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Nucleus segmentation and classification are the prerequisites in the workflow of digital pathology processing. However, it is very challenging due to its high-level heterogeneity and wide variations. This work proposes a deep neural network…

图像与视频处理 · 电气工程与系统科学 2022-12-07 Sen Yang , Jinxi Xiang , Xiyue Wang

Automatic nuclei segmentation and classification play a vital role in digital pathology. However, previous works are mostly built on data with limited diversity and small sizes, making the results questionable or misleading in actual…

图像与视频处理 · 电气工程与系统科学 2023-05-31 Kai Yao , Kaizhu Huang , Jie Sun , Amir Hussain

Identification and quantification of nuclei in colorectal cancer haematoxylin \& eosin (H\&E) stained histology images is crucial to prognosis and patient management. In computational pathology these tasks are referred to as nuclear…

定量方法 · 定量生物学 2022-03-08 Muhammad Dawood , Raja Muhammad Saad Bashir , Srijay Deshpande , Manahil Raza , Adam Shephard

We address the problem of automated nuclear segmentation, classification, and quantification from Haematoxylin and Eosin stained histology images, which is of great relevance for several downstream computational pathology applications. In…

计算机视觉与模式识别 · 计算机科学 2022-04-19 Lihao Liu , Chenyang Hong , Angelica I. Aviles-Rivero , Carola-Bibiane Schönlieb

Nuclear segmentation, classification and quantification within Haematoxylin & Eosin stained histology images enables the extraction of interpretable cell-based features that can be used in downstream explainable models in computational…

图像与视频处理 · 电气工程与系统科学 2022-02-25 Satoshi Kondo , Satoshi Kasai

The distribution and appearance of nuclei are essential markers for the diagnosis and study of cancer. Despite the importance of nuclear morphology, there is a lack of large scale, accurate, publicly accessible nucleus segmentation data. To…

图像与视频处理 · 电气工程与系统科学 2020-12-02 Le Hou , Rajarsi Gupta , John S. Van Arnam , Yuwei Zhang , Kaustubh Sivalenka , Dimitris Samaras , Tahsin M. Kurc , Joel H. Saltz

In computational pathology, automatic nuclei instance segmentation plays an essential role in whole slide image analysis. While many computerized approaches have been proposed for this task, supervised deep learning (DL) methods have shown…

Nuclear segmentation is an important step for profiling aberrant regions of histology sections. However, segmentation is a complex problem as a result of variations in nuclear geometry (e.g., size, shape), nuclear type (e.g., epithelial,…

计算机视觉与模式识别 · 计算机科学 2018-02-16 Mina Khoshdeli , Bahram Parvin

Oral epithelial dysplasia (OED) is a pre-malignant histopathological diagnosis given to lesions of the oral cavity. Predicting OED grade or whether a case will transition to malignancy is critical for early detection and appropriate…

图像与视频处理 · 电气工程与系统科学 2021-09-02 Adam J. Shephard , Simon Graham , R. M. Saad Bashir , Mostafa Jahanifar , Hanya Mahmood , Syed Ali Khurram , Nasir M. Rajpoot

Accurate segmentation and classification of nuclei in histology images is critical but challenging due to nuclei heterogeneity, staining variations, and tissue complexity. Existing methods often struggle with limited dataset variability,…

图像与视频处理 · 电气工程与系统科学 2025-01-22 Wenhua Zhang , Sen Yang , Meiwei Luo , Chuan He , Yuchen Li , Jun Zhang , Xiyue Wang , Fang Wang

Segmentation of nuclei regions from histological images is an important task for automated computer-aided analysis of histological images, particularly in the presence of impermissible color variation in the color appearance of stained…

图像与视频处理 · 电气工程与系统科学 2025-06-10 Suman Mahapatra , Pradipta Maji

Nuclei segmentation and classification is the first and most crucial step that is utilized for many different microscopy medical analysis applications. However, it suffers from many issues such as the segmentation of small objects,…

图像与视频处理 · 电气工程与系统科学 2022-03-07 Hussam Azzuni , Muhammad Ridzuan , Min Xu , Mohammad Yaqub

This paper addresses the task of nuclei segmentation in high-resolution histopathological images. We propose an auto- matic end-to-end deep neural network algorithm for segmenta- tion of individual nuclei. A nucleus-boundary model is…

计算机视觉与模式识别 · 计算机科学 2020-03-18 Yuxin Cui , Guiying Zhang , Zhonghao Liu , Zheng Xiong , Jianjun Hu

Segmentation of histological images is one of the most crucial tasks for many biomedical analyses including quantification of certain tissue type. However, challenges are posed by high variability and complexity of structural features in…

计算机视觉与模式识别 · 计算机科学 2020-07-30 Xiaohang Fu , Tong Liu , Zhaohan Xiong , Bruce H. Smaill , Martin K. Stiles , Jichao Zhao

Nuclei instance segmentation in hematoxylin and eosin (H&E)-stained images plays an important role in automated histological image analysis, with various applications in downstream tasks. While several machine learning and deep learning…

计算机视觉与模式识别 · 计算机科学 2026-01-29 Nima Torbati , Anastasia Meshcheryakova , Ramona Woitek , Sepideh Hatamikia , Diana Mechtcheriakova , Amirreza Mahbod

Nuclear segmentation, classification and quantification within Haematoxylin & Eosin stained histology images enables the extraction of interpretable cell-based features that can be used in downstream explainable models in computational…

图像与视频处理 · 电气工程与系统科学 2022-03-02 Chunhui Lin , Liukun Zhang , Lijian Mao , Min Wu , Dong Hu

We present HoVer-UNet, an approach to distill the knowledge of the multi-branch HoVerNet framework for nuclei instance segmentation and classification in histopathology. We propose a compact, streamlined single UNet network with a Mix…

图像与视频处理 · 电气工程与系统科学 2023-12-05 Cristian Tommasino , Cristiano Russo , Antonio Maria Rinaldi , Francesco Ciompi

In this paper, we develop a complete pipeline for stain normalization, segmentation, and classification of nuclei in hematoxylin and eosin (H&E) stained breast cancer histopathology images. In the first step, we use a CNN-based stain…

计算机视觉与模式识别 · 计算机科学 2018-11-12 Edwin Yuan , Junkyo Suh

Simultaneous segmentation and classification of nuclei in digital histology play an essential role in computer-assisted cancer diagnosis; however, it remains challenging. The highest achieved binary and multi-class Panoptic Quality (PQ)…

计算机视觉与模式识别 · 计算机科学 2024-04-29 Ibtihaj Ahmad , Syed Muhammad Israr , Zain Ul Islam

Nuclei classification provides valuable information for histopathology image analysis. However, the large variations in the appearance of different nuclei types cause difficulties in identifying nuclei. Most neural network based methods are…

计算机视觉与模式识别 · 计算机科学 2023-02-23 Wei Lou , Xiang Wan , Guanbin Li , Xiaoying Lou , Chenghang Li , Feng Gao , Haofeng Li
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