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The treatment of age-related macular degeneration (AMD) requires continuous eye exams using optical coherence tomography (OCT). The need for treatment is determined by the presence or change of disease-specific OCT-based biomarkers.…

图像与视频处理 · 电气工程与系统科学 2026-03-12 Timo Kepp , Helge Sudkamp , Claus von der Burchard , Hendrik Schenke , Peter Koch , Gereon Hüttmann , Johann Roider , Mattias P. Heinrich , Heinz Handels

Event-cameras have emerged as a revolutionary technology with a high temporal resolution that far surpasses standard active pixel cameras. This technology draws biological inspiration from photoreceptors and the initial retinal synapse.…

计算机视觉与模式识别 · 计算机科学 2024-12-09 Victoria Clerico , Shay Snyder , Arya Lohia , Md Abdullah-Al Kaiser , Gregory Schwartz , Akhilesh Jaiswal , Maryam Parsa

This paper uses a simple optogenetic model to compare the timing distortion between a randomly-generated target spike sequence and an externally-stimulated neuron spike sequence. Optogenetics is an emerging field of neuroscience where…

神经元与认知 · 定量生物学 2020-04-24 Adam Noel , Dimitrios Makrakis , Andrew W. Eckford

Recently, we have proposed a redox molecular hypothesis about the natural biophysical substrate of visual perception and imagery (B\'okkon, 2009. BioSystems; B\'okkon and D'Angiulli, 2009. Bioscience Hypotheses). Namely, the retina…

神经元与认知 · 定量生物学 2010-12-17 I. Bokkon , V. Salari , J. Tuszynski , I. Antal

Optical coherence tomography (OCT) is widely used for diagnosing and monitoring retinal diseases, such as age-related macular degeneration (AMD). The segmentation of biomarkers such as layers and lesions is essential for patient diagnosis…

计算机视觉与模式识别 · 计算机科学 2025-09-26 Botond Fazekas , Guilherme Aresta , Philipp Seeböck , Julia Mai , Ursula Schmidt-Erfurth , Hrvoje Bogunović

In addition to the optical aberrations, the magnitude of the optical cells of detectors is one of the most important parameters, which restricts the resolution of detectors. Adaptive optic and the methods of reducing the aberrations are…

光学 · 物理学 2007-05-23 S. Khademi , A. Darudi , M. Shahsavari

Optokinetic nystagmus (OKN) is an involuntary eye movement responsible for stabilizing retinal images in the presence of relative motion between an observer and the environment. Fully understanding the development of optokinetic nystagmus…

神经元与认知 · 定量生物学 2016-10-12 Chong Zhang , Jochen Triesch , Bertram E. Shi

With the growing prevalence of AI, demand increases for hardware that mimics the brain's ability to extract structure from limited data. In the retina, ganglion cells detect features from sparse inputs via lateral inhibition, where neurons…

Focusing on the complicated pathological features, such as blurred boundaries, severe scale differences between symptoms, background noise interference, etc., in the task of retinal edema lesions joint segmentation from OCT images and…

图像与视频处理 · 电气工程与系统科学 2024-01-03 Meng Wang , Kai Yu , Chun-Mei Feng , Ke Zou , Yanyu Xu , Qingquan Meng , Rick Siow Mong Goh , Yong Liu , Huazhu Fu

The spatio-angular resolution of a light field (LF) display is a crucial factor for delivering adequate spatial image quality and eliciting an accommodation response. Previous studies have modelled retinal image formation with an LF display…

图像与视频处理 · 电气工程与系统科学 2022-10-12 Yuta Miyanishi , Erdem Sahin , Atanas Gotchev

Objective. Patients implanted with the PRIMA photovoltaic subretinal prosthesis in geographic atrophy report form vision with the average acuity matching the 100um pixel size. Although this remarkable outcome enables them to read and write,…

人机交互 · 计算机科学 2026-01-09 Anna Kochnev Goldstein , Jungyeon Park , Yueming Zhuo , Nathan Jensen , Daniel Palanker

A foveated image can be entirely reconstructed from a sparse set of samples distributed according to the retinal sensitivity of the human visual system, which rapidly decreases with increasing eccentricity. The use of Generative Adversarial…

图形学 · 计算机科学 2023-04-18 Luca Surace , Marek Wernikowski , Cara Tursun , Karol Myszkowski , Radosław Mantiuk , Piotr Didyk

Multimode optical fibres are hair-thin strands of glass that efficiently transport light. They promise next-generation medical endoscopes that provide unprecedented sub-cellular image resolution deep inside the body. However, confining…

机器学习 · 计算机科学 2024-06-13 Yijie Zheng , Robert J. Kilpatrick , David B. Phillips , George S. D. Gordon

30 million Optical Coherence Tomography (OCT) imaging tests are issued annually to diagnose various retinal diseases, but accurate diagnosis of OCT scans requires trained eye care professionals who are still prone to making errors. With…

图像与视频处理 · 电气工程与系统科学 2022-10-04 Evan Wen , Rebecca Sorenson , Max Ehrlich

Retrieval-Augmented Generation (RAG) is widely used to augment the input to Large Language Models (LLMs) with external information, such as recent or domain-specific knowledge. Nonetheless, current models still produce closed-domain…

计算与语言 · 计算机科学 2026-04-20 Fabian Ridder , Laurin Lessel , Malte Schilling

We present an optimized conductance-based retina microcircuit simulator which transforms light stimuli into a series of graded and spiking action potentials through photo transduction. We use discrete retinal neuron blocks based on a…

神经元与认知 · 定量生物学 2020-01-16 Jason K. Eshraghian , Seungbum Baek , Wesley Thio , Yulia Sandamirskaya , Herbert H. C. Iu , Wei D. Lu

Optical molecular tomographic imaging is to reconstruct the concentration distribution of photon-molecular probes in a small animal from measured photon fluence rates. The localization and quantification of molecular probes is related to…

生物物理 · 物理学 2017-07-18 Wenxiang Cong , Xavier Intes , Ge Wang

Photon regeneration experiments searching for signatures of oscillations of photons into hypothetical very weakly interacting ultra-light particles, such as axions, axion-like and hidden-sector particles, have improved their sensitivity…

高能物理 - 唯象学 · 物理学 2015-05-18 Andreas Ringwald

Highest resolution laser spectroscopy has generally been limited to single trapped ion systems due to rapid decoherence which plagues neutral atom ensembles. Here, precision spectroscopy of ultracold neutral atoms confined in a trapping…

According to the theory of efficient coding, sensory systems are adapted to represent natural scenes with high fidelity and at minimal metabolic cost. Testing this hypothesis for sensory structures performing non-linear computations on high…

神经元与认知 · 定量生物学 2018-04-13 Ulisse Ferrari , Christophe Gardella , Olivier Marre , Thierry Mora