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Many researches have been working on the protein folding problem from more than half century. Protein folding is indeed one of the major unsolved problems in science. In this work, we discuss a model for the simulation of protein…

最优化与控制 · 数学 2008-11-20 A. Mucherino , O. Seref , P. M. Pardalos

Sequential learning in physical networks is hindered by catastrophic forgetting, where training a new task erases solutions to earlier ones. We show that we can significantly enhance memory of previous tasks by introducing a hard threshold…

无序系统与神经网络 · 物理学 2025-12-04 Purba Chatterjee , Marcelo Guzman , Andrea J. Liu

We consider optimal distributed computation of a given function of distributed data. The input (data) nodes and the sink node that receives the function form a connected network that is described by an undirected weighted network graph. The…

分布式、并行与集群计算 · 计算机科学 2015-07-15 Pooja Vyavahare , Nutan Limaye , D. Manjunath

We revisit the concept of minimal rigidity as applied to soft repulsive, frictionless sphere packings in two-dimensions with the introduction of the jamming graph. Minimal rigidity is a purely combinatorial property encoded via Laman's…

软凝聚态物质 · 物理学 2015-06-16 Jorge H. Lopez , L. Cao , J. M. Schwarz

We introduce several generalizations of classical computer science problems obtained by replacing simpler objective functions with general submodular functions. The new problems include submodular load balancing, which generalizes load…

数据结构与算法 · 计算机科学 2010-06-02 Zoya Svitkina , Lisa Fleischer

By removing parameters from deep neural networks, unstructured pruning methods aim at cutting down memory footprint and computational cost, while maintaining prediction accuracy. In order to tackle this otherwise intractable problem, many…

机器学习 · 计算机科学 2020-06-23 César Laurent , Camille Ballas , Thomas George , Nicolas Ballas , Pascal Vincent

Classical optimization is a cornerstone of the success of variational quantum algorithms, which often require determining the derivatives of the cost function relative to variational parameters. The computation of the cost function and its…

量子物理 · 物理学 2025-07-15 Muhammad Umer , Eleftherios Mastorakis , Dimitris G. Angelakis

The fundamental matrix can be estimated from point matches. The current gold standard is to bootstrap the eight-point algorithm and two-view projective bundle adjustment. The eight-point algorithm first computes a simple linear least…

Although existing medical image segmentation methods provide impressive pixel-wise accuracy, they often neglect topological correctness, making their segmentations unusable for many downstream tasks. One option is to retrain such models…

图像与视频处理 · 电气工程与系统科学 2024-09-17 Liu Li , Hanchun Wang , Matthew Baugh , Qiang Ma , Weitong Zhang , Cheng Ouyang , Daniel Rueckert , Bernhard Kainz

Designing and implementing systems as an interconnection of smaller subsystems is a common practice for modularity and standardization of components and design algorithms. Although not typically cast in this framework, many of these…

系统与控制 · 计算机科学 2016-06-29 Sefa Demirtas , Alan V. Oppenheim

Approximate unlearning has gained popularity as an approach to efficiently update an LLM so that it behaves (roughly) as if it was not trained on a subset of data to begin with. However, existing methods are brittle in practice and can…

机器学习 · 计算机科学 2025-04-08 Kevin Kuo , Amrith Setlur , Kartik Srinivas , Aditi Raghunathan , Virginia Smith

We report experimental results on the dynamics of a granular packing submitted to high-intensity focused ultrasound. Acoustic radiation pressure is shown to remotely induce local rearrangements within a pile as well as global motion around…

软凝聚态物质 · 物理学 2016-08-30 Pierre Lidon , Nicolas Taberlet , Sebastien Manneville

Recent semi-dense image matching methods have achieved remarkable success, but two long-standing issues still impair their performance. At the coarse stage, the over-exclusion issue of their mutual nearest neighbor (MNN) matching layer…

计算机视觉与模式识别 · 计算机科学 2026-04-09 Ke Jin , Jiming Chen , Qi Ye

We show that learning can be improved by using loss functions that evolve cyclically during training to emphasize one class at a time. In underparameterized networks, such dynamical loss functions can lead to successful training for…

机器学习 · 计算机科学 2021-06-24 Miguel Ruiz-Garcia , Ge Zhang , Samuel S. Schoenholz , Andrea J. Liu

Machine unlearning is an emerging field that selectively removes specific data samples from a trained model. This capability is crucial for addressing privacy concerns, complying with data protection regulations, and correcting errors or…

机器学习 · 计算机科学 2025-01-29 Zitong Li , Qingqing Ye , Haibo Hu

A new general algorithm for optimization of potential functions for protein folding is introduced. It is based upon gradient optimization of the thermodynamic stability of native folds of a training set of proteins with known structure. The…

凝聚态物理 · 物理学 2009-11-10 Ole Winther , Anders Krogh

There is proposed a method for improving the convergence of Fourier series by function systems, orthogonal at the segment, the application of which allows for smooth functions to receive uniformly convergent series. There is also proposed…

数值分析 · 数学 2018-05-18 Volodymyr Denysiuk

Structural network embedding is a crucial step in enabling effective downstream tasks for complex systems that aims to project a network into a lower-dimensional space while preserving similarities among nodes. We introduce a simple and…

社会与信息网络 · 计算机科学 2024-12-23 Giuseppe Squillace , Mirco Tribastone , Max Tschaikowski , Andrea Vandin

Tensor decomposition is one of the fundamental technique for model compression of deep convolution neural networks owing to its ability to reveal the latent relations among complex structures. However, most existing methods compress the…

计算机视觉与模式识别 · 计算机科学 2021-12-08 Bo-Shiuan Chu , Che-Rung Lee

With the growth of model and data sizes, a broad effort has been made to design pruning techniques that reduce the resource demand of deep learning pipelines, while retaining model performance. In order to reduce both inference and training…

机器学习 · 计算机科学 2026-02-24 Dayana Savostianova , Emanuele Zangrando , Gianluca Ceruti , Francesco Tudisco