相关论文: High speed imaging of solid needle and liquid micr…
The development of needle-free drug injection systems is of great importance to global healthcare. However, in spite of its great potential and research history over many decades, these systems are not commonly used. One of the main…
Illuminating a water solution with a focused continuous wave laser produces a strong local heating of the liquid that leads to the nucleation of bubbles, also known as thermocavitation. During the growth of the bubble, the surrounding…
Injecting with needles causes fear, pain and contamination risks. Billions of injections every year also cause environmental burden in terms of material consumption and waste. Controlled microfluidic-jet injection systems offer a…
This study compares the penetration characteristics of impact-induced jets with those of laser-induced jets, focusing on the underlying penetration mechanism rather than device performance for needle-free injection. Using an impact-induced…
Non-invasive therapeutic ultrasound methods, such as high-intensity focused ultrasound (HIFU), have limited access to tissue targets shadowed by bones or presence of gas. This study demonstrates that an ultrasonically actuated medical…
A needle-free injector using a highly focused microjet has the potential to minimize the invasiveness of drug delivery. In this study, the jet penetration depth in a soft material-which is a critical parameter for practical needle-free…
Needle-free injector technology (NFIT) has drawn attention due to their advantages. By using NFIT, it can be used several time unlike a conventional needle. Also, it makes patients free from pain. Since NFIT by jet injection is achieved by…
The stability of high-speed liquid jets is crucial for applications ranging from precision printing to needle-free drug delivery, yet it is fundamentally limited by capillary-driven breakup. A common strategy to stabilize jets is to use…
This paper describes a simple yet novel system for generating a highly viscous microjet. The jet is produced inside a wettable thin tube partially submerged in a liquid. The gas-liquid interface inside the tube, which is initially concave,…
In this methods paper, we explore the capabilities of high-speed ultrasound imaging (USI) to study fast varying and complex multi-phase structures in liquids and soft materials. Specifically, we assess the advantages and the limitations of…
Continuous-wave lasers generated bubbles in microfluidic channels are proposed for applications such as needle-free jet injection due to their small size and affordable price of these lasers. However, water is transparent in the visible and…
This study experimentally and numerically investigates the dynamics of a high-speed liquid jet generated from the interaction of two tandem cavitation bubbles, termed bubble 1 and bubble 2, depending on their generation sequence. In our…
Hydrogels behave as viscoelastic soft solids and display a porous microstructure filled with water with typical amounts of 90\%~w/w or more. As such, these materials are highly sensitive to water loss through evaporation, which impacts…
Modelling the sudden depressurisation of superheated liquids through nozzles is a challenge because the pressure drop causes rapid flash boiling of the liquid. The resulting jet usually demonstrates a wide range of structures, including…
Magnetic robotics obviate the physical connections between the actuators and end effectors resulting in ultra-minimally invasive surgeries. Even though such a wireless actuation method is highly advantageous in medical applications, the…
Text-guided non-rigid editing involves complex edits for input images, such as changing motion or compositions within their surroundings. Since it requires manipulating the input structure, existing methods often struggle with preserving…
Scalable technologies for the production of bio-compatible complex microfibers with controllable size and composition at competitively high throughput are urgently needed in order to meet the growing demand for such microstructures in…
The paper describes the production of thin, focused microjets with velocities up to 850 m/s by the rapid vaporization of a small mass of liquid in an open liquid-filled capillary. The vaporization is caused by the absorption of a low-energy…
High-speed optical imaging of dynamic neuronal activity is essential yet challenging in neuroscience. While calcium imaging has been firmly established as a workhorse technique for monitoring neuronal activity, its limited temporal…
Impulsively generated focused jets play a significant role in various applications, including inkjet printing, needle-free drug delivery, and microfluidic devices. As the demand for generating jets and droplets from medium to highly viscous…