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While dense biomedical embeddings achieve strong performance, their black-box nature limits their utility in clinical decision-making. Recent question-based interpretable embeddings represent text as binary answers to natural-language…

计算与语言 · 计算机科学 2026-03-04 Yixuan Tang , Zhenghong Lin , Yandong Sun , Wynne Hsu , Mong Li Lee , Anthony K. H. Tung

Contextual word embedding models such as ELMo (Peters et al., 2018) and BERT (Devlin et al., 2018) have dramatically improved performance for many natural language processing (NLP) tasks in recent months. However, these models have been…

计算与语言 · 计算机科学 2019-06-24 Emily Alsentzer , John R. Murphy , Willie Boag , Wei-Hung Weng , Di Jin , Tristan Naumann , Matthew B. A. McDermott

Biomedical Named Entity Recognition (BioNER) is a crucial step for analyzing Biomedical texts, which aims at extracting biomedical named entities from a given text. Different supervised machine learning algorithms have been applied for…

计算与语言 · 计算机科学 2019-08-19 Hamada A. Nayel , H. L. Shashirekha , Hiroyuki Shindo , Yuji Matsumoto

The COVID-19 has brought about a significant challenge to the whole of humanity, but with a special burden upon the medical community. Clinicians must keep updated continuously about symptoms, diagnoses, and effectiveness of emergent…

计算与语言 · 计算机科学 2020-12-02 Andres Carvallo , Denis Parra , Gabriel Rada , Daniel Perez , Juan Ignacio Vasquez , Camilo Vergara

Interpreting the decisions of deep learning models has been actively studied since the explosion of deep neural networks. One of the most convincing interpretation approaches is salience-based visual interpretation, such as Grad-CAM, where…

计算机视觉与模式识别 · 计算机科学 2023-10-17 Yiming Lei , Zilong Li , Yangyang Li , Junping Zhang , Hongming Shan

Clinical trials require strict adherence to medication protocols, yet dosing errors remain a persistent challenge affecting patient safety and trial integrity. We present an automated system for detecting dosing errors in unstructured…

人工智能 · 计算机科学 2026-04-23 Mohammad AL-Smadi

We support scientific writers in determining whether a written sentence is scientific, to which section it belongs, and suggest paraphrasings to improve the sentence. Firstly, we propose a regression model trained on a corpus of scientific…

计算与语言 · 计算机科学 2023-06-22 Justin Mücke , Daria Waldow , Luise Metzger , Philipp Schauz , Marcel Hoffman , Nicolas Lell , Ansgar Scherp

We introduce the sequence classification problem CIViC Evidence to the field of medical NLP. CIViC Evidence denotes the multi-label classification problem of assigning labels of clinical evidence to abstracts of scientific papers which have…

计算与语言 · 计算机科学 2024-07-08 Markus Hisch , Xing David Wang

Particle picking is a time-consuming step in single-particle analysis and often requires significant interventions from users, which has become a bottleneck for future automated electron cryo-microscopy (cryo-EM). Here we report a deep…

定量方法 · 定量生物学 2016-05-09 Feng Wang , Huichao Gong , Gaochao liu , Meijing Li , Chuangye Yan , Tian Xia , Xueming Li , Jianyang Zeng

This research introduces a novel psychometric method for analyzing textual data using large language models. By leveraging contextual embeddings to create contextual scores, we transform textual data into response data suitable for…

计算与语言 · 计算机科学 2025-09-12 Jinsong Chen

Biomedical research results are being published at a high rate, and with existing search engines, the vast amount of published work is usually easily accessible. However, reproducing published results, either experimental data or…

分子网络 · 定量生物学 2017-06-19 Kai-Wen Liang , Qinsi Wang , Cheryl Telmer , Divyaa Ravichandran , Peter Spirtes , Natasa Miskov-Zivanov

Motivation: Biomedical named-entity normalization involves connecting biomedical entities with distinct database identifiers in order to facilitate data integration across various fields of biology. Existing systems for biomedical named…

计算与语言 · 计算机科学 2023-10-24 Zainab Awan , Tim Kahlke , Peter Ralph , Paul Kennedy

Clinical trials need to recruit a sufficient number of volunteer patients to demonstrate the statistical power of the treatment (e.g., a new drug) in curing a certain disease. Clinical trial recruitment has a significant impact on trial…

机器学习 · 计算机科学 2024-07-19 Ling Yue , Sixue Xing , Jintai Chen , Tianfan Fu

We present BEEP (Biomedical Evidence-Enhanced Predictions), a novel approach for clinical outcome prediction that retrieves patient-specific medical literature and incorporates it into predictive models. Based on each individual patient's…

计算与语言 · 计算机科学 2022-11-17 Aakanksha Naik , Sravanthi Parasa , Sergey Feldman , Lucy Lu Wang , Tom Hope

Tools to explore scientific literature are essential for scientists, especially in biomedicine, where about a million new papers are published every year. Many such tools provide users the ability to search for specific entities (e.g.…

计算与语言 · 计算机科学 2021-07-05 Sunil Mohan , Rico Angell , Nick Monath , Andrew McCallum

Recent advances in large language models have led to renewed interest in natural language processing in healthcare using the free text of clinical notes. One distinguishing characteristic of clinical notes is their long time span over…

计算与语言 · 计算机科学 2023-07-17 Hongyi Zheng , Yixin Zhu , Lavender Yao Jiang , Kyunghyun Cho , Eric Karl Oermann

Deep learning models have revolutionized the field of medical image analysis, due to their outstanding performances. However, they are sensitive to spurious correlations, often taking advantage of dataset bias to improve results for…

计算机视觉与模式识别 · 计算机科学 2024-05-06 Diogo J. Araújo , M. Rita Verdelho , Alceu Bissoto , Jacinto C. Nascimento , Carlos Santiago , Catarina Barata

Benchmarking drug efficacy is a critical step in clinical trial design and planning. The challenge is that much of the data on efficacy endpoints is stored in scientific papers in free text form, so extraction of such data is currently a…

Using language models (LMs) pre-trained in a self-supervised setting on large corpora and then fine-tuning for a downstream task has helped to deal with the problem of limited label data for supervised learning tasks such as Named Entity…

计算与语言 · 计算机科学 2023-08-21 Pavlova Vera , Mohammed Makhlouf

Objective: Natural language processing can help minimize human intervention in identifying patients meeting eligibility criteria for clinical trials, but there is still a long way to go to obtain a general and systematic approach that is…