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Early detection of preventable diseases is important for better disease management, improved inter-ventions, and more efficient health-care resource allocation. Various machine learning approacheshave been developed to utilize information…

机器学习 · 计算机科学 2018-08-16 Jingshu Liu , Zachariah Zhang , Narges Razavian

Generating clinical synthetic text represents an effective solution for common clinical NLP issues like sparsity and privacy. This paper aims to conduct a systematic review on generating synthetic medical free-text by formulating…

计算与语言 · 计算机科学 2025-07-25 Basel Alshaikhdeeb , Ahmed Abdelmonem Hemedan , Soumyabrata Ghosh , Irina Balaur , Venkata Satagopam

Difficult-to-treat depression (DTD) has been proposed as a broader and more clinically comprehensive perspective on a person's depressive disorder where despite treatment, they continue to experience significant burden. We sought to develop…

计算与语言 · 计算机科学 2024-02-13 Isabelle Lorge , Dan W. Joyce , Niall Taylor , Alejo Nevado-Holgado , Andrea Cipriani , Andrey Kormilitzin

Physician burnout in the United States has reached critical levels, driven in part by the administrative burden of Electronic Health Record (EHR) documentation and complex diagnostic codes. To relieve this strain and maintain strict patient…

信息检索 · 计算机科学 2026-03-25 Peter Hartnett , Chung-Chi Huang , Sarah Hartnett , David Hartnett

Training medical image analysis models requires large amounts of expertly annotated data which is time-consuming and expensive to obtain. Images are often accompanied by free-text radiology reports which are a rich source of information. In…

Large language models (LLMs) are increasingly used to extract structured information from free-text clinical records, but prior work often focuses on single tasks, limited models, and English-language reports. We evaluated 15 open-weight…

We introduce SoftTiger, a clinical large language model (CLaM) designed as a foundation model for healthcare workflows. The narrative and unstructured nature of clinical notes is a major obstacle for healthcare intelligentization. We…

计算与语言 · 计算机科学 2024-08-21 Ye Chen , Igor Couto , Wei Cai , Cong Fu , Bruno Dorneles

In this study, we aim to address the task of assertion detection when extracting medical concepts from clinical notes, a key process in clinical natural language processing (NLP). Assertion detection in clinical NLP usually involves…

计算与语言 · 计算机科学 2024-02-01 Yuelyu Ji , Zeshui Yu , Yanshan Wang

Accurate prediction of clinical outcomes using Electronic Health Records (EHRs) is critical for early intervention, efficient resource allocation, and improved patient care. EHRs contain multimodal data, including both structured data and…

In this study, we investigated the ability of the large language model (LLM) to enhance healthcare data interoperability. We leveraged the LLM to convert clinical texts into their corresponding FHIR resources. Our experiments, conducted on…

计算与语言 · 计算机科学 2023-10-23 Yikuan Li , Hanyin Wang , Halid Yerebakan , Yoshihisa Shinagawa , Yuan Luo

Background: Natural Language Processing (NLP) is widely used to extract clinical insights from Electronic Health Records (EHRs). However, the lack of annotated data, automated tools, and other challenges hinder the full utilisation of NLP…

计算与语言 · 计算机科学 2023-06-23 Elias Hossain , Rajib Rana , Niall Higgins , Jeffrey Soar , Prabal Datta Barua , Anthony R. Pisani , Ph. D , Kathryn Turner}

Function is increasingly recognized as an important indicator of whole-person health, although it receives little attention in clinical natural language processing research. We introduce the first public annotated dataset specifically on…

计算与语言 · 计算机科学 2023-11-28 Tuan-Dung Le , Zhuqi Miao , Samuel Alvarado , Brittany Smith , William Paiva , Thanh Thieu

Cross-lingual transfer (CLT) is of various applications. However, labeled cross-lingual corpus is expensive or even inaccessible, especially in the fields where labels are private, such as diagnostic results of symptoms in medicine and user…

计算与语言 · 计算机科学 2022-06-15 Yinpeng Guo , Liangyou Li , Xin Jiang , Qun Liu

Drug repurposing plays a critical role in accelerating treatment discovery, especially for complex and rare diseases. Biomedical knowledge graphs (KGs), which encode rich clinical associations, have been widely adopted to support this task.…

计算与语言 · 计算机科学 2025-10-15 Chengrui Xiang , Tengfei Ma , Xiangzheng Fu , Yiping Liu , Bosheng Song , Xiangxiang Zeng

Simultaneous administration of multiple drugs can have synergistic or antagonistic effects as one drug can affect activities of other drugs. Synergistic effects lead to improved therapeutic outcomes, whereas, antagonistic effects can be…

计算与语言 · 计算机科学 2017-08-15 Sunil Kumar Sahu , Ashish Anand

The recent adoption of Electronic Health Records (EHRs) by health care providers has introduced an important source of data that provides detailed and highly specific insights into patient phenotypes over large cohorts. These datasets, in…

Electronic Healthcare Records contain large volumes of unstructured data, including extensive free text. Yet this source of detailed information often remains under-used because of a lack of methodologies to extract interpretable content in…

计算与语言 · 计算机科学 2018-07-10 M. Tarik Altuncu , Erik Mayer , Sophia N. Yaliraki , Mauricio Barahona

There is enormous enthusiasm and concerns in using large language models (LLMs) in healthcare, yet current assumptions are all based on general-purpose LLMs such as ChatGPT. This study develops a clinical generative LLM, GatorTronGPT, using…

Identifying medication discontinuations in electronic health records (EHRs) is vital for patient safety but is often hindered by information being buried in unstructured notes. This study aims to evaluate the capabilities of advanced…

计算与语言 · 计算机科学 2025-11-10 Chong Shao , Douglas Snyder , Chiran Li , Bowen Gu , Kerry Ngan , Chun-Ting Yang , Jiageng Wu , Richard Wyss , Kueiyu Joshua Lin , Jie Yang

Patient experience and care quality are crucial for a hospital's sustainability and reputation. The analysis of patient feedback offers valuable insight into patient satisfaction and outcomes. However, the unstructured nature of these…

计算与语言 · 计算机科学 2025-02-21 Hajar Sakai , Sarah S. Lam , Mohammadsadegh Mikaeili , Joshua Bosire , Franziska Jovin