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The pursuit of targeted therapies capable of overcoming biological barriers, including the tenacious blood-brain barrier, has spurred the investigation into stimuli-responsive microagents. This approach could improve therapeutic efficacy,…

Ultrasound-driven microbubbles rectify oscillatory motion into strong steady streaming flow [1, 2]. In this fluid dynamics video, we show size-dependent trapping, focusing and sorting of microparticles, utilizing the interaction between…

流体动力学 · 物理学 2010-10-19 Cheng Wang , Shreyas Jalikop , Sascha Hilgenfeldt

Ultrasound offers promising applications in biology and chemistry, but quantifying local ultrasound conditions remains challenging due to the lack of non-invasive measurement tools. We introduce antibubbles as novel optical reporters of…

Powered by acoustics, existing therapeutic and diagnostic procedures will become less invasive and new methods will become available that have never been available before. Acoustically driven microrobot navigation based on microbubbles is a…

机器人学 · 计算机科学 2023-08-04 Matthijs Schrage , Mahmoud Medany , Daniel Ahmed

Ultrasound localization microscopy offers new radiation-free diagnostic tools for vascular imaging deep within the tissue. Sequential localization of echoes returned from inert microbubbles with low-concentration within the bloodstream…

医学物理 · 物理学 2018-04-11 Oren Solomon , Ruud J. G. van Sloun , Hessel Wijkstra , Massimo Mischi , Yonina C. Eldar

Microbubbles excited by acoustic fields inside water oscillate, and generate acoustic radiation forces and drag-induced acoustic streaming. These forces can be harnessed in various biomedical applications such as targeted drug delivery and…

流体动力学 · 物理学 2022-05-26 Amit Dolev , Murat Kaynak , Mahmut Selman Sakar

Ultrasound contrast agents have been recently utilized in therapeutical implementations for targeted delivery of pharmaceutical substances. Radial pulsations of a cluster of encapsulated microbubbles under the action of an ultrasound field…

流体动力学 · 物理学 2018-11-19 S. Behniaa , M. Yahyavi , R. Habibpourbisafar , F. Mottaghi

Acoustic microstreaming has several industrial, therapeutic, and biomedical applications - Acoustic cleaning, micromixing, microfluid transport, hemolysis, sonoporation. The acoustic microstreaming due to the oscillation of ultrasound…

流体动力学 · 物理学 2022-01-19 Nima Mobadersany

The concept of a single-beam acoustical tweezer device which can simultaneously trap microparticles at different points is proposed and demonstrated through computational simulations. The device employs an ultrasound beam produced by a…

流体动力学 · 物理学 2014-10-02 Glauber T. Silva , Andre L. Baggio

Focused ultrasound stimulated microbubbles have been shown to be capable of inducing blood flow shutdown and necrosis in a range of tissue types in an approach termed antivascular ultrasound or mechanical ablation. In oncology, this…

医学物理 · 物理学 2022-10-17 Xiaoxiao Zhao , Carly Pellow , David E. Goertz

In this work, we will describe an experimental setup for a standing--wave ultrasound trap for air microbubbles in oil. We develop a model for the finite acoustic beam using the angular spectrum technique, and reconstruct the pressure field…

经典物理 · 物理学 2022-04-19 Matheus Azevedo Silva Pessôa , Antonio Alvaro Ranha Neves

Ultrasound-driven oscillating micro-bubbles have been used as active actuators in microfluidic devices to perform manifold tasks such as mixing, sorting and manipulation of microparticles. A common configuration consists on side-bubbles,…

Microbubbles - used as contrast agents in ultrasound imaging - are important tools in biomedical research, having been used together with ultrasound to develop significant diagnostic and therapeutic techniques. It has been suggested that…

医学物理 · 物理学 2022-11-23 Prashant Pandey

Ultrasound-driven microbubbles are increasingly being investigated for both molecular imaging and therapeutic applications. To be effective, these bubbles must be brought into close proximity or direct contact with the target site.…

流体动力学 · 物理学 2026-02-10 Marco Cattaneo , Outi Supponen

Efficient manipulation of light with sound in subwavelength-sized volumes is important for applications in photonics, phononics and biophysics, but remains elusive. We theoretically demonstrate the control of light with MHz-range ultrasound…

光学 · 物理学 2017-03-22 Ivan S. Maksymov , Andrew D. Greentree

Super-resolution ultrasound can image microvascular structure and flow at sub-wave-diffraction resolution based on localising and tracking microbubbles. Currently, tracking microbubbles accurately under limited imaging frame rates and high…

图像与视频处理 · 电气工程与系统科学 2023-04-04 Biao Huang , Jipeng Yan , Megan Morris , Victoria Sinnett , Navita Somaiah , Meng-Xing Tang

Drug delivery to the brain is limited by the blood-brain barrier (BBB). We developed a capacitive micromachined ultrasonic transducer (CMUT)-based transcranial focused ultrasound system capable of both delivering therapy via BBB opening and…

Ultrasound contrast imaging is a specialized imaging technique that applies microbubble contrast agents to traditional medical sonography, providing real-time visualization of blood flow and vessels. Gas-filled microbubbles are injected…

偏微分方程分析 · 数学 2024-12-17 Vanja Nikolić , Teresa Rauscher

Acoustic droplet vaporization denotes the phase-change of micron- and sub-micron-sized droplets upon the application of high-amplitude ultrasound. The asymmetric collapse of the incepted vapor bubbles within the droplets can give rise to…

流体动力学 · 物理学 2026-05-11 Anunay Prasanna , Samuele Fiorini , Gazendra Shakya , Outi Supponen

Ultrasound localization microscopy (ULM) refers to a promising medical imaging modality that systematically leverages the advantages of contrast-enhanced ultrasound (CEUS) to surpass the diffraction barrier and delineate the microvascular…

图像与视频处理 · 电气工程与系统科学 2022-09-22 Md Ashikuzzaman , Brandon Helfield , Hassan Rivaz
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