21 Dustin Morley , Hassan Foroosh , Saad Shaikh , Ulas Bagci

Ocular disease affects billions of individuals unevenly worldwide. It continues to increase in prevalence with trends of growing populations of diabetic people, increasing life expectancies, decreasing ophthalmologist availability, and…

计算机与社会 · 计算机科学 2025-07-29 Shiv Garg , Ginny Berkemeier