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Reliable cell segmentation and classification from biomedical images is a crucial step for both scientific research and clinical practice. A major challenge for more robust segmentation and classification methods is the large variations in…

Purpose: Lung nodule segmentation, i.e., the algorithmic delineation of the lung nodule surface, is a fundamental component of computational nodule analysis pipelines. We propose a new method for segmentation that is a machine learning…

Many automatic skin lesion diagnosis systems use segmentation as a preprocessing step to diagnose skin conditions because skin lesion shape, border irregularity, and size can influence the likelihood of malignancy. This paper presents,…

Automated 3-D breast ultrasound (ABUS) is a newfound system for breast screening that has been proposed as a supplementary modality to mammography for breast cancer detection. While ABUS has better performance in dense breasts, reading ABUS…

Live cell culture is crucial in biomedical studies for analyzing cell properties and dynamics in vitro. This study focuses on segmenting unstained live cells imaged with bright-field microscopy. While many segmentation approaches exist for…

We propose a cell segmentation method for analyzing images of densely clustered cells. The method combines the strengths of marker-controlled watershed transformation and a convolutional neural network (CNN). We demonstrate the method…

Correlative microscopy aims at combining two or more modalities to gain more information than the one provided by one modality on the same biological structure. Registration is needed at different steps of correlative microscopies…

Extracting hepatic vessels from abdominal images is of high interest for clinicians since it allows to divide the liver into functionally-independent Couinaud segments. In this respect, an automated liver blood vessel extraction is widely…

Document clustering is an unsupervised approach in which a large collection of documents (corpus) is subdivided into smaller, meaningful, identifiable, and verifiable sub-groups (clusters). Meaningful representation of documents and…

Extracting single-cell information from microscopy data requires accurate instance-wise segmentations. Obtaining pixel-wise segmentations from microscopy imagery remains a challenging task, especially with the added complexity of…

Lung cancer is a severe menace to human health, due to which millions of people die because of late diagnoses of cancer; thus, it is vital to detect the disease as early as possible. The Computerized chest analysis Tomography of scan is…

Tubular structure segmentation in medical images, e.g., segmenting vessels in CT scans, serves as a vital step in the use of computers to aid in screening early stages of related diseases. But automatic tubular structure segmentation in CT…

The human gut microbiome is associated with a large number of disease etiologies. As such, it is a natural candidate for machine learning based biomarker development for multiple diseases and conditions. The microbiome is often analyzed…

This paper presents a novel unsupervised segmentation method for 3D medical images. Convolutional neural networks (CNNs) have brought significant advances in image segmentation. However, most of the recent methods rely on supervised…

Biofilms are bacterial aggregates encased in a self-produced polymeric matrix which attach to moist surfaces and are extremely resistant to chemicals and antibiotics. Recent experiments show that their structure is defined by the interplay…

Improving connectivity and completeness are the most challenging aspects of liver vessel segmentation, especially for small vessels. These challenges require both learning the continuous vessel geometry, and focusing on small vessel…

Mass abnormality segmentation is a vital step for the medical diagnostic process and is attracting more and more the interest of many research groups. Currently, most of the works achieved in this area have used the Gray Level Co-occurrence…

Type-B Aortic Dissection (TBAD) is one of the most serious cardiovascular events characterized by a growing yearly incidence,and the severity of disease prognosis. Currently, computed tomography angiography (CTA) has been widely adopted for…

Analysis of microscopy images can provide insight into many biological processes. One particularly challenging problem is cell nuclear segmentation in highly anisotropic and noisy 3D image data. Manually localizing and segmenting each and…

Accurate detection and segmentation of diffuse large B-cell lymphoma (DLBCL) from PET images has important implications for estimation of total metabolic tumor volume, radiomics analysis, surgical intervention and radiotherapy. Manual…