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Complementary Learning Systems theory holds that intelligent agents need two learning systems. Semantic memory is encoded in the neocortex with dense, overlapping representations and acquires structured knowledge. Episodic memory is encoded…

机器学习 · 计算机科学 2025-09-03 Lucie Fontaine , Frédéric Alexandre

Declarative memory, the memory that can be "declared" in words or languages, is made up of two dissociated parts: episodic memory and semantic memory. This dissociation has its neuroanatomical basis episodic memory is mostly associated with…

神经元与认知 · 定量生物学 2026-02-10 Qi Zhang

Working memory involves the temporary retention of information over short periods. It is a critical cognitive function that enables humans to perform various online processing tasks, such as dialing a phone number, recalling misplaced…

人机交互 · 计算机科学 2025-04-29 Indrajeet Ghosh , Kasthuri Jayarajah , Nicholas Waytowich , Nirmalya Roy

A key issue to Alzheimer's disease clinical trial failures is poor participant selection. Participants have heterogeneous cognitive trajectories and many do not decline during trials, which reduces a study's power to detect treatment…

定量方法 · 定量生物学 2022-05-05 Angela Tam , César Laurent , Serge Gauthier , Christian Dansereau

To understand multifactorial conditions such as Alzheimers disease (AD) we need brain signatures that predict the impact of multiple pathologies and their interactions. To help uncover the relationships between brain circuits and cognitive…

Embedding learning, a.k.a. representation learning, has been shown to be able to model large-scale semantic knowledge graphs. A key concept is a mapping of the knowledge graph to a tensor representation whose entries are predicted by models…

人工智能 · 计算机科学 2016-05-10 Volker Tresp , Cristóbal Esteban , Yinchong Yang , Stephan Baier , Denis Krompaß

Associative memories in the brain receive and store patterns of activity registered by the sensory neurons, and are able to retrieve them when necessary. Due to their importance in human intelligence, computational models of associative…

An associative memory is a framework of content-addressable memory that stores a collection of message vectors (or a dataset) over a neural network while enabling a neurally feasible mechanism to recover any message in the dataset from its…

机器学习 · 统计学 2016-11-30 Arya Mazumdar , Ankit Singh Rawat

When someone mentions the name of a known person we immediately recall her face and possibly many other traits. This is because we possess the so-called associative memory, that is the ability to correlate different memories to the same…

神经元与认知 · 定量生物学 2010-08-26 Yuriy V. Pershin , Massimiliano Di Ventra

Timely and accurate diagnosis of neurodegenerative disorders, such as Alzheimer's disease, is central to disease management. Existing deep learning models require large-scale annotated datasets and often function as "black boxes".…

计算机视觉与模式识别 · 计算机科学 2025-04-15 Duy-Cat Can , Quang-Huy Tang , Huong Ha , Binh T. Nguyen , Oliver Y. Chén

Current LLM benchmarks focus on evaluating models' memory of facts and semantic relations, primarily assessing semantic aspects of long-term memory. However, in humans, long-term memory also includes episodic memory, which links memories to…

This paper explores deterioration in Alzheimers Disease using Machine Learning. Subjects were split into two datasets based on baseline diagnosis (Cognitively Normal, Mild Cognitive Impairment), with outcome of deterioration at final visit…

机器学习 · 计算机科学 2023-06-21 Henry Musto , Daniel Stamate , Ida Pu , Daniel Stahl

Episodic control has been proposed as a third approach to reinforcement learning, besides model-free and model-based control, by analogy with the three types of human memory. i.e. episodic, procedural and semantic memory. But the…

人工智能 · 计算机科学 2018-08-13 Johanni Brea

Alzheimer's dementia (AD) is of increasing concern as populations achieve longer lifespans. Many of the recent failed AD clinical trials recruiting cognitively intact individuals had a low number of AD events and were thus underpowered.…

统计方法学 · 统计学 2025-03-21 Julia Gallini , Zach Baucom , Yorghos Tripodis

Measuring transient functional connectivity is an important challenge in Electroencephalogram (EEG) research. Here, the rich potential for insightful, discriminative information of brain activity offered by high temporal resolution is…

神经元与认知 · 定量生物学 2025-02-11 Om Roy , Yashar Moshfeghi , Agustin Ibanez , Francisco Lopera , Mario A Parra , Keith M Smith

We explore a new class of brain encoding model by adding memory-related information as input. Memory is an essential brain mechanism that works alongside visual stimuli. During a vision-memory cognitive task, we found the non-visual brain…

计算机视觉与模式识别 · 计算机科学 2023-08-03 Huzheng Yang , James Gee , Jianbo Shi

The primate heteromodal cortex presents an evident functional modularity at a mesoscopic level, with physiological and anatomical evidence pointing to it as likely substrate of long-term memory. In order to investigate some of its…

神经元与认知 · 定量生物学 2021-12-09 Carlo Fulvi Mari

Cerebral microbleeds, markers of brain damage from vascular and amyloid pathologies, are linked to cognitive decline in aging, but their role in Alzheimer's disease (AD) onset and progression remains unclear. This study aimed to explore…

神经元与认知 · 定量生物学 2024-10-18 Saima Rathore , Jatin Chaudhary , Boning Tong , Selen Bozkurt

Cognitive impairment detection through spontaneous speech is a promising avenue for early diagnosis of Alzheimer's disease (AD) and mild cognitive impairment (MCI), where timely intervention can significantly improve patient outcomes. The…

声音 · 计算机科学 2025-02-19 Yifan Gao , Long Guo , Hong Liu

Deficits in working memory, which includes both the ability to learn and to retain information short-term, are a hallmark of many cognitive disorders. Our study analyzes data from a neuroscience experiment on animal subjects, where…

应用统计 · 统计学 2025-12-23 Maria Laura Battagliola , Laura J. Benoit , Sarah Canetta , Shizhe Zhang , R. Todd Ogden
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