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An electronic circuit device, inspired on the FitzHugh-Nagumo model of neuronal excitability, was constructed and shown to operate with characteristics compatible with those of biological sensory neurons. The nonlinear dynamical model of…

The Fitzhugh-Nagumo neuronal model is used to explore the influence of the electric field on thermosensitive neurons' dynamics. This study investigates how the electric field affects polarization modulation in cell media induced by changes…

混沌动力学 · 物理学 2025-02-13 Ediline L. F. Nguessap , Fernando F. Ferreira , Antonio C. Roque

We here study a network of synaptic relations mingling excitatory and inhibitory neuron nodes that displays oscillations quite similar to electroencephalogram (EEG) brain waves, and identify abrupt variations brought about by swift synaptic…

神经元与认知 · 定量生物学 2021-02-17 Jorge Pretel , Joaquin J. Torres , J. Marro

Targeted electrical stimulation of the brain perturbs neural networks and modulates their rhythmic activity both at the site of stimulation and at remote brain regions. Understanding, or even predicting, this neuromodulatory effect is…

神经元与认知 · 定量生物学 2021-06-29 Christoforos Papasavvas , Peter Neal Taylor , Yujiang Wang

Neurostimulation using weak electric fields has generated excitement in recent years due to its potential as a medical intervention. However, study of this stimulation modality has been hampered by inconsistent results and large variability…

神经元与认知 · 定量生物学 2020-01-29 Frances Hutchings , Christopher Thornton , Chencheng Zhang , Yujiang Wang , Marcus Kaiser

Neuronal excitability is the phenomena that describes action potential generation due to a stimulus input. Commonly, neuronal excitability is divided into two classes: Type I and Type II, both having different properties that affect…

神经元与认知 · 定量生物学 2020-11-03 Jantine A. C. Broek , Guillaume Drion

The dynamical responses of complex neuronal networks to external stimulus injected on a \emph{single} neuron are investigated. Stimulating the largest-degree neuron in the network, it is found that as the intensity of the stimulus…

混沌动力学 · 物理学 2016-04-13 Mengjiao Chen , Weijie Lin , Hengtong Wang , Wei Ren , Xingang Wang

The Hodgkin-Huxley (HH) model is the currently accepted formalism of neuronal excitability. However, the HH model does not capture a number of biophysical behaviors associated with action potentials or propagating nerve impulses. Physical…

神经元与认知 · 定量生物学 2015-06-17 Jerel Mueller , William J. Tyler

Recent radio frequency scanning tunneling spectroscopy (rf-STS) experiments have demonstrated nuclear and electron spin excitations up to $\pm12\hbar$ in a single molecular spin quantum dot (qudot). Despite the profound experimental…

Deep Brain Stimulation (DBS) is an established and powerful treatment method in various neurological disorders. It involves chronically delivering electrical pulses to a certain stimulation target in the brain in order to alleviate the…

系统与控制 · 电气工程与系统科学 2023-10-03 Anna Franziska Frigge , Alexander Medvedev , Elena Jiltsova , Dag Nyholm

Transcranial direct current stimulation (tDCS) is known to have a modulatory effect on neural tissue and that it is polarity specific. It is also shown that tDCS demonstrated the lasting effect in therapeutic applications. The main aim of…

神经元与认知 · 定量生物学 2018-12-05 Milena Cukic , Miodrag Stokic , Slavoljub Radenkovic , Milos Ljubisavljevic , Dragoljub Donald Pokrajac

Transcranial Electrical Stimulation (TCES) and Deep Brain Stimulation (DBS) are two different applications of electrical current to the brain used in different areas of medicine. Both have a similar frequency dependence of their efficiency,…

神经元与认知 · 定量生物学 2019-07-15 Markus Schütt , Jens Christian Claussen

Transcranial electric stimulation (TES) can modulate intrinsic neural activity in the brain by injecting weak currents through electrodes attached to the scalp. TES has been widely used as a neuroscience tool to investigate how behavioural…

A new stimulation paradigm is presented for the stimulation of nerve cells by extracellular electric currents. In the new paradigm stimulation is achieved with the current spike induced by a voltage step whenever the voltage step is applied…

其他定量生物学 · 定量生物学 2016-03-08 Erich W. Schmid

Background: Direct electrical stimulation of the brain through intracranial electrodes is currently used to probe the epileptic brain as part of pre-surgical evaluation, and it is also being considered for therapeutic treatments through…

神经元与认知 · 定量生物学 2020-11-18 Christoforos A Papasavvas , Gabrielle M Schroeder , Beate Diehl , Gerold Baier , Peter N Taylor , Yujiang Wang

When a simple excitable system is continuously stimulated by a Poissonian external source, the response function (mean activity versus stimulus rate) generally shows a linear saturating shape. This is experimentally verified in some classes…

神经元与认知 · 定量生物学 2007-05-23 Mauro Copelli , Paulo R. A. Campos

Electrical stimulation of neural systems is a key tool for understanding neural dynamics and ultimately for developing clinical treatments. Many applications of electrical stimulation affect large populations of neurons. However,…

神经元与认知 · 定量生物学 2020-11-18 Caglar Cakan , Klaus Obermayer

Objectives: Permissible limits have been established by international guidelines and standards for human protection to electromagnetic field exposure to prevent adverse health effects stemming from electrostimulation in the most sensitive…

医学物理 · 物理学 2025-02-12 Jose Gomez-Tames , Thomas Tarnaud , Wout Joseph , Emmeric Tanghe

Understanding the relationship between nerve anatomy and the functional outcomes of electrical stimulation is critical for optimizing neural interface design. In this study, we conducted acute experiments on four pigs in which epineural…

信号处理 · 电气工程与系统科学 2025-10-06 Jonathan Baum , Chamot-Nonin Manon , Oppelt Vera , David Guiraud , Christine Azevedo Coste , Thomas Guiho

Interaction of electromagnetic (EM) waves with human tissue has been a longstanding research topic for electrical and biomedical engineers. However, few numbers of publications discuss the impacts of external EM-waves on neural stimulation…

神经元与认知 · 定量生物学 2020-11-26 Emad Arasteh Emamzadeh-Hashemi , Ailar Mahdizadeh
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