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We consider the problem of inference for parameters selected to report only after some algorithm, the canonical example being inference for model parameters after a model selection procedure. The conditional correction for selection…

统计方法学 · 统计学 2019-01-30 Jelena Markovic , Jonathan Taylor , Jeremy Taylor

Unsupervised domain adaptation aims to address the problem of classifying unlabeled samples from the target domain whilst labeled samples are only available from the source domain and the data distributions are different in these two…

机器学习 · 计算机科学 2019-11-20 Qian Wang , Toby P. Breckon

Protein sequence design, determined by amino acid sequences, are essential to protein engineering problems in drug discovery. Prior approaches have resorted to evolutionary strategies or Monte-Carlo methods for protein design, but often…

Concurrent to the rapid progress in the development of neural-network based models in areas like natural language processing and computer vision, the need for creating explanations for the predictions of these black-box models has risen…

计算与语言 · 计算机科学 2025-08-18 Marc Brinner , Sina Zarriess

Motivation: Gene selection has become a common task in most gene expression studies. The objective of such research is often to identify the smallest possible set of genes that can still achieve good predictive performance. The problem of…

统计方法学 · 统计学 2015-11-25 Stéphane Guerrier , Nabil Mili , Roberto Molinari , Samuel Orso , Marco Avella-Medina , Yanyuan Ma

In this paper, we introduce the first principled adaptive-sampling procedure for learning a convex function in the $L_\infty$ norm, a problem that arises often in the behavioral and social sciences. We present a function-specific measure of…

机器学习 · 计算机科学 2018-08-28 Max Simchowitz , Kevin Jamieson , Jordan W. Suchow , Thomas L. Griffiths

Proteins perform critical processes in all living systems: converting solar energy into chemical energy, replicating DNA, as the basis of highly performant materials, sensing and much more. While an incredible range of functionality has…

生物大分子 · 定量生物学 2021-09-29 Leonardo V. Castorina , Rokas Petrenas , Kartic Subr , Christopher W. Wood

Determining the most appropriate features for machine learning predictive models is challenging regarding performance and feature acquisition costs. In particular, global feature choice is limited given that some features will only benefit…

机器学习 · 计算机科学 2026-03-17 Gabriel Bernardino , Anders Jonsson , Patrick Clarysse , Nicolas Duchateau

Decision-making problems often feature uncertainty stemming from heterogeneous and context-dependent human preferences. To address this, we propose a sequential learning-and-optimization pipeline to learn preference distributions and…

机器学习 · 计算机科学 2026-03-19 Benjamin Hudson , Laurent Charlin , Emma Frejinger

Discovering statistically significant patterns from databases is an important challenging problem. The main obstacle of this problem is in the difficulty of taking into account the selection bias, i.e., the bias arising from the fact that…

机器学习 · 统计学 2016-03-10 Shinya Suzumura , Kazuya Nakagawa , Mahito Sugiyama , Koji Tsuda , Ichiro Takeuchi

Many applications of machine learning methods involve an iterative protocol in which data are collected, a model is trained, and then outputs of that model are used to choose what data to consider next. For example, one data-driven approach…

We study a new framework for property testing of probability distributions, by considering distribution testing algorithms that have access to a conditional sampling oracle.* This is an oracle that takes as input a subset $S \subseteq [N]$…

数据结构与算法 · 计算机科学 2015-01-19 Clement Canonne , Dana Ron , Rocco A. Servedio

Plant breeding programs use data obtained from multi-environment selection experiments to produce improved varieties with the ultimate aim of maintaining high levels of genetic gain. Selection accuracy can be improved with the use of…

统计方法学 · 统计学 2026-05-13 Brian R Cullis , Alison B Smith , David GD Hughes , David Butler

Concept-based explanation methods aim at making machine learning models more transparent by finding the most important semantic features of an input (e.g., colors, patterns, shapes) for a given prediction task. However, these methods…

机器学习 · 计算机科学 2025-10-02 Jacopo Teneggi , Zhenzhen Wang , Paul H. Yi , Tianmin Shu , Jeremias Sulam

We investigate a class of chance-constrained combinatorial optimization problems. Given a pre-specified risk level $\epsilon \in [0,1]$, the chance-constrained program aims to find the minimum cost selection of a vector of binary decisions…

最优化与控制 · 数学 2020-06-02 Hao-Hsiang Wu , Simge Kucukyavuz

In this paper, we introduce an adaptive kernel method for solving the optimal filtering problem. The computational framework that we adopt is the Bayesian filter, in which we recursively generate an optimal estimate for the state of a…

数值分析 · 数学 2022-03-11 Zezhong Zhang , Richard Archibald , Feng Bao

By removing irrelevant and redundant features, feature selection aims to find a good representation of the original features. With the prevalence of unlabeled data, unsupervised feature selection has been proven effective in alleviating the…

机器学习 · 计算机科学 2024-03-25 Ziyuan Lin , Deanna Needell

The adoption of the distributed paradigm has allowed applications to increase their scalability, robustness and fault tolerance, but it has also complicated their structure, leading to an exponential growth of the applications'…

分布式、并行与集群计算 · 计算机科学 2017-05-23 Ioannis Giannakopoulos , Dimitrios Tsoumakos , Nectarios Koziris

We consider the problem of sampling from solutions defined by a set of hard constraints on a combinatorial space. We propose a new sampling technique that, while enforcing a uniform exploration of the search space, leverages the reasoning…

人工智能 · 计算机科学 2012-10-19 Stefano Ermon , Carla P. Gomes , Bart Selman

This paper studies chance-constrained stochastic optimization problems with finite support. It presents an iterative method that solves reduced-size chance-constrained models obtained by partitioning the scenario set. Each reduced problem…

最优化与控制 · 数学 2024-11-26 Marius Roland , Alexandre Forel , Thibaut Vidal